Development Level

Tbio 10 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased red blood cell distr... 1 | 41
hyperactivity 1 | 148
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
vertebral fusion 1 | 23

Disease

Carcinoma 7 | 11,493
medulloblastoma, large-cell 7 | 6,241
Cancer 6 | 2,499
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
pancreatic cancer 6 | 2,398
adult high grade glioma 5 | 3,801
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
cystic fibrosis 4 | 1,696
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
malignant mesothelioma 4 | 3,232
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Colorectal Neoplasms 3 | 243
Multiple myeloma 3 | 1,332
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
progressive supranuclear palsy 3 | 676
Ankylosis 2 | 28
Down syndrome 2 | 499
Fibrodysplasia ossificans progressiva 2 | 17
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Pulmonary Fibrosis 2 | 106
Sclerosteosis 2 | 9
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
sarcoidosis 2 | 370
ANONYCHIA 1 | 20
AORTIC VALVE DISEASE 2 1 | 2
Abnormal vertebral bodies 1 | 16
Absent fingernails 1 | 7
Acquired cubitus valgus 1 | 18
Adenomatous Polyposis Coli 1 | 16
Aortic Valve Disease 1 1 | 2
Aortic calcification 1 | 2
Aortic valve disorder 1 | 2
Aplasia/Hypoplasia of the middle phalanges of the toes 1 | 5
Bicuspid aortic valve 1 | 16
Broad hallux 1 | 29
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Congenital anomaly of spine 1 | 16
Craniosynostoses 1 | 16
Cutaneous finger syndactyly 1 | 11
Enlargement of the costochondral junction 1 | 4
Eye and adnexa disease 1 | 18
Fractures, Bone 1 | 13
Hypoplastic finger 1 | 17
Hypoplastic sternum 1 | 5
Hypoplastic-absent toenails 1 | 11
Juvenile osteoporosis 1 | 4
Long nose 1 | 15
Multiple vertebral anomalies 1 | 16
Narrow face 1 | 54
Osteoporosis, Juvenile 1 | 4
Otosclerosis 1 | 15
Precancerous Conditions 1 | 80
Proximally placed thumbs 1 | 17
Short distal phalanges 1 | 50
Short finger 1 | 17
Short sternum 1 | 5
Short to absent middle phalanges 1 | 5
Simple syndactyly of toes, first web space 1 | 23
Single transverse palmar crease 1 | 29
Spinal canal stenosis 1 | 12
Syndactyly of fingers 1 | 48
Tarsal Coalition 1 | 12
Thick upper lip vermilion 1 | 4
Thin face 1 | 54
Thin hypoplastic alae nasi 1 | 51
Ureteral obstruction 1 | 33
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

negative regulation of pathway... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
Gremlin-1 GREM1 Tbio Non-IDG -2.91296 826.9 397
Sorting nexin-25 SNX25 Tbio Non-IDG -0.47192 3.47 114
Protein TMEPAI PMEPA1 Tbio Non-IDG -1.35527 24.8 90
Serine-threonine kinase receptor-associated protein STRAP Tbio Enzyme -1.35902 23.9 139
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Low-density lipoprotein receptor class A domain-containing protein 4 LDLRAD4 Tbio Non-IDG -1.56623 26.5 53
Mothers against decapentaplegic homolog 7 SMAD7 Tbio Transcription Factor -2.81953 638.7 387