Development Level

Tbio 11 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal iris morphology 1 | 13
abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased startle reflex 1 | 75
increased circulating glucose ... 1 | 24
trunk curl 1 | 16

Disease

psoriasis 14 | 6,694
Carcinoma 12 | 11,493
lung cancer 11 | 4,740
glioblastoma 9 | 5,792
Cancer 8 | 2,499
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
colon cancer 7 | 1,478
ependymoma 7 | 4,679
non-small cell lung cancer 7 | 2,890
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
Osteoporosis 6 | 363
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Bipolar Disorder 5 | 666
Down syndrome 5 | 499
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
lung carcinoma 5 | 2,843
Arthritis 4 | 290
Astrocytoma, Pilocytic 4 | 3,081
Breast Neoplasms 4 | 445
Congenital deafness 4 | 185
Deafness 4 | 198
Depressive disorder 4 | 409
Hearing Loss, Partial 4 | 185
Hypertension 4 | 396
Mammary Neoplasms 4 | 425
Orbital separation excessive 4 | 244
Schizophrenia 4 | 1,160
Syndactyly 4 | 88
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,855
hearing impairment 4 | 199
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
ulcerative colitis 4 | 1,819
Adenoma 3 | 167
Alzheimer's disease 3 | 658
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Big calvaria 3 | 147
Brachydactyly 3 | 156
Calcinosis 3 | 70
Cell Transformation, Neoplastic 3 | 97
Class III malocclusion 3 | 78
Colorectal Neoplasms 3 | 243
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Exophthalmos 3 | 112
Failure to gain weight 3 | 365
Hydrocephalus 3 | 152
Hypertensive disease 3 | 292
Hypertrophy of lower jaw 3 | 78
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of mandible 3 | 78
Increased size of skull 3 | 147
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Lymphoid leukemia 3 | 160
Mandibular hyperplasia 3 | 78
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Neoplastic Cell Transformation 3 | 89
Osteoarthritis 3 | 184
Osteosclerosis 3 | 31
Pediatric failure to thrive 3 | 365
Prominent eyes 3 | 96
Prominent globes 3 | 96
Prostatic Neoplasms 3 | 495
Protruding eyes 3 | 96
Pulmonary hypertension 3 | 85
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
mandibular excess (physical finding) 3 | 78
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Abnormality of pulmonary valve 2 | 23
Frequent fractures 2 | 53
High forehead 2 | 102
Increased fracture rate 2 | 53
Inflammation 2 | 120
Nail dysplasia 2 | 52
Tall forehead 2 | 102
Varying degree of multiple fractures 2 | 53

Tissue

Endocrine System 17 | 18,159
Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Respiratory system 15 | 16,393
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 11 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145

GO Process

negative regulation of ossific... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurogenic locus notch homolog protein 1 NOTCH1 Tchem Non-IDG -4.08071 11843.2 916
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Calcitonin CALCA Tbio Non-IDG -3.70355 8831.3 1309
Transcription factor SOX-9 SOX9 Tbio Transcription Factor -3.14522 1332.4 657
Sclerostin SOST Tbio Non-IDG -2.95679 946.9 393
Tryptophan 5-hydroxylase 1 TPH1 Tclin Enzyme -2.93036 772.3 415
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Recombining binding protein suppressor of hairless RBPJ Tbio Transcription Factor -2.67790 444.5 266
Secreted frizzled-related protein 1 SFRP1 Tchem Non-IDG -2.40092 279.5 264
Myocyte-specific enhancer factor 2C MEF2C Tbio Transcription Factor -2.30705 184.5 974