Development Level

Tbio 39 | 11,445
Tchem 13 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
convulsive seizures 2 | 13
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood uric acid leve... 1 | 5
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased granulocyte number 1 | 1
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 38 | 11,493
medulloblastoma, large-cell 32 | 6,241
ovarian cancer 31 | 8,520
glioblastoma 29 | 5,792
lung cancer 25 | 4,740
ependymoma 24 | 4,679
osteosarcoma 24 | 7,950
atypical teratoid / rhabdoid tumor 23 | 5,112
oligodendroglioma 23 | 2,850
Astrocytoma, Pilocytic 22 | 3,081
adult high grade glioma 21 | 3,801
group 3 medulloblastoma 21 | 4,104
lung carcinoma 21 | 2,843
malignant mesothelioma 21 | 3,232
subependymal giant cell astrocytoma 21 | 2,287
psoriasis 19 | 6,694
Cancer 18 | 2,499
astrocytic glioma 17 | 2,597
Schizophrenia 16 | 1,160
Breast cancer 14 | 3,578
invasive ductal carcinoma 14 | 2,951
pituitary cancer 14 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Kidney cancer 11 | 2,613
Pick disease 11 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
primitive neuroectodermal tumor 11 | 3,035
Down syndrome 10 | 499
pancreatic cancer 10 | 2,398
astrocytoma 9 | 1,146
group 4 medulloblastoma 9 | 1,855
ulcerative colitis 9 | 1,819
Parkinson's disease 8 | 392
colon cancer 8 | 1,478
lung adenocarcinoma 8 | 2,716
non-small cell lung cancer 8 | 2,890
Intellectual disability 7 | 1,016
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
cystic fibrosis 7 | 1,696
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis 7 | 2,010
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
Epilepsy 6 | 792
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Muscle hypotonia 6 | 571
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
active Crohn's disease 6 | 922
diabetes mellitus 6 | 1,728
gastric carcinoma 6 | 807
interstitial cystitis 6 | 2,312
Alzheimer's disease 5 | 658
Amyotrophic lateral sclerosis 5 | 451
Liver Cirrhosis 5 | 181
Liver Cirrhosis, Experimental 5 | 769
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
adrenocortical carcinoma 5 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
Alcoholic Intoxication, Chronic 4 | 289
Attention deficit hyperactivity disorder 4 | 278
Breast Neoplasms 4 | 445
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Liver cancer 4 | 604
Low intelligence 4 | 645
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Parkinson Disease 4 | 64
Poor school performance 4 | 645
non-small cell lung carcinoma 4 | 317
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Hepatomegaly 3 | 285
Hypertension 3 | 396
Kidney disease 3 | 430
Reperfusion Injury 3 | 86
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
nasopharyngeal carcinoma 3 | 1,058

Tissue

Digestive Tract 54 | 17,369
Female tissues 54 | 17,400
Skin and soft tissues 54 | 17,230
Endocrine System 53 | 18,159
Male tissues 53 | 17,142
Blood and immune system 52 | 16,909
Nervous System 52 | 16,725
Respiratory system 52 | 16,393
Urinary Tract 52 | 16,678
Liver and Pancreas 51 | 16,750
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 14 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GO Process

negative regulation of neuron ... 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX6 TBX6 Tbio Transcription Factor -1.78720 63.0 315
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Reticulon-4 receptor-like 2 RTN4RL2 Tbio Non-IDG -1.11916 14.5 90
Reticulon-4 receptor-like 1 RTN4RL1 Tbio Non-IDG -0.81334 6.43 92
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Protein ZNF365 ZNF365 Tbio Non-IDG -1.44015 50.6 273
B-cell lymphoma/leukemia 11A BCL11A Tbio Transcription Factor -2.16270 151.0 300