Development Level

Tbio 24 | 10,625
Tchem 10 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Phenotype

abnormal tooth morphology 2 | 24
decreased circulating glucose ... 2 | 121
decreased rib number 2 | 59
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
absent vibrissae 1 | 14
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 19
decreased memory-marker CD4-po... 1 | 4
decreased thoracic vertebrae n... 1 | 7
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
preweaning lethality, complete... 1 | 633
tremors 1 | 34
vertebral fusion 1 | 23

Disease

Cancer 21 | 2,346
glioblastoma 19 | 5,572
ovarian cancer 19 | 8,491
psoriasis 19 | 6,685
diabetes mellitus 15 | 1,663
medulloblastoma, large-cell 15 | 6,234
osteosarcoma 15 | 7,933
atypical teratoid / rhabdoid tumor 14 | 4,369
Alzheimer's disease 13 | 644
Parkinson's disease 13 | 364
lung cancer 13 | 4,473
Neurodegenerative disease 12 | 383
Dementia 10 | 129
Obesity 10 | 616
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
invasive ductal carcinoma 10 | 2,950
ulcerative colitis 10 | 2,087
Heart disease 9 | 279
Liver disease 9 | 219
malignant mesothelioma 9 | 3,163
Breast cancer 8 | 3,098
Toxic encephalopathy 8 | 131
ependymoma 8 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
medulloblastoma 8 | 1,524
Brain disease 7 | 84
Hyperglycemia 7 | 120
Inflammation 7 | 109
Kidney disease 7 | 397
Metabolic syndrome X 7 | 155
Myocardial Infarction 7 | 126
Nerve Degeneration 7 | 73
Parkinson Disease 7 | 105
Pick disease 7 | 1,893
Prostatic Neoplasms 7 | 471
astrocytic glioma 7 | 2,241
lung adenocarcinoma 7 | 2,714
lung carcinoma 7 | 2,844
oligodendroglioma 7 | 2,849
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
Atherosclerosis 6 | 275
Cerebrovascular disease 6 | 231
Fatty liver disease 6 | 86
Hypertension 6 | 293
Lung Neoplasms 6 | 171
Mammary Neoplasms 6 | 410
Pneumonia 6 | 133
adrenocortical carcinoma 6 | 1,427
primitive neuroectodermal tumor 6 | 3,031
tuberculosis 6 | 1,563
Anemia 5 | 252
Arthritis 5 | 248
Coronary artery disease 5 | 240
Crohn's disease 5 | 304
Diabetes Mellitus, Experimental 5 | 106
Drug-Induced Liver Injury 5 | 118
Huntington's disease 5 | 72
Inflammatory bowel disease 5 | 142
Thrombocytopenia 5 | 105
Vascular disease 5 | 281
adult high grade glioma 5 | 2,148
gastric carcinoma 5 | 832
group 4 medulloblastoma 5 | 1,875
interstitial cystitis 5 | 2,299
non-small cell lung cancer 5 | 2,798
non-small cell lung carcinoma 5 | 413
ovarian neoplasm 5 | 97
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pediatric high grade glioma 5 | 2,712
pituitary cancer 5 | 1,972
posterior fossa group B ependymoma 5 | 1,530
primary pancreatic ductal adenocarcinoma 5 | 1,271
Amyotrophic Lateral Sclerosis 4 | 432
Asthma 4 | 349
Atopic dermatitis 4 | 944
Autistic Disorder 4 | 320
Carcinoma 4 | 2,147
Cardiomyopathies 4 | 90
Crohn Disease 4 | 97
Diabetes Mellitus, Non-Insulin-Dependent 4 | 161
Fibrosis 4 | 40
Hypersensitivity reaction type II disease 4 | 235
Hypertensive disease 4 | 193
Lipid metabolism disorder 4 | 102
Liver neoplasms 4 | 108
Multiple myeloma 4 | 1,327
Myopathy 4 | 128
Neoplasm Invasiveness 4 | 127
Neoplasm Metastasis 4 | 138
Osteoporosis 4 | 259
PARKINSON DISEASE, LATE-ONSET 4 | 20
Peripheral Neuropathy 4 | 303
Rheumatoid Arthritis 4 | 1,170
Schizophrenia 4 | 503
astrocytoma 4 | 1,493
colon cancer 4 | 1,475
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 2,254

Tissue

Blood and immune system 38 | 17,994
Digestive Tract 38 | 18,472
Endocrine System 38 | 18,511
Female tissues 38 | 18,646
Liver and Pancreas 38 | 18,135
Nervous System 38 | 18,560
Cardiovascular System 37 | 17,957
Male tissues 37 | 17,968
Respiratory system 37 | 17,483
Skin and soft tissues 37 | 18,114
Urinary Tract 37 | 18,443

Target Family

Non-IDG 19 | 11,969
Enzyme 8 | 4,146
Kinase 4 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

negative regulation of neuron ... 38 | 38
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.56782 368.4 441
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.04076 1184.8 589
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.11491 14.8 25
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.26734 207.5 1100
Probable cation-transporting ATPase 13A2 ATP13A2 Tbio Transporter -2.00056 92.5 127
Fructose-2,6-bisphosphatase TIGAR TIGAR Tbio Enzyme -1.66337 51.1 244
Interleukin-6 IL6 Tclin Non-IDG -4.47638 28484.7 1664
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.43962 2958.6 656
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Tchem Kinase -3.03328 1111.2 722