Development Level

Tbio 79 | 11,445
Tchem 33 | 1,598
Tclin 15 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 6 | 499
abnormal bone structure 4 | 187
abnormal embryo size 3 | 220
edema 3 | 59
hypoactivity 3 | 132
abnormal sleep behavior 2 | 70
decreased circulating glucose ... 2 | 126
decreased circulating phosphat... 2 | 27
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased startle reflex 2 | 75
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
pallor 1 | 34
respiratory system phenotype 1 | 2
short tibia 1 | 97

Disease

Carcinoma 88 | 11,493
ovarian cancer 74 | 8,520
glioblastoma 73 | 5,792
medulloblastoma, large-cell 67 | 6,241
psoriasis 59 | 6,694
Cancer 58 | 2,499
osteosarcoma 58 | 7,950
atypical teratoid / rhabdoid tumor 56 | 5,112
ependymoma 56 | 4,679
adult high grade glioma 52 | 3,801
lung cancer 52 | 4,740
Schizophrenia 44 | 1,160
group 3 medulloblastoma 44 | 4,104
malignant mesothelioma 44 | 3,232
oligodendroglioma 42 | 2,850
Astrocytoma, Pilocytic 40 | 3,081
Breast cancer 40 | 3,578
astrocytic glioma 35 | 2,597
lung adenocarcinoma 33 | 2,716
primitive neuroectodermal tumor 33 | 3,035
Autosomal recessive predisposition 31 | 1,442
invasive ductal carcinoma 31 | 2,951
Kidney cancer 28 | 2,613
non-small cell lung cancer 28 | 2,890
Intellectual disability 27 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
ulcerative colitis 27 | 1,819
Bipolar Disorder 26 | 666
Parkinson's disease 26 | 392
Alzheimer's disease 25 | 658
interstitial cystitis 25 | 2,312
subependymal giant cell astrocytoma 25 | 2,287
Epilepsy 24 | 792
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
Depressive disorder 23 | 409
Neurodegenerative disease 23 | 414
Pick disease 22 | 1,894
diabetes mellitus 22 | 1,728
pancreatic cancer 22 | 2,398
pituitary cancer 22 | 1,972
tuberculosis 21 | 2,010
astrocytoma 20 | 1,146
ductal carcinoma in situ 20 | 1,745
group 4 medulloblastoma 20 | 1,855
lung carcinoma 20 | 2,843
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Poor school performance 19 | 645
Seizures 19 | 596
colon cancer 19 | 1,478
Breast Neoplasms 18 | 445
Obesity 18 | 678
Toxic encephalopathy 18 | 141
cystic fibrosis 18 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
nasopharyngeal carcinoma 18 | 1,058
Autistic Disorder 17 | 364
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Mammary Neoplasms 17 | 425
Mental and motor retardation 17 | 608
breast carcinoma 17 | 1,638
Multiple myeloma 16 | 1,332
Muscle hypotonia 16 | 571
adrenocortical carcinoma 16 | 1,428
Nerve Degeneration 15 | 121
Status Epilepticus 15 | 98
Anxiety 14 | 136
cutaneous lupus erythematosus 14 | 1,057
Down syndrome 13 | 499
Lung Neoplasms 13 | 232
Mental Depression 13 | 333
Parkinsonian Disorders 13 | 56
Rheumatoid arthritis 13 | 1,191
Short stature 13 | 531
Alcoholic Intoxication, Chronic 12 | 289
Amyotrophic lateral sclerosis 12 | 451
Carcinoma, Hepatocellular 12 | 228
Dementia 12 | 175
Liver carcinoma 12 | 240
Major Depressive Disorder 12 | 301
Myocardial Infarction 12 | 151
Parkinson Disease 12 | 64
Stomach Neoplasms 12 | 300
gastric cancer 12 | 459
hearing impairment 12 | 199
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Asthma 11 | 385
Blepharoptosis 11 | 231
Cerebral atrophy 11 | 178
Liver Cirrhosis, Experimental 11 | 769
Low set ears 11 | 181
Neuropathy 11 | 261
Orbital separation excessive 11 | 244
Prostatic Neoplasms 11 | 495
Unipolar Depression 11 | 250
Waldenstrons macroglobulinemia 11 | 765
non primary Sjogren syndrome sicca 11 | 891

Tissue

Endocrine System 129 | 18,159
Digestive Tract 127 | 17,369
Nervous System 127 | 16,725
Female tissues 126 | 17,400
Skin and soft tissues 126 | 17,230
Blood and immune system 125 | 16,909
Male tissues 123 | 17,142
Liver and Pancreas 121 | 16,750
Urinary Tract 120 | 16,678
Respiratory system 117 | 16,393
Cardiovascular System 107 | 15,192

Target Family

Non-IDG 60 | 12,091
Enzyme 22 | 4,145
Kinase 18 | 634
Transcription Factor 18 | 1,400
Ion Channel 5 | 344
GPCR 4 | 408
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

negative regulation of neuron ... 131 | 131
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein B1 FOXB1 Tbio Transcription Factor -1.17019 15.7 110
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Protein BTG2 BTG2 Tbio Non-IDG -2.10376 142.7 209
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Alanine--tRNA ligase, cytoplasmic AARS Tbio Enzyme -2.49617 295.2 140
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735