Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
increased heart weight 1 | 62
polycystic kidney 1 | 15

Disease

Parkinson's disease 3 | 392
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Amyotrophic lateral sclerosis 2 | 451
Anxiety 2 | 136
Anxiety disease 2 | 113
Brain disease 2 | 96
Carcinoma 2 | 11,493
Depressive disorder 2 | 409
Nerve Degeneration 2 | 121
Neurodegenerative Disorders 2 | 79
Neurodegenerative disease 2 | 414
Parkinson Disease 2 | 64
Parkinsonian Disorders 2 | 56
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
colon cancer 2 | 1,478
interstitial lung disease 2 | 298
psoriasis 2 | 6,694
Abnormal brain FDG positron emission tomography 1 | 9
Alexia 1 | 6
Apathy 1 | 16
Aphasia 1 | 26
Apraxia 1 | 26
Apraxias 1 | 27
Behavioral variant of frontotemporal dementia 1 | 8
Blurred vision 1 | 19
Ceroid lipofuscinosis, neuronal 1, infantile 1 | 10
Compulsive hoarding 1 | 7
Deglutition Disorders 1 | 132
Developmental arithmetic disorder 1 | 8
Difficulty making arithmetical calculations 1 | 8
Diplopia 1 | 8
Duodenal Ulcer due to H. Pylori 1 | 7
Duodenal ulcer disease 1 | 7
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysphasia 1 | 23
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Erosive esophagitis 1 | 6
Excess nuchal skin 1 | 30
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Fatty liver disease 1 | 103
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Gait imbalance 1 | 17
Gastric Hypersecretory Conditions 1 | 5
Gastric ulcer 1 | 33
Grammar-specific speech disorder 1 | 6
Hyperglycemia 1 | 137
Hyperorality 1 | 7
Hyperphagia 1 | 23
Increased appetite (finding) 1 | 23
Irritation - emotion 1 | 68
Koolen de Vries syndrome 1 | 18
Kyphoscoliosis deformity of spine 1 | 60
Learning Disorders 1 | 29
Maintenance of Healing Duodenal Ulcer 1 | 7
Memory Disorders 1 | 40
Memory Loss 1 | 40
Memory impairment 1 | 40
Morphological abnormality of the pyramidal tract 1 | 12
Multiple system atrophy 1 | 29
Muscle Cramp 1 | 55
Muscle Rigidity 1 | 49
Mutism 1 | 17
Neurodegenerative Diseases 1 | 38
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Ophthalmoparesis 1 | 11
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
PARKINSON DISEASE, LATE-ONSET 1 | 20
Pain 1 | 103
Paralysed 1 | 42
Parkinson Disease 6, Autosomal Recessive Early-Onset 1 | 3
Pelvic inflammatory disease 1 | 21
Peptic Ulcer 1 | 27
Pick's disease 1 | 15
Poor speech 1 | 37
Primary Progressive Nonfluent Aphasia 1 | 7
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Problems speaking 1 | 37
Pyramidal sign 1 | 29
Pyramidal tract disease 1 | 12
Repeated speech 1 | 9
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Semantic Dementia 1 | 7
Social disinhibition 1 | 14
Spoken Word Recognition Deficit 1 | 6
Supranuclear gaze palsy 1 | 6
Temporal cortical atrophy 1 | 6
Xerostomia 1 | 42
Young onset Parkinson disease 1 | 10
Zollinger-Ellison syndrome 1 | 18

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Kinase 1 | 634

GO Process

negative regulation of mitocho... 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Microtubule-associated protein tau MAPT Tchem Non-IDG -3.88207 7239.3 3951
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PPARGC1A Tbio Non-IDG -2.86449 728.1 274