Development Level

Tbio 7 | 11,445

IMPC Phenotype

female infertility 2 | 60
male infertility 2 | 123
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
increased basophil cell number 1 | 7
increased bone mineral content 1 | 108
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
thrombocytopenia 1 | 56

Disease

Carcinoma 3 | 11,493
atypical teratoid / rhabdoid tumor 3 | 5,112
ovarian cancer 3 | 8,520
Arthritis 2 | 290
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cryptorchidism 2 | 296
Depressive disorder 2 | 409
Hypogonadism 2 | 173
Infertility 2 | 188
Mental Depression 2 | 333
Polycystic ovary syndrome 2 | 360
adult high grade glioma 2 | 3,801
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
psoriasis 2 | 6,694
ACTH-independent hypercortisolemia 1 | 4
Abnormal prolactin level 1 | 7
Abnormality of female external genitalia 1 | 8
Absent/hypoplastic paranasal sinuses 1 | 5
Acoustic neuroma 1 | 11
Acrodysostosis 1 | 12
Adrenal Hyperplasia, Congenital 1 | 9
Adrenal hyperplasia 1 | 13
Agitation 1 | 16
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Bacterial endocarditis 1 | 2
Calvarial hyperostosis 1 | 5
Carney complex 1 | 25
Cone-shaped epiphyses 1 | 24
Cone-shaped epiphyses of phalanges 1 | 15
Congenital hypoplasia of radius 1 | 23
Congenital hypothyroidism 1 | 26
Cushing Syndrome 1 | 3
Decreased circulating ACTH level 1 | 12
Delirium 1 | 10
Ectopic pregnancy 1 | 16
Embryo Loss 1 | 7
Enlarged polycystic ovaries 1 | 10
Enlargement of calvarial bones 1 | 5
Female Urogenital Diseases 1 | 18
Growth hormone excess 1 | 14
Hyperkyphosis 1 | 111
Hyperphosphatemia (disorder) 1 | 17
Hypocalcemia 1 | 32
Hypoplastic vertebral bodies 1 | 7
Increased circulating cortisol level 1 | 7
Increased ossification of calvarial bones 1 | 5
Increased serum parathyroid hormone 1 | 14
Isolated somatotropin deficiency 1 | 30
Kyphosis deformity of spine 1 | 114
Linear atrophy 1 | 15
Long hallux 1 | 5
Malocclusion 1 | 57
McCune Albright syndrome 1 | 19
Mongolian spot 1 | 4
Multiple Endocrine Neoplasia Type 1 1 | 29
Multiple endocrine neoplasia type 4 1 | 5
Multiple lentigines 1 | 10
Myxoma of heart 1 | 2
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Narrow interpedicular space 1 | 4
Neurilemmoma 1 | 23
Obesity, Abdominal 1 | 24
Paradoxical increased cortisol secretion on dexamethasone suppression test 1 | 2
Peutz-Jeghers syndrome 1 | 21
Pheochromocytoma 1 | 24
Pigmented micronodular adrenocortical disease 1 | 4
Pituitary growth hormone cell adenoma 1 | 8
Primary hypercorticolism 1 | 4
Primary pigmented nodular adrenocortical disease 1 | 13
Radial ray hypoplasia 1 | 23
Red hair 1 | 6
Relative short stature 1 | 13
SERUM PHOSPHATE ELEVATED 1 | 14
Senile lentigo 1 | 10
Sertoli cell tumor 1 | 9
Short hands 1 | 50
Short metatarsal 1 | 21
Short phalanx of finger 1 | 32
Short stature, mild 1 | 13
Short ulnae 1 | 24
Slender build 1 | 14
Spade-like hand 1 | 16
Spermatocytoma 1 | 2
Spinal canal stenosis 1 | 12
Thrombosis of cerebral veins 1 | 6
Thyroid Gland Follicular Adenoma 1 | 9
Thyroid carcinoma 1 | 5
Transient myeloproliferative syndrome 1 | 7
ULNAR HYPOPLASIA 1 | 24
blue iris (physical finding) 1 | 17

Tissue

Endocrine System 7 | 18,159
Male tissues 6 | 17,142
Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Skin and soft tissues 5 | 17,230
Cardiovascular System 4 | 15,192
Liver and Pancreas 4 | 16,750
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Urinary Tract 4 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

negative regulation of meiotic... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
F-box only protein 43 FBXO43 Tbio Non-IDG -1.39476 25.9 94
F-box only protein 5 FBXO5 Tbio Non-IDG -1.71993 56.0 137
Nanos homolog 2 NANOS2 Tbio Non-IDG -1.57901 37.3 196
Oncostatin-M OSM Tbio Non-IDG -2.54044 421.5 433
cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A Tbio Enzyme -2.37476 257.4 258