Development Level

Tbio 23 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613

IMPC Phenotype

enlarged heart 3 | 210
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
small superior vagus ganglion 2 | 74
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hydroencephaly 1 | 14
hydrometra 1 | 53
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46

Disease

psoriasis 16 | 6,694
Cancer 15 | 2,499
Carcinoma 13 | 11,493
lung carcinoma 13 | 2,843
non-small cell lung cancer 11 | 2,890
ovarian cancer 11 | 8,520
Rheumatoid arthritis 10 | 1,191
lung cancer 10 | 4,740
osteosarcoma 10 | 7,950
tuberculosis 10 | 2,010
Asthma 9 | 385
Hypersensitivity reaction type II disease 9 | 253
glioblastoma 9 | 5,792
lung adenocarcinoma 9 | 2,716
diabetes mellitus 8 | 1,728
interstitial cystitis 8 | 2,312
sarcoidosis 8 | 370
Allergic hypersensitivity disease 7 | 126
Allergic rhinitis 7 | 94
Breast cancer 7 | 3,578
Multiple Sclerosis 7 | 540
Systemic lupus erythematosus 7 | 194
group 3 medulloblastoma 7 | 4,104
medulloblastoma, large-cell 7 | 6,241
Arthritis 6 | 290
Astrocytoma, Pilocytic 6 | 3,081
Hepatitis B 6 | 108
Narcolepsy 6 | 72
Narcolepsy-cataplexy 6 | 21
Schizophrenia 6 | 1,160
malignant mesothelioma 6 | 3,232
nasopharyngeal carcinoma 6 | 1,058
pancreatic cancer 6 | 2,398
ulcerative colitis 6 | 1,819
Berylliosis 5 | 28
Bipolar Disorder 5 | 666
Dermatitis 5 | 157
Diffuse cutaneous systemic sclerosis 5 | 17
Hypereosinophilic syndrome 5 | 71
Inflammation 5 | 120
Liver disease 5 | 237
Multiple Sclerosis, Susceptibility to 5 | 15
Rheumatoid Arthritis, Systemic Juvenile 5 | 16
Sarcoidosis 1 5 | 14
Vasculitis 5 | 80
adrenocortical carcinoma 5 | 1,428
follicular lymphoma 5 | 20
invasive ductal carcinoma 5 | 2,951
limited scleroderma 5 | 19
Arthritis, Rheumatoid 4 | 174
Brain disease 4 | 96
Common cold 4 | 67
Fever 4 | 138
Human immunodeficiency virus infectious disease 4 | 138
Inflammatory bowel disease 4 | 151
Liver Cirrhosis, Experimental 4 | 769
Lung disease 4 | 142
Pancreatitis 4 | 123
Type 1 diabetes mellitus 4 | 109
Uveitis 4 | 103
Vascular disease 4 | 319
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Abnormal blistering of the skin 3 | 54
Adult T-Cell Lymphoma/Leukemia 3 | 30
Alzheimer's disease 3 | 658
Arthralgia 3 | 90
Atherosclerosis 3 | 291
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Chronic obstructive pulmonary disease 3 | 184
Crohn Disease 3 | 45
Diarrhea 3 | 253
Fatigue 3 | 182
Kidney disease 3 | 430
Leishmaniasis 3 | 47
Leukemia-Lymphoma, Adult T-Cell 3 | 30
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Lupus Erythematosus, Systemic 3 | 67
Malaria 3 | 160
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Myocardial Infarction 3 | 151
Nausea and vomiting 3 | 97
Parasitic helminthiasis infectious disease 3 | 15
Peritonitis 3 | 43
Pneumonia 3 | 174
Skin bulla 3 | 54
Thrombocytopenia 3 | 197
adult high grade glioma 3 | 3,801
fibroadenoma 3 | 559
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Skin and soft tissues 26 | 17,230
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Nervous System 23 | 16,725
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 24 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145
Kinase 1 | 634
Nuclear Receptor 1 | 48

GO Process

negative regulation of interfe... 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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