Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
edema 1 | 59
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
microphthalmia 1 | 26
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 16 | 7,950
ovarian cancer 16 | 8,520
group 3 medulloblastoma 15 | 4,104
Carcinoma 14 | 11,493
lung cancer 12 | 4,740
psoriasis 12 | 6,694
Cancer 10 | 2,499
malignant mesothelioma 10 | 3,232
glioblastoma 9 | 5,792
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
non-small cell lung cancer 7 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Pick disease 5 | 1,894
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
pancreatic cancer 5 | 2,398
pediatric high grade glioma 5 | 1,064
primitive neuroectodermal tumor 5 | 3,035
Breast Neoplasms 4 | 445
MYELODYSPLASTIC SYNDROME 4 | 53
Mammary Neoplasms 4 | 425
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
hepatocellular carcinoma 4 | 547
lung carcinoma 4 | 2,843
tuberculosis 4 | 2,010
Autism Spectrum Disorders 3 | 75
Autism spectrum disorder 3 | 101
Big calvaria 3 | 147
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Intellectual disability 3 | 1,016
Multiple myeloma 3 | 1,332
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
ependymoma 3 | 4,679
immunodeficiency-centromeric instability-facial anomalies syndrome 3 | 16
inflammatory breast cancer 3 | 286
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
oligodendroglioma 3 | 2,850
pancreatic carcinoma 3 | 562
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acute myeloid leukemia, disease 2 | 30
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Cataract 7 2 | 32
Clear-cell metastatic renal cell carcinoma 2 | 4
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital Epicanthus 2 | 177
Craniofacial Abnormalities 2 | 151
Crohn's disease 2 | 321
Dementia 2 | 175
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dull intelligence 2 | 645
Endometrial Neoplasms 2 | 55
Glioma 2 | 74
Global developmental delay 2 | 608
Hypoplastic mandible condyle 2 | 275
Immune system cancer 2 | 140
Juvenile Myelomonocytic Leukemia 2 | 21
Leukemia, Myelomonocytic, Juvenile 2 | 20
Low intelligence 2 | 645
Lymphoid leukemia 2 | 160
Mandibular hypoplasia 2 | 275
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Myelodysplastic Syndromes 2 | 26
Poor school performance 2 | 645
Round face 2 | 45
Round, full face 2 | 45
Stomach Neoplasms 2 | 300
Tall stature 2 | 34
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
cutaneous lupus erythematosus 2 | 1,057
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
non-small cell lung carcinoma 2 | 317
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Non-IDG 14 | 12,091
Epigenetic 6 | 242
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
TF/Epigenetic 1 | 38

GO Process

negative regulation of gene ex... 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
PHD finger protein 1 PHF1 Tbio Epigenetic -2.14039 127.5 199
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Enhancer of polycomb homolog 1 EPC1 Tbio Non-IDG -1.32335 19.2 62
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95
Protein Jumonji JARID2 Tbio TF/Epigenetic -1.80136 65.3 135
CREB/ATF bZIP transcription factor CREBZF Tbio Transcription Factor -0.98570 10.9 153
DNA (cytosine-5)-methyltransferase 3B DNMT3B Tchem Epigenetic -2.73137 480.9 350
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.52798 33.0 172
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.91291 722.8 693