Development Level

Tbio 22 | 11,445
Tchem 6 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal heart morphology 2 | 162
decreased circulating alanine ... 2 | 47
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased neutrophil cell numb... 2 | 46
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal iris morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal seminal vesicle morph... 1 | 114
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased erythrocyte cell num... 1 | 39
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

ovarian cancer 18 | 8,520
Carcinoma 17 | 11,493
psoriasis 17 | 6,694
Cancer 16 | 2,499
osteosarcoma 14 | 7,950
lung cancer 13 | 4,740
glioblastoma 12 | 5,792
Breast cancer 9 | 3,578
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
malignant mesothelioma 9 | 3,232
medulloblastoma, large-cell 9 | 6,241
subependymal giant cell astrocytoma 9 | 2,287
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Adenoma 6 | 167
Astrocytoma, Pilocytic 6 | 3,081
Intellectual disability 6 | 1,016
Prostatic Neoplasms 6 | 495
acute myeloid leukemia 6 | 783
astrocytic glioma 6 | 2,597
Breast Neoplasms 5 | 445
Dull intelligence 5 | 645
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Mammary Neoplasms 5 | 425
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Myocardial Infarction 5 | 151
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
diabetes mellitus 5 | 1,728
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Autistic Disorder 4 | 364
Autosomal recessive predisposition 4 | 1,442
Cognitive delay 4 | 608
Colonic Neoplasms 4 | 142
Congenital Epicanthus 4 | 177
Glioma 4 | 74
Global developmental delay 4 | 608
Hypertensive disease 4 | 292
Kidney disease 4 | 430
Mental and motor retardation 4 | 608
Mesothelioma, Malignant 4 | 105
Multiple myeloma 4 | 1,332
Sarcoma 4 | 62
Short stature 4 | 531
Stomach Neoplasms 4 | 300
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 547
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Bipolar Disorder 3 | 666
Broad flat nasal bridge 3 | 236
Carcinoma, Hepatocellular 3 | 228
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hypertension 3 | 396
Immune system cancer 3 | 140
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Multiple Sclerosis 3 | 540
Nasal bridge wide 3 | 236
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Seizures 3 | 596
Unipolar Depression 3 | 250
Vascular disease 3 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074

Tissue

Endocrine System 29 | 18,159
Urinary Tract 29 | 16,678
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725

Target Family

Non-IDG 20 | 12,091
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

negative regulation of fibrobl... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mediator of RNA polymerase II transcription subunit 31 MED31 Tbio Enzyme -1.19048 15.1 61
Emerin EMD Tbio Non-IDG -2.80459 640.6 299
Mediator of RNA polymerase II transcription subunit 25 MED25 Tbio Enzyme -1.76765 57.1 86
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
NLR family CARD domain-containing protein 3 NLRC3 Tbio Non-IDG 0.00000 29
Poly [ADP-ribose] polymerase 10 PARP10 Tchem Enzyme -1.07289 14.2 67
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
PRKC apoptosis WT1 regulator protein PAWR Tbio Non-IDG -1.93678 105.8 292
MORC family CW-type zinc finger protein 3 MORC3 Tbio Non-IDG -1.61241 36.6 61
Beta-1,4-galactosyltransferase 7 B4GALT7 Tbio Enzyme -1.56894 38.8 65