Development Level

Tbio 21 | 10,625
Tchem 6 | 1,890
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
decreased circulating alanine ... 2 | 53
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal motor capabilities/co... 1 | 4
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased lactate dehydrogenas... 1 | 14
decreased monocyte cell number 1 | 28
decreased spleen weight 1 | 13
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased eosinophil cell numb... 1 | 9
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased neutrophil cell numb... 1 | 15
increased startle reflex 1 | 38
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

ovarian cancer 18 | 8,484
psoriasis 18 | 6,685
Cancer 14 | 2,346
lung cancer 14 | 4,466
osteosarcoma 13 | 7,933
glioblastoma 10 | 5,572
atypical teratoid / rhabdoid tumor 9 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
medulloblastoma, large-cell 9 | 6,234
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
malignant mesothelioma 8 | 3,162
subependymal giant cell astrocytoma 8 | 2,287
Adenoma 6 | 165
Breast cancer 6 | 3,094
Prostatic Neoplasms 6 | 471
acute myeloid leukemia 6 | 780
adrenocortical carcinoma 6 | 1,427
posterior fossa group A ependymoma 6 | 1,511
ulcerative colitis 6 | 2,087
Lung Neoplasms 5 | 171
Mammary Neoplasms 5 | 410
Rheumatoid Arthritis 5 | 1,160
astrocytoma 5 | 1,493
diabetes mellitus 5 | 1,663
group 4 medulloblastoma 5 | 1,875
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,713
non-small cell lung cancer 5 | 2,798
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pediatric high grade glioma 5 | 2,712
pilocytic astrocytoma 5 | 3,086
primitive neuroectodermal tumor 5 | 3,031
Colonic Neoplasms 4 | 126
Glioma 4 | 65
Kidney disease 4 | 396
Multiple myeloma 4 | 1,327
Myocardial Infarction 4 | 126
Sarcoma 4 | 49
Stomach Neoplasms 4 | 282
astrocytic glioma 4 | 2,241
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 2,514
hepatocellular carcinoma 4 | 532
lung carcinoma 4 | 2,844
nasopharyngeal carcinoma 4 | 1,056
oligodendroglioma 4 | 2,849
pancreatic carcinoma 4 | 567
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,557
Acquired immunodeficiency syndrome 3 | 164
Acute kidney injury 3 | 65
Asthma 3 | 349
Autistic Disorder 3 | 320
Bladder Neoplasm 3 | 109
Chronic Lymphocytic Leukemia 3 | 242
Diabetes Mellitus, Experimental 3 | 106
Down syndrome 3 | 548
Drug-Induced Liver Injury 3 | 118
Intellectual disability 3 | 573
Leukemia, Myelocytic, Acute 3 | 113
Liver Neoplasms, Experimental 3 | 48
Liver carcinoma 3 | 217
Liver disease 3 | 219
Melanoma 3 | 261
Multiple Sclerosis 3 | 498
Neoplasm Metastasis 3 | 138
Peripheral Neuropathy 3 | 303
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 332
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,157
cutaneous lupus erythematosus 3 | 1,056
cystic fibrosis 3 | 1,665
glioblastoma multiforme 3 | 347
group 3 medulloblastoma 3 | 2,254
interstitial cystitis 3 | 2,299
non-small cell lung carcinoma 3 | 413
spina bifida 3 | 1,064
Allergic hypersensitivity disease 2 | 123
Amyotrophic Lateral Sclerosis 2 | 431
Atherosclerosis 2 | 275
Coronary artery disease 2 | 240
Crohn Disease 2 | 97
Dermatitis 2 | 107
Dermatitis, Allergic Contact 2 | 66
Disease Progression 2 | 125
Heart disease 2 | 279
Hypersensitivity reaction type II disease 2 | 235
Hypertensive disease 2 | 193
Lung disease 2 | 132
Male infertility 2 | 170
Neurodegenerative disease 2 | 383
Neuropathy 2 | 210
Pancreatic Neoplasm 2 | 79
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
breast carcinoma 2 | 1,614
chronic rhinosinusitis 2 | 512

Tissue

Cardiovascular System 29 | 17,958
Digestive Tract 29 | 18,473
Endocrine System 29 | 18,512
Female tissues 29 | 18,647
Liver and Pancreas 29 | 18,136
Nervous System 29 | 18,561
Urinary Tract 29 | 18,444
Male tissues 28 | 17,969
Respiratory system 28 | 17,484
Skin and soft tissues 28 | 18,115
Blood and immune system 27 | 17,995

Target Family

Non-IDG 19 | 11,971
Enzyme 7 | 4,146
Transcription Factor 2 | 1,400
GPCR 1 | 406

GO Process

negative regulation of fibrobl... 29 | 29
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphotoxin-alpha LTA Tbio Non-IDG -2.84770 612.8 461
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435
Complement C1q-like protein 4 C1QL4 Tdark Non-IDG -0.02576 1.67 46
Interferon gamma IFNG Tbio Non-IDG -3.87939 5432.4 1711
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.66052 440.9 327
Poly [ADP-ribose] polymerase 10 PARP10 Tchem Enzyme -0.99096 14.1 53
Gamma-interferon-inducible lysosomal thiol reductase IFI30 Tbio Enzyme -2.10661 141.4 103
Mediator of RNA polymerase II transcription subunit 25 MED25 Tbio Enzyme -1.73819 56.0 62
Parafibromin CDC73 Tbio Non-IDG -2.37301 260.4 168