Development Level

Tbio 19 | 10,625
Tchem 16 | 1,890
Tclin 2 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 633
increased bone mineral content 2 | 92
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 51
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
increased heart weight 1 | 37
increased lean body mass 1 | 107

Disease

ovarian cancer 31 | 8,491
Cancer 22 | 2,346
osteosarcoma 22 | 7,933
psoriasis 21 | 6,685
glioblastoma 20 | 5,572
atypical teratoid / rhabdoid tumor 17 | 4,369
medulloblastoma, large-cell 16 | 6,234
lung cancer 15 | 4,473
Breast cancer 14 | 3,098
malignant mesothelioma 14 | 3,163
lung carcinoma 12 | 2,844
group 4 medulloblastoma 11 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
Carcinoma 10 | 2,147
diabetes mellitus 10 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
Mammary Neoplasms 9 | 410
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
pancreatic cancer 9 | 2,300
pediatric high grade glioma 9 | 2,712
pilocytic astrocytoma 9 | 3,086
acute quadriplegic myopathy 8 | 1,157
astrocytic glioma 8 | 2,241
ependymoma 8 | 2,514
non-small cell lung cancer 8 | 2,798
pituitary cancer 8 | 1,972
tuberculosis 8 | 1,563
Amyotrophic Lateral Sclerosis 7 | 432
Pick disease 7 | 1,893
colon cancer 7 | 1,475
interstitial cystitis 7 | 2,299
invasive ductal carcinoma 7 | 2,950
primitive neuroectodermal tumor 7 | 3,031
subependymal giant cell astrocytoma 7 | 2,287
Osteoporosis 6 | 259
adrenocortical carcinoma 6 | 1,427
astrocytoma 6 | 1,493
oligodendroglioma 6 | 2,849
posterior fossa group A ependymoma 6 | 1,511
ulcerative colitis 6 | 2,087
Alzheimer's disease 5 | 644
Autistic Disorder 5 | 320
Drug-Induced Liver Injury 5 | 118
Hypertensive disease 5 | 193
Kidney disease 5 | 397
Neurodegenerative disease 5 | 383
Polycystic Ovary Syndrome 5 | 334
Rheumatoid Arthritis 5 | 1,170
aldosterone-producing adenoma 5 | 664
cutaneous lupus erythematosus 5 | 1,056
cystic fibrosis 5 | 1,670
group 3 medulloblastoma 5 | 2,254
juvenile dermatomyositis 5 | 1,189
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
Colitis 4 | 46
Duchenne muscular dystrophy 4 | 602
Multiple myeloma 4 | 1,327
Prostatic Neoplasms 4 | 471
Vascular disease 4 | 281
adult high grade glioma 4 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
lung adenocarcinoma 4 | 2,714
mucosa-associated lymphoid tissue lymphoma 4 | 480
posterior fossa group B ependymoma 4 | 1,530
sonic hedgehog group medulloblastoma 4 | 1,482
spina bifida 4 | 1,064
Adenoma 3 | 165
Arthritis 3 | 248
Atopic dermatitis 3 | 944
Bladder Neoplasm 3 | 109
Colonic Neoplasms 3 | 126
Colorectal Neoplasms 3 | 217
Endometriosis 3 | 535
Heart disease 3 | 279
Juvenile arthritis 3 | 124
Liver carcinoma 3 | 217
Muscular atrophy 3 | 67
Myocardial Ischemia 3 | 169
Neoplasm Invasiveness 3 | 127
Neuropathy 3 | 210
Obesity 3 | 616
Peripheral Neuropathy 3 | 303
Prostate cancer 3 | 172
Pulmonary Fibrosis 3 | 66
Spontaneous abortion 3 | 108
Toxic encephalopathy 3 | 131
active ulcerative colitis 3 | 477
breast carcinoma 3 | 1,614
hepatocellular carcinoma 3 | 550
hereditary spastic paraplegia 3 | 313
pancreatic carcinoma 3 | 567
primary Sjogren syndrome 3 | 788
Hyperandrogenism 2 | 32
Leukemia 2 | 88
Type 2 diabetes mellitus 2 | 192

Tissue

Blood and immune system 37 | 17,994
Cardiovascular System 37 | 17,957
Digestive Tract 37 | 18,472
Endocrine System 37 | 18,511
Female tissues 37 | 18,646
Liver and Pancreas 37 | 18,135
Male tissues 37 | 17,968
Nervous System 37 | 18,560
Respiratory system 37 | 17,483
Skin and soft tissues 37 | 18,114
Urinary Tract 37 | 18,443

Target Family

Non-IDG 19 | 11,969
Enzyme 7 | 4,146
Kinase 6 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48

GO Process

negative regulation of extrins... 37 | 37
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
E3 ubiquitin-protein ligase SIAH2 SIAH2 Tbio Enzyme -1.77545 62.6 155
Transcription factor 7-like 2 TCF7L2 Tbio Transcription Factor -2.60797 439.7 281
Thrombospondin-1 THBS1 Tbio Non-IDG -3.04674 1192.7 409
Baculoviral IAP repeat-containing protein 6 BIRC6 Tbio Non-IDG -1.75274 58.1 159
Androgen receptor AR Tclin Nuclear Receptor -3.79989 6683.7 1366
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.92178 654.5 340
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -3.98540 8801.0 1257
Glutathione S-transferase P GSTP1 Tchem Enzyme -3.18520 1707.5 450