Development Level

Tbio 17 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

abnormal heart morphology 3 | 162
decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart looping 1 | 5
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal lymph node morphology 1 | 3
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal tail bud morphology 1 | 8
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased body temperature 1 | 2
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased leukocyte cell numbe... 1 | 73
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased or absent threshold ... 1 | 101
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36

Disease

Carcinoma 14 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 11 | 8,520
lung cancer 9 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
psoriasis 8 | 6,694
Cancer 7 | 2,499
ependymoma 7 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
glioblastoma 6 | 5,792
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
ulcerative colitis 6 | 1,819
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
Kidney disease 5 | 430
adrenocortical carcinoma 5 | 1,428
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
Heart disease 3 | 306
Hereditary hemorrhagic telangiectasia 3 | 13
Liver Cirrhosis 3 | 181
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
head and neck cancer 3 | 271
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
Acquired metabolic disease 2 | 336
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Cerebrovascular disease 2 | 238
Cholecystitis 2 | 18
Congenital heart disease 2 | 93
Diabetic Angiopathies 2 | 16
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Epilepsy 2 | 792
Epistaxis 2 | 43
Eye disease 2 | 62
Fibrosis 2 | 44
Hemangioma, Cavernous 2 | 20
Hypertension 2 | 396
Hypertension, Portal 2 | 22
Hypertension, Pulmonary 2 | 37
Intermittent migraine headaches 2 | 68
Iron-Refractory Iron Deficiency Anemia 2 | 15
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Migraine Disorders 2 | 76
Nephritis, Interstitial 2 | 10
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Pulmonary embolism 2 | 55
Seizures 2 | 596
Spontaneous haematoma 2 | 8
Spontaneous, recurrent epistaxis 2 | 3
Telangiectasia of the skin 2 | 39
Telangiectasia, Hereditary Hemorrhagic 2 | 3
Telangiectasis 2 | 36
Tetralogy of Fallot 2 | 63
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
Visceral angiomatosis 2 | 13
active Crohn's disease 2 | 922
adrenocortical adenoma 2 | 131
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
glioblastoma multiforme 2 | 142
interstitial lung disease 2 | 298
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
pulmonary arterial hypertension 2 | 75
subependymal giant cell astrocytoma 2 | 2,287
Uveitis 1 | 103

Tissue

Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Digestive Tract 19 | 17,369
Blood and immune system 18 | 16,909
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 2 | 4,145
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GO Process

negative regulation of endothe... 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Receptor-type tyrosine-protein phosphatase mu PTPRM Tchem Enzyme -1.84748 71.7 144
Stanniocalcin-1 STC1 Tbio Non-IDG -2.88941 780.1 269
Adhesion G protein-coupled receptor B1 ADGRB1 Tbio GPCR -1.55248 42.8 267
A disintegrin and metalloproteinase with thrombospondin motifs 9 ADAMTS9 Tbio Enzyme -1.58561 39.6 48
Small vasohibin-binding protein SVBP Tdark Non-IDG -0.46982 3.42 43
Bone morphogenetic protein 10 BMP10 Tbio Non-IDG -1.43436 26.2 268
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Slit homolog 2 protein SLIT2 Tbio Non-IDG -2.01765 104.0 215
COUP transcription factor 2 NR2F2 Tbio Nuclear Receptor -2.18259 174.2 204