Development Level

Tbio 8 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal sleep behavior 1 | 70
decreased circulating phosphat... 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 9 | 11,493
medulloblastoma, large-cell 9 | 6,241
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
Astrocytoma, Pilocytic 6 | 3,081
malignant mesothelioma 6 | 3,232
osteosarcoma 6 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
astrocytic glioma 4 | 2,597
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Neurodegenerative disease 3 | 414
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Autosomal recessive predisposition 2 | 1,442
Charcot-Marie-Tooth disease 2 | 62
Kidney disease 2 | 430
Liver cancer 2 | 604
Motor delay 2 | 147
Neuropathy 2 | 261
No development of motor milestones 2 | 147
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
Abortion, Spontaneous 1 | 109
Acquired metabolic disease 1 | 336
Acquired scoliosis 1 | 281
Adenocarcinoma 1 | 122
Adenoma 1 | 167
Allergic hypersensitivity disease 1 | 126
Atherosclerosis 1 | 291
Atopic dermatitis 1 | 952
Autism spectrum disorder 1 | 101
Autistic Disorder 1 | 364
Bell Palsy 1 | 58
Chemical and Drug Induced Liver Injury 1 | 195
Colorectal Neoplasms 1 | 243
Congenital clubfoot 1 | 109
Coronary artery disease 1 | 268
Curvature of spine 1 | 282
Decreased tendon reflex 1 | 122
Distal amyotrophy 1 | 51
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Distal sensory impairment 1 | 52
Dysarthria 1 | 192
Epilepsy 1 | 792
Esophageal Neoplasms 1 | 69
Facial Paresis 1 | 59
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Heart disease 1 | 306
Huntington's disease 1 | 76
Hyperreflexia 1 | 209
Hypertension 1 | 396
Lactose intolerance 1 | 7
Leptospirosis 1 | 18
Liver Cirrhosis, Experimental 1 | 769
Lung disease 1 | 142
Melanoma 1 | 711
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Oculocerebrorenal syndrome 1 | 29
Orofacial cleft 1 | 54
Progressive disorder 1 | 142
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Salivary Gland Neoplasms 1 | 46
Seizures 1 | 596
Skin cancer 1 | 469
Spinocerebellar Ataxias 1 | 34
Spontaneous abortion 1 | 113
Stomach Neoplasms 1 | 300
Type 2 diabetes mellitus 1 | 272
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298
sarcoidosis 1 | 370
tuberculosis 1 | 2,010

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 5 | 4,145
Kinase 2 | 634

GO Process

negative regulation of endocyt... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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