Development Level

Tbio 18 | 11,651
Tchem 5 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased circulating alanine ... 2 | 47
enlarged heart 2 | 210
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased circulating bilirubi... 1 | 16
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

Cancer 15 | 2,499
Carcinoma 15 | 11,493
ovarian cancer 13 | 8,520
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
lung cancer 10 | 4,740
malignant mesothelioma 8 | 3,232
invasive ductal carcinoma 7 | 2,951
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
non-small cell lung cancer 6 | 2,890
Adenoma 5 | 167
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
Abdominal pain, episodic 4 | 9
Acromegaly 4 | 51
Adrenal cortical adenoma 4 | 19
Angiofibroma 4 | 7
Diarrhea 4 | 253
Esophagitis 4 | 35
Growth hormone excess 4 | 14
Hypercalcemia 4 | 59
Hyperinsulinaemic hypoglycaemia 4 | 16
Hyperinsulinemia, fasting 4 | 7
Hyperparathyroidism 4 | 48
Immune system cancer 4 | 140
Increased serum parathyroid hormone 4 | 14
Insulinoma 4 | 24
Multiple Endocrine Neoplasia Type 1 4 | 29
Non-Functioning Pituitary Gland Neoplasm 4 | 6
Parathyroid Adenoma 4 | 19
Parathyroid hyperplasia 4 | 6
Peptic Ulcer 4 | 27
Pituitary growth hormone cell adenoma 4 | 8
Prolactinoma 4 | 11
Subcutaneous lipomas 4 | 9
Thyroid Gland Follicular Adenoma 4 | 9
Zollinger-Ellison syndrome 4 | 18
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
ependymoma 4 | 4,679
intermittent abdominal pain 4 | 9
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Carcinoma, Hepatocellular 3 | 228
Intestinal Neoplasms 3 | 12
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Lymphoid leukemia 3 | 160
Melanoma 3 | 711
Multiple endocrine neoplasia type 4 3 | 5
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Atherosclerosis 2 | 291
Cerebrovascular disease 2 | 238
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Duchenne muscular dystrophy 2 | 601
Endometriosis 2 | 540
Heart disease 2 | 306
Inflammatory bowel disease 2 | 151
Multiple Sclerosis 2 | 540
Neuroendocrine Tumors 2 | 11
Pituitary adenoma 2 | 38
Reperfusion Injury 2 | 86
Schizophrenia 2 | 1,160
active ulcerative colitis 2 | 764
cystic fibrosis 2 | 1,696
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GO Process

negative regulation of cyclin-... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor AP-4 TFAP4 Tbio Transcription Factor -1.33384 19.4 276
CDK5 regulatory subunit-associated protein 1 CDK5RAP1 Tbio Non-IDG -1.30040 19.0 133
Protein HEXIM1 HEXIM1 Tbio Non-IDG -1.82459 64.7 348
F-box only protein 7 FBXO7 Tbio Non-IDG -2.07231 118.6 100
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Serine/threonine-protein kinase LATS1 LATS1 Tbio Kinase -2.31749 179.0 253
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cyclin-dependent kinase 4 inhibitor C CDKN2C Tbio Enzyme -1.97718 112.7 386
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.09610 1271.1 856
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508