Development Level

Tbio 4 | 11,445

IMPC Phenotype

abnormal heart morphology 2 | 162
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased circulating insulin ... 1 | 76
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Cancer 3 | 2,499
Hypercalcemia 3 | 59
Lung Neoplasms 3 | 232
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Abdominal pain, episodic 2 | 9
Acromegaly 2 | 51
Adenoma 2 | 167
Adrenal cortical adenoma 2 | 19
Angiofibroma 2 | 7
Breast cancer 2 | 3,578
Diarrhea 2 | 253
Esophagitis 2 | 35
Growth hormone excess 2 | 14
Hyperinsulinaemic hypoglycaemia 2 | 16
Hyperinsulinemia, fasting 2 | 7
Hyperparathyroidism 2 | 48
Increased serum parathyroid hormone 2 | 14
Insulinoma 2 | 24
Intestinal Neoplasms 2 | 12
Multiple Endocrine Neoplasia Type 1 2 | 29
Non-Functioning Pituitary Gland Neoplasm 2 | 6
Parathyroid Adenoma 2 | 19
Parathyroid hyperplasia 2 | 6
Peptic Ulcer 2 | 27
Pituitary growth hormone cell adenoma 2 | 8
Prolactinoma 2 | 11
Prostatic Neoplasms 2 | 495
Stomach Neoplasms 2 | 300
Subcutaneous lipomas 2 | 9
Thyroid Gland Follicular Adenoma 2 | 9
Zollinger-Ellison syndrome 2 | 18
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
gastric cancer 2 | 459
glioblastoma 2 | 5,792
head and neck cancer 2 | 271
intermittent abdominal pain 2 | 9
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
Adenocarcinoma 1 | 122
Adenoma, Liver Cell 1 | 8
Advanced bone age 1 | 35
Ataxia telangiectasia 1 | 34
Breast Neoplasms 1 | 445
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Chloracne 1 | 32
Coarse facial features 1 | 108
Common variable immunodeficiency 1 | 101
Endometrial Neoplasms 1 | 55
Esophageal Squamous Cell Carcinoma 1 | 77
Fetal overgrowth 1 | 16
Generalized overgrowth 1 | 16
Gonadoblastoma 1 | 34
HIV Infections 1 | 102
Heart conduction disease 1 | 83
Hepatoblastoma 1 | 19
Hydronephrosis 1 | 89
Hypercalciuria 1 | 27
Kidney Diseases 1 | 114
Kidney Neoplasm 1 | 29
Kidney Neoplasms 1 | 37
Mammary Neoplasms 1 | 425
Mesothelioma 1 | 38
Multiple endocrine neoplasia type 2A 1 | 20
Neonatal hypoglycemia 1 | 17
Nephroblastoma 1 | 51
Ovarian Neoplasms 1 | 102
Overgrowth 1 | 16
Papilloma 1 | 44
Penile hypospadias 1 | 106
Prominent back of the head 1 | 21
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prominent occiput 1 | 21
Prostatic Intraepithelial Neoplasia 1 | 11
Prostatic Intraepithelial Neoplasias 1 | 11
Protruding eyes 1 | 96
Retinopathy of prematurity 1 | 22
Sezary Syndrome 1 | 27
Silver-Russell syndrome 1 | 39
Small testicle 1 | 75
Squamous cell carcinoma of esophagus 1 | 77
Systemic lupus erythematosus 1 | 194
Thickened facial skin with coarse facial features 1 | 108
Wide bregma sutures 1 | 46
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 4 | 4,145

GO Process

negative regulation of cyclin-... 4 | 4
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
Calcium/calmodulin-dependent protein kinase II inhibitor 1 CAMK2N1 Tbio Enzyme -0.51423 3.98 64
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509
Cyclin-dependent kinase inhibitor 1B CDKN1B Tbio Enzyme -3.11753 1246.6 1886