Development Level

Tbio 6 | 10,625
Tchem 3 | 1,890
Tclin 2 | 602

IMPC Phenotype

abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
decreased rib number 1 | 59
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260

Disease

Cancer 9 | 2,346
lung cancer 7 | 4,473
osteosarcoma 7 | 7,933
ovarian cancer 7 | 8,491
medulloblastoma, large-cell 6 | 6,234
psoriasis 6 | 6,685
Breast cancer 4 | 3,098
Carcinoma 4 | 2,147
atypical teratoid/rhabdoid tumor 4 | 1,095
breast carcinoma 4 | 1,614
glioblastoma 4 | 5,572
group 3 medulloblastoma 4 | 2,254
invasive ductal carcinoma 4 | 2,950
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
Adenocarcinoma 3 | 115
Mammary Neoplasms 3 | 410
Prostatic Neoplasms 3 | 471
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
atypical teratoid / rhabdoid tumor 3 | 4,369
ependymoma 3 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
primary pancreatic ductal adenocarcinoma 3 | 1,271
primitive neuroectodermal tumor 3 | 3,031
Adenocarcinoma of lung (disorder) 2 | 48
Brain infarction 2 | 17
Chronic obstructive pulmonary disease 2 | 147
Colorectal Neoplasms 2 | 217
Heart disease 2 | 279
Leukemia, Myelocytic, Acute 2 | 113
Lung Neoplasms 2 | 171
Lymphoid leukemia 2 | 69
Malignant neoplasm of lung 2 | 16
Myeloid Leukemia, Chronic 2 | 22
Neoplasm Metastasis 2 | 138
Obesity 2 | 616
Pancreatic Neoplasm 2 | 79
Precursor Cell Lymphoblastic Leukemia Lymphoma 2 | 42
Rheumatoid Arthritis 2 | 1,170
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,714
lung carcinoma 2 | 2,844
ovarian neoplasm 2 | 97
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,563
ulcerative colitis 2 | 2,087
ADULT syndrome 1 | 9
Aplastic anemia 1 | 19
Aplastic anemia, idiopathic 1 | 4
Ataxia telangiectasia 1 | 32
Blastic phase chronic myeloid leukemia 1 | 58
Bone lymphoma 1 | 3
Brain Neoplasms 1 | 23
Carcinogenesis 1 | 6
Ceroid lipofuscinosis, neuronal 1, infantile 1 | 10
Chromosome Aberrations 1 | 15
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic eosinophilic leukemia 1 | 11
Chronic myeloid leukemia 1 | 11
Chronic phase chronic myeloid leukemia 1 | 45
Cri-Du-Chat syndrome 1 | 16
DNA ligase IV deficiency 1 | 6
DYSKERATOSIS CONGENITA, AUTOSOMAL DOMINANT 1 | 2
DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1 1 | 3
Dermatofibrosarcoma protuberans 1 | 16
Dyskeratosis congenita autosomal dominant 1 | 3
Dyskeratosis congenita autosomal recessive 1 1 | 3
Focal dermal hypoplasia 1 | 9
HOYERAAL-HREIDARSSON SYNDROME 1 | 7
Hemorrhagic disease 1 | 11
Hormone receptor positive malignant neoplasm of breast 1 | 10
Idiopathic hypereosinophilic syndrome 1 | 10
Idiopathic pulmonary fibrosis 1 | 21
Immunodeficiency 26 with or without neurologic abnormalities 1 | 1
Impaired glucose tolerance 1 | 12
Insulin Resistance 1 | 50
Ki-1+ Anaplastic Large Cell Lymphoma 1 | 4
Leukemia, Lymphocytic, Acute, L1 1 | 11
Lung Injury 1 | 20
Massive Hepatic Necrosis 1 | 1
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 1 | 9
Neurodegenerative Disorders 1 | 37
Nonsyndromic congenital nail disorder 1 1 | 3
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pulmonary Fibrosis, Idiopathic 1 | 12
Reticulosarcoma 1 | 6
Retinal Diseases 1 | 21
Systemic mast cell disease 1 | 12
Tyrosinemia type II 1 | 6
acute T cell leukemia 1 | 17
bladder exstrophy 1 | 12

Tissue

Blood and immune system 11 | 17,994
Cardiovascular System 11 | 17,957
Digestive Tract 11 | 18,472
Endocrine System 11 | 18,511
Female tissues 11 | 18,646
Liver and Pancreas 11 | 18,135
Male tissues 11 | 17,968
Nervous System 11 | 18,560
Respiratory system 11 | 17,483
Skin and soft tissues 11 | 18,114
Urinary Tract 11 | 18,443

Target Family

Transcription Factor 5 | 1,400
Kinase 3 | 634
Enzyme 1 | 4,146
Epigenetic 1 | 242
Non-IDG 1 | 11,969

GO Process

negative regulation of cellula... 11 | 11
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.67376 362.2 617
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.89181 7558.3 366
Tumor protein 63 TP63 Tbio Transcription Factor -3.02650 1176.3 410
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.43962 2958.6 656
Tyrosine-protein kinase ABL1 ABL1 Tclin Kinase -3.49571 3222.2 1533
Telomerase reverse transcriptase TERT Tchem Enzyme -3.54194 3297.5 585
Telomeric repeat-binding factor 2 TERF2 Tbio Transcription Factor -2.22569 167.7 314
DNA-dependent protein kinase catalytic subunit PRKDC Tchem Kinase -2.83885 693.7 1027
Zinc finger protein with KRAB and SCAN domains 3 ZKSCAN3 Tbio Transcription Factor -0.84291 9.15 85
B-cell lymphoma 6 protein BCL6 Tbio Transcription Factor -2.98669 987.9 369