Development Level

Tbio 291 | 11,445
Tchem 66 | 1,598
Tclin 33 | 613
Tdark 8 | 6,588

Collection

Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 38 | 979
abnormal behavior 10 | 298
preweaning lethality, incomple... 10 | 499
decreased body weight 8 | 161
increased lean body mass 8 | 172
abnormal lens morphology 7 | 81
decreased bone mineral density 7 | 126
decreased grip strength 7 | 116
decreased lean body mass 7 | 135
decreased total body fat amoun... 7 | 207
enlarged heart 7 | 210
cataract 6 | 92
decreased circulating glucose ... 6 | 126
decreased vertical activity 6 | 208
abnormal bone structure 5 | 187
abnormal heart morphology 5 | 162
decreased bone mineral content 5 | 151
embryonic lethality prior to o... 5 | 239
impaired glucose tolerance 5 | 75
increased circulating alkaline... 5 | 122
abnormal embryo size 4 | 220
abnormal gait 4 | 69
abnormal sleep behavior 4 | 70
decreased circulating choleste... 4 | 93
decreased circulating triglyce... 4 | 79
embryonic lethality prior to t... 4 | 278
increased blood urea nitrogen ... 4 | 48
increased fasted circulating g... 4 | 76
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
small superior vagus ganglion 4 | 74
thrombocytopenia 4 | 56
abnormal cranium morphology 3 | 36
abnormal facial morphology 3 | 17
abnormal testis morphology 3 | 43
decreased body length 3 | 101
decreased erythrocyte cell num... 3 | 62
decreased hemoglobin content 3 | 68
edema 3 | 59
hypoactivity 3 | 132
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased erythrocyte cell num... 3 | 39
increased mean corpuscular hem... 3 | 36
increased vertical activity 3 | 24
small testis 3 | 58
abnormal bone mineralization 2 | 38
abnormal eyelid fusion 2 | 3
abnormal head morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal lung morphology 2 | 26
abnormal retina morphology 2 | 71
abnormal retinal blood vessel ... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal vertebrae morphology 2 | 18
anophthalmia 2 | 33
decreased blood urea nitrogen ... 2 | 51
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased heart rate 2 | 18
decreased hematocrit 2 | 46
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
hemorrhage 2 | 23
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating calcium ... 2 | 34
increased circulating iron lev... 2 | 30
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
increased red blood cell distr... 2 | 34
male infertility 2 | 123
mammalian phenotype 2 | 17
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small kidney 2 | 16
thin skin 2 | 2
tremors 2 | 39
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal vocalization 1 | 21
decreased T cell number 1 | 15

Disease

Carcinoma 261 | 11,493
ovarian cancer 239 | 8,520
Cancer 198 | 2,499
psoriasis 197 | 6,694
lung cancer 176 | 4,740
osteosarcoma 172 | 7,950
medulloblastoma, large-cell 164 | 6,241
glioblastoma 163 | 5,792
atypical teratoid / rhabdoid tumor 136 | 5,112
ependymoma 131 | 4,679
Breast cancer 128 | 3,578
malignant mesothelioma 114 | 3,232
adult high grade glioma 109 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 106 | 2,955
invasive ductal carcinoma 106 | 2,951
group 3 medulloblastoma 100 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 98 | 3,291
pancreatic cancer 97 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 96 | 2,989
non-small cell lung cancer 93 | 2,890
lung carcinoma 91 | 2,843
oligodendroglioma 90 | 2,850
Astrocytoma, Pilocytic 89 | 3,081
lung adenocarcinoma 86 | 2,716
interstitial cystitis 82 | 2,312
primitive neuroectodermal tumor 80 | 3,035
astrocytic glioma 77 | 2,597
ductal carcinoma in situ 74 | 1,745
pituitary cancer 72 | 1,972
subependymal giant cell astrocytoma 72 | 2,287
tuberculosis 68 | 2,010
cystic fibrosis 66 | 1,696
Kidney cancer 65 | 2,613
ulcerative colitis 65 | 1,819
breast carcinoma 62 | 1,638
colon cancer 58 | 1,478
diabetes mellitus 58 | 1,728
group 4 medulloblastoma 57 | 1,855
Breast Neoplasms 56 | 445
Mammary Neoplasms 55 | 425
Schizophrenia 55 | 1,160
primary pancreatic ductal adenocarcinoma 53 | 1,109
Pick disease 50 | 1,894
acute quadriplegic myopathy 46 | 1,158
cutaneous lupus erythematosus 46 | 1,057
Autosomal recessive predisposition 45 | 1,442
astrocytoma 45 | 1,146
juvenile dermatomyositis 45 | 1,187
Rheumatoid arthritis 44 | 1,191
adrenocortical carcinoma 44 | 1,428
Multiple myeloma 42 | 1,332
Prostatic Neoplasms 41 | 495
dermatomyositis 41 | 966
Obesity 39 | 678
Liver Cirrhosis, Experimental 38 | 769
gastric carcinoma 38 | 807
pancreatic ductal adenocarcinoma liver metastasis 38 | 1,962
Seizures 37 | 596
Intellectual disability 36 | 1,016
Stomach Neoplasms 36 | 300
Alzheimer's disease 34 | 658
Epilepsy 33 | 792
autosomal dominant Emery-Dreifuss muscular dystrophy 33 | 510
Bipolar Disorder 32 | 666
fibroadenoma 32 | 559
Lung Neoplasms 31 | 232
Cognitive delay 30 | 608
Global developmental delay 30 | 608
Kidney disease 30 | 430
Melanoma 30 | 711
Mental and motor retardation 30 | 608
Short stature 30 | 531
non primary Sjogren syndrome sicca 30 | 891
pediatric high grade glioma 30 | 1,064
Hypertension 29 | 396
esophageal adenocarcinoma 29 | 737
Atopic dermatitis 28 | 952
Down syndrome 28 | 499
Dull intelligence 28 | 645
Endometriosis 28 | 540
Low intelligence 28 | 645
Mental Retardation 28 | 645
Mental deficiency 28 | 645
Poor school performance 28 | 645
Colorectal Neoplasms 27 | 243
Hypertensive disease 27 | 292
Vascular disease 27 | 319
active ulcerative colitis 27 | 764
spina bifida 27 | 1,074
Adenoma 26 | 167
Liver carcinoma 26 | 240
nasopharyngeal carcinoma 26 | 1,058
Carcinoma, Hepatocellular 25 | 228
Depressive disorder 25 | 409
Renal Cell Carcinoma 25 | 214
active Crohn's disease 25 | 922
acute myeloid leukemia 25 | 783
Duchenne muscular dystrophy 24 | 601
Muscle hypotonia 24 | 571
aldosterone-producing adenoma 24 | 665

Tissue

Endocrine System 389 | 18,159
Digestive Tract 388 | 17,369
Skin and soft tissues 387 | 17,230
Female tissues 383 | 17,400
Liver and Pancreas 381 | 16,750
Male tissues 381 | 17,142
Blood and immune system 380 | 16,909
Respiratory system 380 | 16,393
Urinary Tract 379 | 16,678
Nervous System 375 | 16,725
Cardiovascular System 351 | 15,192

Target Family

Non-IDG 199 | 12,091
Enzyme 64 | 4,145
Transcription Factor 64 | 1,400
Kinase 28 | 634
GPCR 18 | 408
Epigenetic 14 | 242
Nuclear Receptor 7 | 48
Transporter 2 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

GO Process

negative regulation of cell pr... 398 | 398
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoic acid receptor responder protein 3 RARRES3 Tbio Non-IDG -1.84020 71.0 164
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Growth arrest-specific protein 8 GAS8 Tbio Non-IDG -1.20822 17.3 102
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Relaxin receptor 2 RXFP2 Tbio GPCR -1.97913 85.3 207
Tetraspanin-32 TSPAN32 Tbio Non-IDG -0.97140 8.31 153
Protein BTG4 BTG4 Tbio Non-IDG -1.04941 12.0 112
Photoreceptor-specific nuclear receptor NR2E3 Tbio Nuclear Receptor 0.00000 261