Development Level

Tbio 76 | 11,445
Tchem 16 | 1,598
Tclin 4 | 613
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased body weight 6 | 161
decreased lean body mass 3 | 135
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased hematocrit 2 | 46
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal tail movements 1 | 12
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
head bobbing 1 | 5
hydroencephaly 1 | 14
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33

Disease

Carcinoma 71 | 11,493
ovarian cancer 68 | 8,520
osteosarcoma 56 | 7,950
psoriasis 51 | 6,694
medulloblastoma, large-cell 47 | 6,241
Cancer 45 | 2,499
glioblastoma 43 | 5,792
lung cancer 42 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
malignant mesothelioma 35 | 3,232
Breast cancer 34 | 3,578
atypical teratoid / rhabdoid tumor 34 | 5,112
lung carcinoma 34 | 2,843
pancreatic cancer 33 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
invasive ductal carcinoma 31 | 2,951
ependymoma 30 | 4,679
non-small cell lung cancer 29 | 2,890
oligodendroglioma 29 | 2,850
cystic fibrosis 28 | 1,696
lung adenocarcinoma 28 | 2,716
interstitial cystitis 27 | 2,312
adult high grade glioma 26 | 3,801
tuberculosis 25 | 2,010
pituitary cancer 24 | 1,972
Astrocytoma, Pilocytic 23 | 3,081
group 3 medulloblastoma 22 | 4,104
primary pancreatic ductal adenocarcinoma 22 | 1,109
primitive neuroectodermal tumor 22 | 3,035
subependymal giant cell astrocytoma 22 | 2,287
Kidney cancer 21 | 2,613
astrocytic glioma 21 | 2,597
breast carcinoma 21 | 1,638
colon cancer 20 | 1,478
ductal carcinoma in situ 19 | 1,745
juvenile dermatomyositis 19 | 1,187
ulcerative colitis 18 | 1,819
group 4 medulloblastoma 16 | 1,855
Pick disease 15 | 1,894
acute quadriplegic myopathy 15 | 1,158
dermatomyositis 15 | 966
esophageal adenocarcinoma 15 | 737
Atopic dermatitis 14 | 952
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
astrocytoma 13 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Prostatic Neoplasms 12 | 495
Rheumatoid arthritis 12 | 1,191
adrenocortical carcinoma 12 | 1,428
cutaneous lupus erythematosus 12 | 1,057
gastric carcinoma 12 | 807
Melanoma 11 | 711
active ulcerative colitis 11 | 764
diabetes mellitus 11 | 1,728
Hypertension 10 | 396
Multiple myeloma 10 | 1,332
Obesity 10 | 678
pediatric high grade glioma 10 | 1,064
Amyotrophic lateral sclerosis 9 | 451
Colorectal Neoplasms 9 | 243
Duchenne muscular dystrophy 9 | 601
active Crohn's disease 9 | 922
aldosterone-producing adenoma 9 | 665
fibroadenoma 9 | 559
nasopharyngeal carcinoma 9 | 1,058
urothelial carcinoma 9 | 318
Adenoma 8 | 167
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
Down syndrome 8 | 499
Hypertensive disease 8 | 292
Intellectual disability 8 | 1,016
Kidney disease 8 | 430
Liver cancer 8 | 604
Skin cancer 8 | 469
Barrett's esophagus 7 | 182
Breast Neoplasms 7 | 445
Heart disease 7 | 306
Liver Cirrhosis, Experimental 7 | 769
Mammary Neoplasms 7 | 425
Polycystic ovary syndrome 7 | 360
acute myeloid leukemia 7 | 783
mucosa-associated lymphoid tissue lymphoma 7 | 484
primary Sjogren syndrome 7 | 735
Hemangioma 6 | 69
Renal Cell Carcinoma 6 | 214
atypical teratoid/rhabdoid tumor 6 | 357
posterior fossa group A ependymoma 6 | 468
sarcoidosis 6 | 370
Atherosclerosis 5 | 291
Endometriosis 5 | 540
Epilepsy 5 | 792
Schizophrenia 5 | 1,160
Seizures 5 | 596
gastric cancer 5 | 459
hepatocellular carcinoma 5 | 547
pancreatic carcinoma 5 | 562
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074

Tissue

Digestive Tract 99 | 17,369
Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Liver and Pancreas 98 | 16,750
Skin and soft tissues 98 | 17,230
Blood and immune system 96 | 16,909
Male tissues 96 | 17,142
Respiratory system 96 | 16,393
Urinary Tract 96 | 16,678
Cardiovascular System 94 | 15,192
Nervous System 93 | 16,725

Target Family

Non-IDG 55 | 12,091
Enzyme 29 | 4,145
Kinase 5 | 634
Transcription Factor 5 | 1,400
GPCR 3 | 408
Epigenetic 1 | 242
Ion Channel 1 | 344
Transporter 1 | 473

GO Process

negative regulation of cell mi... 100 | 100
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Monoacylglycerol lipase ABHD6 ABHD6 Tchem Enzyme -1.37418 26.1 71
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
TRPM8 channel-associated factor 1 TCAF1 Tbio Enzyme 0.30 0.61 27
Tomoregulin-2 TMEFF2 Tbio Non-IDG -1.87758 86.0 194
Disintegrin and metalloproteinase domain-containing protein 15 ADAM15 Tbio Enzyme -1.87408 84.1 301
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Protein SCAI SCAI Tbio Non-IDG -2.49540 300.3 22