Development Level

Tbio 19 | 10,625
Tdark 19 | 7,003
Tchem 5 | 1,890
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 3 | 633
decreased body weight 2 | 174
abnormal QRS complex 1 | 25
abnormal cornea morphology 1 | 24
abnormal forced expiratory flo... 1 | 1
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
corneal opacity 1 | 25
decreased body temperature 1 | 2
decreased bone mineral content 1 | 157
decreased circulating free fat... 1 | 39
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased kidney weight 1 | 7
decreased lean body mass 1 | 195
decreased spleen weight 1 | 13
decreased tidal volume 1 | 1
embryonic lethality prior to t... 1 | 187
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased KLRG1-positive CD4-p... 1 | 2
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased grip strength 1 | 83
increased leukocyte cell numbe... 1 | 37
increased lymphocyte cell numb... 1 | 9
increased monocyte cell number 1 | 27
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
narrow eye opening 1 | 15

Disease

facioscapulohumeral dystrophy 18 | 286
Cancer 16 | 2,346
lung cancer 14 | 4,466
ovarian cancer 13 | 8,484
Breast cancer 12 | 3,094
osteosarcoma 12 | 7,933
psoriasis 12 | 6,685
medulloblastoma, large-cell 11 | 6,234
atypical teratoid / rhabdoid tumor 10 | 4,369
glioblastoma 9 | 5,572
invasive ductal carcinoma 9 | 2,950
lung adenocarcinoma 9 | 2,713
diabetes mellitus 8 | 1,663
group 3 medulloblastoma 8 | 2,254
pancreatic cancer 8 | 2,300
primitive neuroectodermal tumor 8 | 3,031
ependymoma 7 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
non-small cell lung cancer 7 | 2,798
pilocytic astrocytoma 7 | 3,086
lung carcinoma 6 | 2,844
medulloblastoma 6 | 1,524
oligodendroglioma 6 | 2,849
tuberculosis 6 | 1,557
Endometriosis 5 | 535
Multiple myeloma 5 | 1,327
Pick disease 5 | 1,893
acute quadriplegic myopathy 5 | 1,157
astrocytic glioma 5 | 2,241
cystic fibrosis 5 | 1,665
dermatomyositis 5 | 933
interstitial cystitis 5 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Adenoma 4 | 165
Cleft palate 4 | 125
Kidney disease 4 | 396
Mammary Neoplasms 4 | 410
Multiple Sclerosis 4 | 498
Neoplasm Metastasis 4 | 138
Rheumatoid Arthritis 4 | 1,160
Squamous cell carcinoma 4 | 94
adrenocortical carcinoma 4 | 1,427
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
juvenile dermatomyositis 4 | 1,189
malignant mesothelioma 4 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
ulcerative colitis 4 | 2,087
Alzheimer's disease 3 | 644
Amyotrophic Lateral Sclerosis 3 | 431
Arthritis 3 | 248
Cerebrovascular disease 3 | 231
Coronary artery disease 3 | 240
Crohn's disease 3 | 304
Hypospadias 3 | 65
Kidney Diseases 3 | 86
Lung Neoplasms 3 | 171
Malignant neoplasm of prostate 3 | 67
Neoplasm Invasiveness 3 | 127
Obesity 3 | 616
Prostatic Neoplasms 3 | 471
breast carcinoma 3 | 1,614
esophageal adenocarcinoma 3 | 737
non-small cell lung carcinoma 3 | 413
sarcoidosis 3 | 358
spina bifida 3 | 1,064
Alobar Holoprosencephaly 2 | 14
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Down syndrome 2 | 548
IGA Glomerulonephritis 2 | 454
Infertility 2 | 163
Juvenile arthritis 2 | 124
Liver carcinoma 2 | 217
Lobar Holoprosencephaly 2 | 14
Microcephaly 2 | 149
Microphthalmia 2 | 78
Osteoporosis 2 | 257
Pancreatic Neoplasm 2 | 79
Parkinson's disease 2 | 364
Peripheral vascular disease 2 | 90
Prostate cancer 2 | 172
SOLITARY MEDIAN MAXILLARY CENTRAL INCISOR 2 | 14
Semilobar Holoprosencephaly 2 | 14
Stomach Neoplasms 2 | 282
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
X-linked cerebral adrenoleukodystrophy 2 | 115
acute myeloid leukemia 2 | 780
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 557
inflammatory breast cancer 2 | 404
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
progressive supranuclear palsy 2 | 674

Tissue

Digestive Tract 37 | 18,473
Endocrine System 36 | 18,512
Liver and Pancreas 36 | 18,136
Female tissues 35 | 18,647
Urinary Tract 35 | 18,444
Skin and soft tissues 34 | 18,115
Blood and immune system 31 | 17,995
Nervous System 31 | 18,561
Male tissues 30 | 17,969
Cardiovascular System 28 | 17,958
Respiratory system 27 | 17,484

Target Family

Non-IDG 34 | 11,971
Transcription Factor 6 | 1,400
Kinase 2 | 634
Enzyme 1 | 4,146
Epigenetic 1 | 242
GPCR 1 | 406
Nuclear Receptor 1 | 48

GO Process

negative regulation of cell di... 46 | 46
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tchem Nuclear Receptor -2.70036 522.8 435
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.65911 362.2 617
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.94700 90.3 180
SKI family transcriptional corepressor 2 SKOR2 Tbio Non-IDG -0.50093 4.32 50
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -4.32707 20956.6 961
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.12872 1138.1 1044
PRAME family member 25 PRAMEF26 Tdark Non-IDG 0.00000 0
ETS-related transcription factor Elf-5 ELF5 Tbio Transcription Factor -1.68773 54.6 177