Development Level

Tbio 48 | 11,651
Tchem 8 | 1,388
Tclin 2 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
enlarged heart 3 | 210
hypoactivity 3 | 132
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
decreased body weight 2 | 161
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
increased mean corpuscular vol... 2 | 92
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal coat- hair morphology 1 | 19
abnormal eye morphology 1 | 68
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased aggression 1 | 4
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
mammalian phenotype 1 | 17
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97

Disease

ovarian cancer 40 | 8,520
Carcinoma 34 | 11,493
osteosarcoma 32 | 7,950
psoriasis 29 | 6,694
Cancer 26 | 2,499
lung cancer 26 | 4,740
medulloblastoma, large-cell 26 | 6,241
glioblastoma 25 | 5,792
atypical teratoid / rhabdoid tumor 21 | 5,112
ependymoma 20 | 4,679
Breast cancer 19 | 3,578
pancreatic cancer 19 | 2,398
malignant mesothelioma 18 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
invasive ductal carcinoma 16 | 2,951
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 15 | 4,104
primitive neuroectodermal tumor 15 | 3,035
non-small cell lung cancer 14 | 2,890
Schizophrenia 13 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
breast carcinoma 12 | 1,638
group 4 medulloblastoma 12 | 1,855
lung adenocarcinoma 12 | 2,716
oligodendroglioma 12 | 2,850
pituitary cancer 12 | 1,972
ductal carcinoma in situ 11 | 1,745
interstitial cystitis 11 | 2,312
Astrocytoma, Pilocytic 10 | 3,081
colon cancer 10 | 1,478
lung carcinoma 10 | 2,843
diabetes mellitus 9 | 1,728
nasopharyngeal carcinoma 9 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Alzheimer's disease 8 | 658
Autosomal recessive predisposition 8 | 1,442
Multiple myeloma 8 | 1,332
Osteoporosis 8 | 363
Rheumatoid arthritis 8 | 1,191
adrenocortical carcinoma 8 | 1,428
astrocytic glioma 8 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
primary pancreatic ductal adenocarcinoma 8 | 1,109
subependymal giant cell astrocytoma 8 | 2,287
Atherosclerosis 7 | 291
Kidney cancer 7 | 2,613
Kidney disease 7 | 430
acute quadriplegic myopathy 7 | 1,158
cutaneous lupus erythematosus 7 | 1,057
cystic fibrosis 7 | 1,696
dermatomyositis 7 | 966
ulcerative colitis 7 | 1,819
Atopic dermatitis 6 | 952
Heart disease 6 | 306
Liver Cirrhosis, Experimental 6 | 769
Neurodegenerative disease 6 | 414
Obesity 6 | 678
Osteoarthritis 6 | 184
Pick disease 6 | 1,894
Prostatic Neoplasms 6 | 495
Seizures 6 | 596
Vascular disease 6 | 319
astrocytoma 6 | 1,146
medulloblastoma 6 | 720
tuberculosis 6 | 2,010
Amyotrophic lateral sclerosis 5 | 451
Colorectal Neoplasms 5 | 243
Cryptorchidism 5 | 296
Duchenne muscular dystrophy 5 | 601
Dull intelligence 5 | 645
Hypertension 5 | 396
Intellectual disability 5 | 1,016
Liver Cirrhosis 5 | 181
Liver cancer 5 | 604
Low intelligence 5 | 645
Lung Neoplasms 5 | 232
Major Depressive Disorder 5 | 301
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Short stature 5 | 531
Waldenstrons macroglobulinemia 5 | 765
gastric cancer 5 | 459
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
pediatric high grade glioma 5 | 1,064
spina bifida 5 | 1,074
Bipolar Disorder 4 | 666
Curvature of spine 4 | 282
Depressive disorder 4 | 409
Down syndrome 4 | 499
Epilepsy 4 | 792
Strabismus 4 | 270
aldosterone-producing adenoma 4 | 665
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547
progressive supranuclear palsy 4 | 676

Tissue

Digestive Tract 58 | 17,369
Endocrine System 58 | 18,159
Female tissues 58 | 17,400
Nervous System 58 | 16,725
Skin and soft tissues 58 | 17,230
Blood and immune system 57 | 16,909
Liver and Pancreas 57 | 16,750
Respiratory system 57 | 16,393
Male tissues 56 | 17,142
Urinary Tract 56 | 16,678
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 8 | 4,145
Transcription Factor 6 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

negative regulation of cell de... 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like DUS2 Tbio Enzyme -0.88176 8.73 109
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Cytoplasmic protein NCK1 NCK1 Tbio Non-IDG -2.25032 186.5 398
Neuronal PAS domain-containing protein 2 NPAS2 Tbio Transcription Factor -1.91320 81.4 182
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.45155 278.6 88
WNT1-inducible-signaling pathway protein 2 WISP2 Tbio Non-IDG -1.73307 66.5 212
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 Tbio Enzyme -2.99264 1021.1 225
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058