Development Level

Tbio 2 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal tail morphology 1 | 25
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
no spontaneous movement 1 | 1

Disease

Cancer 2 | 2,499
Cleft Lip 2 | 141
Cleft Palate 2 | 271
Craniofacial Abnormalities 2 | 151
22q11 Deletion Syndrome 1 | 10
Abnormality of body height 1 | 13
Abnormality of the cranial nerves 1 | 7
Abnormality of the voice 1 | 46
Absence of pubertal development 1 | 17
Absence of secondary sex characteristics 1 | 22
Achondroplasia 1 | 21
Alobar Holoprosencephaly 1 | 14
Anosmia 1 | 22
Anterior hypopituitarism 1 | 18
Anteverted ears 1 | 2
Anxiety 1 | 136
Anxiety disease 1 | 113
Autosomal recessive nonsyndromic deafness 63 1 | 10
Breast Neoplasms 1 | 445
Broad flat nasal bridge 1 | 236
CHARGE syndrome 1 | 26
Carcinoma, Hepatocellular 1 | 228
Cardiovascular Abnormalities 1 | 31
Choanal Atresia 1 | 42
Congenital aplasia of inner ear 1 | 1
Congenital heart disease 1 | 93
Congenital hypoplasia of breast 1 | 25
Congenital small ears 1 | 48
Cranial nerve abnormality 1 | 7
Deafness with labyrinthine aplasia, microtia, and microdontia 1 | 1
Deafness, Congenital, with Inner Ear Agenesis, Microtia, and Microdontia 1 | 1
Decreased bone mineral density Z score 1 | 31
Decreased fertility 1 | 33
Decreased size of teeth 1 | 62
Decreased testosterone in males 1 | 28
Decreased width of tooth 1 | 59
Delayed Puberty 1 | 97
Delayed bone age 1 | 136
Depressive disorder 1 | 409
DiGeorge syndrome 1 | 47
Downward slant of palpebral fissure 1 | 158
Erectile abnormalities 1 | 16
Erectile dysfunction 1 | 32
Eunuchoid habitus 1 | 14
Female hypogonadism syndrome 1 | 25
Generalized osteopenia 1 | 99
Gross motor development delay 1 | 21
Gynecomastia 1 | 64
Hearing Loss, Sensorineural 1 | 11
Holoprosencephaly 1 | 56
Hypochondroplasia 1 | 10
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypospadias 1 | 53
Hypothalamic gonadotropin-releasing hormone deficiency 1 | 14
Increased female libido 1 | 13
Infantile uterus 1 | 23
Kallmann Syndrome 2 (disorder) 1 | 18
Kallmann syndrome 1 | 33
Klinefelter's syndrome 1 | 56
LADD syndrome 1 | 9
Liver carcinoma 1 | 240
Mammary Neoplasms 1 | 425
Microdontia (disorder) 1 | 59
Microtia, first degree 1 | 3
Nasal bridge wide 1 | 236
Non-obstructive azoospermia 1 | 21
Oculootodental Syndrome 1 | 2
Osteopenia 1 | 99
Osteoporosis 1 | 363
Otodental Dysplasia 1 | 2
Parkinson's disease 1 | 392
Peg-shaped teeth 1 | 8
Pointed chin 1 | 33
Pointed teeth 1 | 8
Primary physiologic amenorrhea 1 | 55
Profound sensorineural hearing impairment 1 | 4
Renal agenesis 1 | 29
Secondary physiologic amenorrhea 1 | 32
Semilobar Holoprosencephaly 1 | 14
Sense of smell impaired 1 | 21
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Skin tag 1 | 14
Small testicle 1 | 75
Sparse body hair 1 | 32
Stomatognathic Diseases 1 | 2
Synostosis 1 | 15
Testicular hypogonadism 1 | 21
Thanatophoric dysplasia 1 | 7
Thin hypoplastic alae nasi 1 | 51
Tooth agenesis 1 | 44
Type 1 diabetes mellitus 12 1 | 2
Type 1 diabetes mellitus 4 1 | 7
Type 1 diabetes mellitus 5 1 | 4
Type 1 diabetes mellitus 8 1 | 6
Velocardiofacial syndrome 1 | 46
Wide spaced nipples 1 | 46
Widely spaced teeth 1 | 31
type 1 diabetes mellitus 2 1 | 3

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Non-IDG 2 | 12,091

GO Process

negative regulation of cardiac... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 3 FGF3 Tbio Non-IDG -2.29270 192.7 118
Fibroblast growth factor 8 FGF8 Tbio Non-IDG -2.73368 532.0 299