Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal eating behavior 1 | 1
abnormal forced expiratory flo... 1 | 1
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased threshold for audito... 1 | 26
decreased tidal volume 1 | 1
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
Cancer 5 | 2,499
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
psoriasis 5 | 6,694
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Mammary Neoplasms 3 | 425
Osteoporosis 3 | 363
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
nasopharyngeal carcinoma 3 | 1,058
Ankylosing spondylitis 2 | 140
Ankylosis 2 | 28
Fractures, Bone 2 | 13
active Crohn's disease 2 | 922
atypical teratoid / rhabdoid tumor 2 | 5,112
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Alobar Holoprosencephaly 1 | 14
Aplasia/Hypoplasia of the middle phalanges of the toes 1 | 5
Big calvaria 1 | 147
Bone pain 1 | 42
Brachydactyly 1 | 156
Bunion 1 | 26
Celiac disease 1 | 116
Choreatic disease 1 | 52
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Decreased projection of maxilla 1 | 66
Deficiency of upper jaw bones 1 | 66
Diarrhea 1 | 253
Downward slant of palpebral fissure 1 | 158
Endocarditis 1 | 19
Frequent fractures 1 | 53
Hallux Valgus 1 | 26
Heart conduction disease 1 | 83
Hemochromatosis type 1 1 | 9
Hypoplasia of the maxilla 1 | 66
Hypoplastic feet 1 | 66
Hypotrophic malar bone 1 | 129
Hypotrophic maxilla 1 | 66
Increased fracture rate 1 | 53
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Juvenile osteoporosis 1 | 4
Lymphoid leukemia 1 | 160
Malar flattening 1 | 129
Maxillary retrognathia 1 | 66
Microstomia 1 | 78
Multiple synostoses syndrome 1 | 9
Myopia 1 | 176
Neuroacanthocytosis 1 | 6
Neurodegeneration with brain iron accumulation 3 1 | 8
Neutropenia 1 | 72
Opioid abuse 1 | 5
Osteoarthritis 1 | 184
Osteomyelitis 1 | 42
Osteonecrosis 1 | 27
Otosclerosis 1 | 15
Periodontal disease 1 | 40
Radiculopathy 1 | 14
Refractive error 1 | 50
Retrusion of upper jaw bones 1 | 66
Root resorption 1 | 22
Scoliosis 1 | 44
Semilobar Holoprosencephaly 1 | 14
Sickle Cell Anemia 1 | 53
Spinocerebellar ataxia type 17 1 | 7
Spondylosis 1 | 16
Stomach Neoplasms 1 | 300
Thalassemia 1 | 53
Type 1 diabetes mellitus 1 | 109
Uremia 1 | 19
Varying degree of multiple fractures 1 | 53
Wolff-Parkinson-White syndrome 1 | 19
atypical teratoid/rhabdoid tumor 1 | 357
chronic kidney disease 1 | 90
dentatorubral-pallidoluysian atrophy 1 | 21
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 4 | 12,091
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Process

negative regulation of cardiac... 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Frizzled-7 FZD7 Tbio GPCR -1.81873 66.4 345
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Transcription factor SOX-6 SOX6 Tbio Transcription Factor -2.07304 118.4 172
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Delta-like protein 1 DLL1 Tbio Non-IDG -3.09375 1190.2 344