Development Level

Tbio 115 | 10,625
Tchem 36 | 1,890
Tclin 8 | 602
Tdark 3 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
decreased body length 4 | 108
decreased body weight 4 | 174
decreased lean body mass 4 | 195
decreased bone mineral density 3 | 126
decreased total body fat amoun... 3 | 186
embryonic lethality prior to t... 3 | 187
preweaning lethality, incomple... 3 | 260
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
decreased bone mineral content 2 | 157
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased lumbar vertebrae num... 2 | 62
enlarged heart 2 | 111
increased mean corpuscular vol... 2 | 91
short tibia 2 | 82
thrombocytopenia 2 | 46
abnormal behavioral response t... 1 | 52
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal iris morphology 1 | 12
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
abnormal tooth morphology 1 | 24
absent seminal vesicle 1 | 2
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating sodium l... 1 | 18
decreased erythrocyte cell num... 1 | 43
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
female infertility 1 | 34
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased cellular hemoglobin ... 1 | 2
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
kinked tail 1 | 3
limb grasping 1 | 35
male infertility 1 | 62
prolonged QRS complex duration 1 | 2

Disease

ovarian cancer 105 | 8,484
psoriasis 82 | 6,685
osteosarcoma 71 | 7,933
glioblastoma 66 | 5,572
Cancer 64 | 2,346
lung cancer 58 | 4,466
medulloblastoma, large-cell 56 | 6,234
atypical teratoid / rhabdoid tumor 50 | 4,369
Breast cancer 48 | 3,094
malignant mesothelioma 43 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,988
pediatric high grade glioma 41 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,956
pilocytic astrocytoma 37 | 3,086
non-small cell lung cancer 36 | 2,798
interstitial cystitis 35 | 2,299
invasive ductal carcinoma 35 | 2,950
oligodendroglioma 35 | 2,849
ependymoma 34 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,289
primitive neuroectodermal tumor 31 | 3,031
subependymal giant cell astrocytoma 30 | 2,287
Multiple myeloma 29 | 1,327
astrocytoma 29 | 1,493
lung carcinoma 29 | 2,844
pancreatic cancer 29 | 2,300
ulcerative colitis 28 | 2,087
lung adenocarcinoma 27 | 2,713
group 3 medulloblastoma 26 | 2,254
group 4 medulloblastoma 26 | 1,875
diabetes mellitus 24 | 1,663
astrocytic glioma 23 | 2,241
breast carcinoma 23 | 1,614
pituitary cancer 23 | 1,972
Pick disease 22 | 1,893
cystic fibrosis 22 | 1,665
posterior fossa group A ependymoma 22 | 1,511
Carcinoma 21 | 2,147
dermatomyositis 19 | 933
acute quadriplegic myopathy 18 | 1,157
juvenile dermatomyositis 18 | 1,189
primary pancreatic ductal adenocarcinoma 18 | 1,271
cutaneous lupus erythematosus 17 | 1,056
ductal carcinoma in situ 17 | 1,745
non primary Sjogren syndrome sicca 17 | 840
sonic hedgehog group medulloblastoma 17 | 1,482
adrenocortical carcinoma 16 | 1,427
gastric carcinoma 16 | 832
HIV Infections 15 | 100
colon cancer 14 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
spina bifida 14 | 1,064
Duchenne muscular dystrophy 13 | 602
Osteoporosis 12 | 257
Waldenstrons macroglobulinemia 12 | 765
active Crohn's disease 12 | 918
acute myeloid leukemia 12 | 780
medulloblastoma 12 | 1,524
posterior fossa group B ependymoma 12 | 1,530
Alzheimer's disease 11 | 644
Atopic dermatitis 11 | 944
Obesity 11 | 616
Rheumatoid Arthritis 11 | 1,160
atypical teratoid/rhabdoid tumor 11 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
Colorectal Neoplasms 10 | 217
Mammary Neoplasms 10 | 410
esophageal adenocarcinoma 10 | 737
Down syndrome 9 | 548
Kidney disease 9 | 396
primary Sjogren syndrome 9 | 789
progressive supranuclear palsy 9 | 674
tuberculosis and treatment for 6 months 9 | 686
fibroadenoma 8 | 557
glioblastoma multiforme 8 | 347
tuberculosis 8 | 1,557
Amyotrophic Lateral Sclerosis 7 | 431
Colonic Neoplasms 7 | 126
Endometriosis 7 | 535
Lung Neoplasms 7 | 171
Parkinson's disease 7 | 364
Prostatic Neoplasms 7 | 471
Robinow syndrome 7 | 12
Vascular disease 7 | 281
adult high grade glioma 7 | 2,148
aldosterone-producing adenoma 7 | 664
nasopharyngeal carcinoma 7 | 1,056
nephrosclerosis 7 | 329
sarcoidosis 7 | 358
urothelial carcinoma 7 | 318
Myocardial Infarction 6 | 126
Osteoarthritis 6 | 96
Peripheral Neuropathy 6 | 303
Stomach Neoplasms 6 | 282
hepatocellular carcinoma 6 | 532
non-inflammatory breast cancer 6 | 208
Becker muscular dystrophy 5 | 187
Crohn's disease 5 | 304
Schizophrenia 5 | 501
inflammatory breast cancer 5 | 404

Tissue

Blood and immune system 162 | 17,995
Digestive Tract 162 | 18,473
Endocrine System 162 | 18,512
Female tissues 162 | 18,647
Liver and Pancreas 162 | 18,136
Male tissues 162 | 17,969
Nervous System 162 | 18,561
Urinary Tract 162 | 18,444
Cardiovascular System 161 | 17,958
Respiratory system 161 | 17,484
Skin and soft tissues 161 | 18,115

Target Family

Non-IDG 82 | 11,971
Enzyme 50 | 4,146
Transcription Factor 15 | 1,400
Kinase 10 | 634
Epigenetic 3 | 242
GPCR 2 | 406

GO Process

negative regulation of canonic... 162 | 162
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Protein Jade-1 JADE1 Tbio Epigenetic -0.97841 12.2 121
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha PPP2R3A Tbio Enzyme -1.19072 14.4 144
26S proteasome non-ATPase regulatory subunit 8 PSMD8 Tbio Enzyme -1.35900 20.6 94
Transcriptional activator GLI3 GLI3 Tbio Transcription Factor -3.17963 1388.1 188
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48