Development Level

Tbio 129 | 11,445
Tchem 22 | 1,598
Tclin 8 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 6 | 499
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
decreased body length 3 | 101
decreased lean body mass 3 | 135
embryonic lethality prior to t... 3 | 278
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased prepulse inhibition 2 | 82
female infertility 2 | 60
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
male infertility 2 | 123
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal embryo development 1 | 7
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased kidney weight 1 | 1
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
microphthalmia 1 | 26
polydactyly 1 | 7
premature death 1 | 5
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
short tibia 1 | 97
small heart 1 | 10
small spleen 1 | 19
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 109 | 8,520
Carcinoma 106 | 11,493
psoriasis 84 | 6,694
osteosarcoma 73 | 7,950
glioblastoma 70 | 5,792
lung cancer 67 | 4,740
Cancer 66 | 2,499
ependymoma 60 | 4,679
Breast cancer 59 | 3,578
medulloblastoma, large-cell 58 | 6,241
atypical teratoid / rhabdoid tumor 55 | 5,112
group 3 medulloblastoma 45 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
malignant mesothelioma 43 | 3,232
non-small cell lung cancer 42 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,955
Astrocytoma, Pilocytic 37 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
oligodendroglioma 36 | 2,850
interstitial cystitis 35 | 2,312
invasive ductal carcinoma 35 | 2,951
pancreatic cancer 35 | 2,398
adult high grade glioma 34 | 3,801
lung carcinoma 31 | 2,843
primitive neuroectodermal tumor 31 | 3,035
Kidney cancer 30 | 2,613
subependymal giant cell astrocytoma 30 | 2,287
Multiple myeloma 29 | 1,332
astrocytic glioma 29 | 2,597
lung adenocarcinoma 29 | 2,716
breast carcinoma 25 | 1,638
astrocytoma 24 | 1,146
diabetes mellitus 24 | 1,728
ulcerative colitis 24 | 1,819
Pick disease 23 | 1,894
cystic fibrosis 23 | 1,696
pituitary cancer 23 | 1,972
group 4 medulloblastoma 22 | 1,855
dermatomyositis 20 | 966
juvenile dermatomyositis 20 | 1,187
acute quadriplegic myopathy 19 | 1,158
adrenocortical carcinoma 19 | 1,428
Autosomal recessive predisposition 18 | 1,442
ductal carcinoma in situ 18 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
cutaneous lupus erythematosus 17 | 1,057
primary pancreatic ductal adenocarcinoma 17 | 1,109
colon cancer 16 | 1,478
gastric carcinoma 16 | 807
spina bifida 16 | 1,074
HIV Infections 15 | 102
Schizophrenia 15 | 1,160
non primary Sjogren syndrome sicca 15 | 891
Intellectual disability 14 | 1,016
Osteoporosis 14 | 363
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
pediatric high grade glioma 14 | 1,064
Alzheimer's disease 13 | 658
Cognitive delay 13 | 608
Duchenne muscular dystrophy 13 | 601
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Obesity 13 | 678
Rheumatoid arthritis 13 | 1,191
Short stature 13 | 531
Atopic dermatitis 12 | 952
Bipolar Disorder 12 | 666
Breast Neoplasms 12 | 445
Waldenstrons macroglobulinemia 12 | 765
active Crohn's disease 12 | 922
acute myeloid leukemia 12 | 783
Big calvaria 10 | 147
Colorectal Neoplasms 10 | 243
Down syndrome 10 | 499
Dull intelligence 10 | 645
Increased head circumference 10 | 147
Increased size of cranium 10 | 147
Increased size of skull 10 | 147
Low intelligence 10 | 645
Mammary Neoplasms 10 | 425
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Orbital separation excessive 10 | 244
Parkinson's disease 10 | 392
Poor school performance 10 | 645
esophageal adenocarcinoma 10 | 737
Amyotrophic lateral sclerosis 9 | 451
Cryptorchidism 9 | 296
Kidney disease 9 | 430
Liver Cirrhosis, Experimental 9 | 769
Lung Neoplasms 9 | 232
fibroadenoma 9 | 559
medulloblastoma 9 | 720
primary Sjogren syndrome 9 | 735
progressive supranuclear palsy 9 | 676
tuberculosis 9 | 2,010
Cleft Palate 8 | 271
Congenital hypoplasia of penis 8 | 176
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275

Tissue

Endocrine System 163 | 18,159
Female tissues 163 | 17,400
Male tissues 162 | 17,142
Nervous System 162 | 16,725
Blood and immune system 161 | 16,909
Digestive Tract 161 | 17,369
Skin and soft tissues 161 | 17,230
Urinary Tract 161 | 16,678
Liver and Pancreas 160 | 16,750
Respiratory system 157 | 16,393
Cardiovascular System 152 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 50 | 4,145
Transcription Factor 15 | 1,400
Kinase 10 | 634
Epigenetic 3 | 242
GPCR 1 | 408

GO Process

negative regulation of canonic... 164 | 164
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Succinate dehydrogenase assembly factor 2, mitochondrial SDHAF2 Tbio Enzyme -1.86465 69.5 34
Transmembrane protein 64 TMEM64 Tdark Non-IDG -0.22185 1.46 9
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93