Development Level

Tbio 10 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal tooth morphology 1 | 24
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979

Disease

Cancer 9 | 2,499
Carcinoma 9 | 11,493
osteosarcoma 9 | 7,950
diabetes mellitus 7 | 1,728
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Heart disease 6 | 306
Kidney disease 6 | 430
Liver Cirrhosis 6 | 181
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
medulloblastoma, large-cell 6 | 6,241
Hypertension 5 | 396
Hypertensive disease 5 | 292
Lung disease 5 | 142
Schizophrenia 5 | 1,160
Vascular disease 5 | 319
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Alzheimer's disease 4 | 658
Arthritis 4 | 290
Atherosclerosis 4 | 291
Breast cancer 4 | 3,578
Cerebrovascular disease 4 | 238
Inflammation 4 | 120
Myocardial Infarction 4 | 151
breast carcinoma 4 | 1,638
glioblastoma 4 | 5,792
nasopharyngeal carcinoma 4 | 1,058
Adenocarcinoma 3 | 122
Atopic dermatitis 3 | 952
Carcinoma, Hepatocellular 3 | 228
Coronary artery disease 3 | 268
Diabetic retinopathy 3 | 56
Down syndrome 3 | 499
Hyperglycemia 3 | 137
Liver carcinoma 3 | 240
Liver disease 3 | 237
Mood Disorders 3 | 184
Myocardial Ischemia 3 | 169
Nerve Degeneration 3 | 121
Parkinson's disease 3 | 392
Pulmonary Fibrosis 3 | 106
Reperfusion Injury 3 | 86
Seizures 3 | 596
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Abortion, Spontaneous 2 | 109
Acute kidney injury 2 | 70
Adenoma 2 | 167
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer Disease 2 | 83
Breast Neoplasms 2 | 445
Cerebrovascular accident 2 | 63
Chemical and Drug Induced Liver Injury 2 | 195
Cholecystitis 2 | 18
Colorectal Neoplasms 2 | 243
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Disease Progression 2 | 136
Epistaxis 2 | 43
Hepatomegaly 2 | 285
Inflammatory bowel disease 2 | 151
Kidney Diseases 2 | 114
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Multiple Sclerosis 2 | 540
Neoplasm Metastasis 2 | 168
Neurodegenerative disease 2 | 414
Osteoporosis 2 | 363
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Polycystic ovary syndrome 2 | 360
Proteinuria 2 | 144
Renal Insufficiency 2 | 90
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
Thrombocythemia, Essential 2 | 12
Toxic encephalopathy 2 | 141
active ulcerative colitis 2 | 764
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hearing impairment 2 | 199

Tissue

Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Digestive Tract 13 | 17,369
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Nervous System 12 | 16,725

Target Family

Non-IDG 10 | 12,091
Kinase 2 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

negative regulation of blood v... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Angiopoietin-4 ANGPT4 Tbio Non-IDG -1.23983 17.7 193
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Casein kinase II subunit beta CSNK2B Tbio Kinase -2.72925 527.4 422
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Serine/threonine-protein kinase receptor R3 ACVRL1 Tchem Kinase -2.98370 969.8 432
Type-2 angiotensin II receptor AGTR2 Tchem GPCR -3.30172 1972.1 147
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Angiopoietin-2 ANGPT2 Tbio Non-IDG -2.81963 734.5 455
Peroxisome proliferator-activated receptor gamma PPARG Tclin Nuclear Receptor -3.96393 9579.5 773