Development Level

Tbio 23 | 11,445
Tchem 9 | 1,598
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased lean body mass 2 | 135
increased circulating alkaline... 2 | 122
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
enlarged liver 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 24 | 11,493
ovarian cancer 23 | 8,520
medulloblastoma, large-cell 19 | 6,241
Cancer 16 | 2,499
osteosarcoma 16 | 7,950
glioblastoma 14 | 5,792
psoriasis 14 | 6,694
ependymoma 12 | 4,679
lung cancer 12 | 4,740
atypical teratoid / rhabdoid tumor 11 | 5,112
diabetes mellitus 9 | 1,728
group 4 medulloblastoma 8 | 1,855
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
breast carcinoma 7 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
Schizophrenia 6 | 1,160
Seizures 6 | 596
astrocytic glioma 6 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Astrocytoma, Pilocytic 5 | 3,081
Breast Neoplasms 5 | 445
Epilepsy 5 | 792
Hypertension 5 | 396
Hypertensive disease 5 | 292
Mammary Neoplasms 5 | 425
Multiple myeloma 5 | 1,332
Obesity 5 | 678
Parkinson's disease 5 | 392
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Autistic Disorder 4 | 364
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Hepatocellular 4 | 228
Colorectal Neoplasms 4 | 243
Depressive disorder 4 | 409
Diabetes Mellitus, Experimental 4 | 108
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Gynecomastia 4 | 64
Hyperglycemia 4 | 137
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Liver Neoplasms, Experimental 4 | 59
Liver carcinoma 4 | 240
Liver disease 4 | 237
Lung Neoplasms 4 | 232
Myocardial Infarction 4 | 151
Neurodegenerative disease 4 | 414
Polycystic ovary syndrome 4 | 360
Vascular disease 4 | 319
Weight decreased 4 | 103
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
ulcerative colitis 4 | 1,819
Adenoma 3 | 167
Anemia 3 | 365
Arthritis 3 | 290
Asthma 3 | 385
Bipolar Disorder 3 | 666
Chronic Lymphocytic Leukemia 3 | 262
Endometrial cancer 3 | 311
Heart disease 3 | 306
Hyperinsulinism 3 | 133
Large intestine cancer 3 | 126
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Major Depressive Disorder 3 | 301
Mesothelioma, Malignant 3 | 105
Neoplasm Invasiveness 3 | 161
Osteoporosis 3 | 363
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Squamous cell carcinoma 3 | 129
Stomach Neoplasms 3 | 300
Toxic encephalopathy 3 | 141
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
fibroadenoma 3 | 559
medulloblastoma 3 | 720
primary Sjogren syndrome 3 | 735

Tissue

Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Respiratory system 37 | 16,393
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678

Target Family

Non-IDG 20 | 12,091
Enzyme 8 | 4,145
Kinase 4 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408

GO Process

negative regulation of autopha... 37 | 37
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Zinc finger protein with KRAB and SCAN domains 3 ZKSCAN3 Tbio Transcription Factor -0.90118 10.2 101
Kinesin-like protein KIF25 KIF25 Tbio Non-IDG -0.75019 5.59 191
Lysine-specific demethylase 4A KDM4A Tchem Epigenetic -3.06159 1089.8 271
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Death-associated protein-like 1 DAPL1 Tbio Non-IDG -0.91439 8.29 84
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein RUBCN Tbio Non-IDG -1.97676 93.5 93
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Metallothionein-3 MT3 Tbio Non-IDG -2.30937 197.7 87
Ras-interacting protein 1 RASIP1 Tbio Non-IDG -1.32949 18.7 77