Development Level

Tbio 7 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal behavior 1 | 298
abnormal femur morphology 1 | 14
abnormal rib morphology 1 | 10
abnormal vertebrae morphology 1 | 18
decreased prepulse inhibition 1 | 82
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
preweaning lethality, complete... 1 | 979
small spleen 1 | 19

Disease

Carcinoma 14 | 11,493
Cancer 13 | 2,499
glioblastoma 12 | 5,792
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
lung cancer 10 | 4,740
Breast cancer 9 | 3,578
osteosarcoma 9 | 7,950
ependymoma 8 | 4,679
invasive ductal carcinoma 8 | 2,951
atypical teratoid / rhabdoid tumor 7 | 5,112
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
Astrocytoma, Pilocytic 6 | 3,081
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
Carcinoma, Squamous Cell 5 | 110
Down syndrome 5 | 499
Kidney cancer 5 | 2,613
Neoplasm Invasiveness 5 | 161
Schizophrenia 5 | 1,160
Stomach Neoplasms 5 | 300
group 4 medulloblastoma 5 | 1,855
lung adenocarcinoma 5 | 2,716
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Adenoma 4 | 167
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Hepatocellular 4 | 228
Depressive disorder 4 | 409
Diabetes Mellitus, Experimental 4 | 108
Heart disease 4 | 306
Neoplasm Metastasis 4 | 168
Prostatic Neoplasms 4 | 495
Squamous cell carcinoma 4 | 129
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
group 3 medulloblastoma 4 | 4,104
juvenile dermatomyositis 4 | 1,187
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Arthritis 3 | 290
COPD 3 | 118
Cell Transformation, Neoplastic 3 | 97
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Hypertension 3 | 396
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Mental Depression 3 | 333
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple myeloma 3 | 1,332
Neoplastic Cell Transformation 3 | 89
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Poor school performance 3 | 645
Sarcoma 3 | 62
Splenomegaly 3 | 190
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
urothelial carcinoma 3 | 318
Atopic dermatitis 2 | 952
Cerebrovascular disease 2 | 238
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Polycystic ovary syndrome 2 | 360
pancreatic carcinoma 2 | 562

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 9 | 12,091
Kinase 5 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145

GO Process

negative regulation of anoikis 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 304 ZNF304 Tbio Transcription Factor -0.83471 4.32 16
Peptidyl-tRNA hydrolase 2, mitochondrial PTRH2 Tbio Enzyme -1.56520 39.8 293
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Integrin alpha-5 ITGA5 Tbio Non-IDG -2.29130 169.1 826
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
Carcinoembryonic antigen-related cell adhesion molecule 5 CEACAM5 Tbio Non-IDG -3.99745 9224.5 1614
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Integrin beta-1 ITGB1 Tclin Non-IDG -3.15400 1269.8 1956
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA Tclin Kinase -3.04988 1076.8 484