Development Level

Tbio 49 | 11,445
Tchem 12 | 1,598
Tclin 8 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal pericardium morpholog... 2 | 26
decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal allantois morphology 1 | 8
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal head morphology 1 | 10
abnormal heart looping 1 | 5
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal kidney morphology 1 | 65
abnormal left-right axis patte... 1 | 2
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail bud morphology 1 | 8
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
cataract 1 | 92
decreased body length 1 | 101
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased urine microalbumin l... 1 | 2
male infertility 1 | 123
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
prolonged ST segment 1 | 36
small seminal vesicle 1 | 10

Disease

Carcinoma 52 | 11,493
psoriasis 40 | 6,694
osteosarcoma 35 | 7,950
Cancer 34 | 2,499
lung cancer 34 | 4,740
medulloblastoma, large-cell 33 | 6,241
ovarian cancer 33 | 8,520
glioblastoma 30 | 5,792
Breast cancer 27 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
lung adenocarcinoma 26 | 2,716
ependymoma 25 | 4,679
invasive ductal carcinoma 25 | 2,951
atypical teratoid / rhabdoid tumor 24 | 5,112
interstitial cystitis 24 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
lung carcinoma 23 | 2,843
pancreatic cancer 23 | 2,398
adult high grade glioma 22 | 3,801
malignant mesothelioma 21 | 3,232
non-small cell lung cancer 21 | 2,890
breast carcinoma 18 | 1,638
cystic fibrosis 18 | 1,696
ulcerative colitis 18 | 1,819
Kidney cancer 17 | 2,613
ductal carcinoma in situ 17 | 1,745
Astrocytoma, Pilocytic 16 | 3,081
tuberculosis 16 | 2,010
diabetes mellitus 15 | 1,728
group 3 medulloblastoma 15 | 4,104
pituitary cancer 15 | 1,972
adrenocortical carcinoma 14 | 1,428
cutaneous lupus erythematosus 14 | 1,057
Kidney disease 13 | 430
nasopharyngeal carcinoma 13 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
oligodendroglioma 12 | 2,850
Hypertension 11 | 396
Obesity 11 | 678
gastric carcinoma 11 | 807
primitive neuroectodermal tumor 11 | 3,035
Atherosclerosis 10 | 291
Autosomal recessive predisposition 10 | 1,442
Coronary artery disease 10 | 268
astrocytic glioma 10 | 2,597
juvenile dermatomyositis 10 | 1,187
Arthritis 9 | 290
Atopic dermatitis 9 | 952
Dull intelligence 9 | 645
Heart disease 9 | 306
Hypersensitivity reaction type II disease 9 | 253
Inflammatory bowel disease 9 | 151
Intellectual disability 9 | 1,016
Low intelligence 9 | 645
Lung disease 9 | 142
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Multiple Sclerosis 9 | 540
Poor school performance 9 | 645
Vascular disease 9 | 319
esophageal adenocarcinoma 9 | 737
Asthma 8 | 385
Cerebrovascular disease 8 | 238
Hypertensive disease 8 | 292
Melanoma 8 | 711
Polycystic ovary syndrome 8 | 360
Prostatic Neoplasms 8 | 495
Schizophrenia 8 | 1,160
colon cancer 8 | 1,478
head and neck cancer 8 | 271
hepatocellular carcinoma 8 | 547
primary pancreatic ductal adenocarcinoma 8 | 1,109
Liver Cirrhosis 7 | 181
Liver cancer 7 | 604
Seizures 7 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
dermatomyositis 7 | 966
medulloblastoma 7 | 720
subependymal giant cell astrocytoma 7 | 2,287
Alzheimer's disease 6 | 658
Duchenne muscular dystrophy 6 | 601
Eye disease 6 | 62
Heart failure 6 | 162
Liver Cirrhosis, Experimental 6 | 769
Malaria 6 | 160
Multiple myeloma 6 | 1,332
Myocardial Ischemia 6 | 169
Pick disease 6 | 1,894
Skin cancer 6 | 469
active ulcerative colitis 6 | 764
fibroadenoma 6 | 559
spina bifida 6 | 1,074
Endometriosis 5 | 540
Epilepsy 5 | 792
Glaucoma 5 | 239
Strabismus 5 | 270
astrocytoma 5 | 1,146
mucosa-associated lymphoid tissue lymphoma 5 | 484
pediatric high grade glioma 5 | 1,064

Tissue

Endocrine System 69 | 18,159
Digestive Tract 68 | 17,369
Female tissues 68 | 17,400
Liver and Pancreas 67 | 16,750
Urinary Tract 67 | 16,678
Blood and immune system 66 | 16,909
Male tissues 66 | 17,142
Skin and soft tissues 66 | 17,230
Respiratory system 65 | 16,393
Nervous System 63 | 16,725
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 41 | 12,091
Enzyme 7 | 4,145
GPCR 7 | 408
Kinase 7 | 634
Transcription Factor 6 | 1,400
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

negative regulation of angioge... 70 | 70
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stabilin-1 STAB1 Tbio Non-IDG -1.61013 45.4 107
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Extracellular sulfatase Sulf-1 SULF1 Tbio Enzyme -1.90276 92.2 61
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Ephrin-A3 EFNA3 Tbio Non-IDG -1.53049 26.8 219
Receptor-type tyrosine-protein phosphatase mu PTPRM Tchem Enzyme -1.84748 71.7 144
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
G-protein coupled receptor 4 GPR4 Tchem GPCR -1.62311 46.9 119
Phosphoglycerate kinase 1 PGK1 Tchem Kinase -2.79738 602.5 340