Development Level

Tchem 16 | 1,598
Tclin 8 | 613
Tbio 5 | 11,445
Tdark 5 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal gait 1 | 69
abnormal head morphology 1 | 10
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating triglyce... 1 | 42
increased mean platelet volume 1 | 45
limb grasping 1 | 41
microphthalmia 1 | 26
premature death 1 | 5
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38

Disease

Carcinoma 25 | 11,493
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
group 3 medulloblastoma 14 | 4,104
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 13 | 7,950
Alcoholic Intoxication, Chronic 12 | 289
Schizophrenia 12 | 1,160
ependymoma 11 | 4,679
lung cancer 11 | 4,740
ovarian cancer 11 | 8,520
Astrocytoma, Pilocytic 10 | 3,081
adult high grade glioma 10 | 3,801
lung carcinoma 10 | 2,843
Breast cancer 9 | 3,578
Kidney cancer 9 | 2,613
primitive neuroectodermal tumor 9 | 3,035
Depressive disorder 8 | 409
Mental Depression 8 | 333
oligodendroglioma 8 | 2,850
Alcohol abuse 7 | 50
Major Depressive Disorder 7 | 301
invasive ductal carcinoma 7 | 2,951
lung adenocarcinoma 7 | 2,716
Attention deficit hyperactivity disorder 6 | 278
Bipolar Disorder 6 | 666
Epilepsy 6 | 792
Mood Disorders 6 | 184
Parkinson's disease 6 | 392
Unipolar Depression 6 | 250
astrocytoma 6 | 1,146
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Alcohol dependence 5 | 107
Amphetamine-Related Disorders 5 | 74
Autistic Disorder 5 | 364
Cancer 5 | 2,499
Cocaine Dependence 5 | 51
Hypertension 5 | 396
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Asthma 4 | 385
Cocaine-Related Disorders 4 | 92
Gilles de la Tourette syndrome 4 | 47
Melanoma 4 | 711
Narcolepsy 4 | 72
Nicotine dependence 4 | 54
Opiate dependence 4 | 29
Pick disease 4 | 1,894
Seizures 4 | 596
Substance abuse 4 | 59
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
Allergic rhinitis 3 | 94
Alzheimer's disease 3 | 658
Amnesia 3 | 17
Attention Deficit Disorder with Hyperactivity 3 | 21
Chronic schizophrenia 3 | 16
Cognition Disorders 3 | 32
Depressive Disorder, Major 3 | 19
Heroin dependence 3 | 30
Hyperactive behavior 3 | 91
Hyperkinesis 3 | 32
Hypertensive disease 3 | 292
Memory Disorders 3 | 40
Movement Disorders 3 | 55
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Muscle Spasticity of Cerebral Origin 3 | 8
Muscle spasticity of spinal origin 3 | 8
Nasal congestion 3 | 21
Nasal discharge 3 | 24
Nausea and vomiting 3 | 97
Obesity 3 | 678
Pathological gambling 3 | 15
Schizoaffective Disorder 3 | 55
Skin cancer 3 | 469
Substance-Related Disorders 3 | 115
Toxic encephalopathy 3 | 141
Waldenstrons macroglobulinemia 3 | 765
Weight Gain 3 | 100
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
fibroadenoma 3 | 559
head and neck cancer 3 | 271
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
mucosa-associated lymphoid tissue lymphoma 3 | 484
Psychotic Disorders 2 | 151

Tissue

Endocrine System 30 | 18,159
Skin and soft tissues 28 | 17,230
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Blood and immune system 25 | 16,909
Respiratory system 24 | 16,393
Urinary Tract 24 | 16,678
Liver and Pancreas 23 | 16,750
Cardiovascular System 18 | 15,192

Target Family

GPCR 21 | 408
Non-IDG 6 | 12,091
oGPCR 5 | 421
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

negative regulation of adenyla... 34 | 34
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Histamine H3 receptor HRH3 Tclin GPCR -2.76107 570.2 318
Paralemmin-1 PALM Tbio Non-IDG -1.24016 17.2 62
Alpha-2A adrenergic receptor ADRA2A Tclin GPCR -2.42160 261.4 232
Gamma-aminobutyric acid type B receptor subunit 2 GABBR2 Tclin GPCR -1.97367 92.4 395
Leukotriene B4 receptor 2 LTB4R2 Tchem GPCR -1.84108 77.0 161
D(4) dopamine receptor DRD4 Tchem GPCR -2.87568 745.0 367
Olfactory receptor 13F1 OR13F1 Tdark oGPCR 0.00000 69
Olfactory receptor 56A4 OR56A4 Tdark oGPCR 0.00000 8