Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged testis 1 | 6
increased body weight 1 | 25
increased circulating triglyce... 1 | 42
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
Cancer 4 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
Acquired scoliosis 2 | 281
Atopic dermatitis 2 | 952
Bilateral fifth finger clinodactyly 2 | 110
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Chromosome 1p36 deletion syndrome 2 | 23
Cognitive delay 2 | 608
Conductive hearing loss 2 | 123
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Isolated cases 2 | 72
Mammary Neoplasms 2 | 425
Mental and motor retardation 2 | 608
Metaphyseal widening 2 | 22
Multiple, subcutaneous nodules 2 | 53
Myopia 2 | 176
Orbital separation excessive 2 | 244
Pediatric failure to thrive 2 | 365
Small head 2 | 374
Subcutaneous nodule 2 | 53
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
non-small cell lung cancer 2 | 2,890
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormal cortical bone morphology 1 | 22
Abnormal vertebral bodies 1 | 16
Accessory rib 1 | 10
Acquired flat foot 1 | 72
Acute Lung Injury 1 | 22
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Ankylosis 1 | 28
Anxiety Disorders 1 | 38
Aortic aneurysm 1 | 38
Arnold-Chiari Malformation, Type I 1 | 5
Auricular malformation 1 | 41
Broad femoral neck 1 | 4
Bunion 1 | 26
Cataract 8 multiple types 1 | 33
Congenital anomaly of spine 1 | 16
Congenital musculoskeletal anomalies 1 | 5
Congenital pectus carinatum 1 | 52
Craniometaphyseal dysplasia 1 | 5
Decreased projection of midface 1 | 105
Deglutition Disorders 1 | 132
Dilatation of aorta 1 | 9
Ectopic pregnancy 1 | 16
Epidermodysplasia verruciformis 1 | 21
Flatfoot 1 | 73
Generalized hypopigmentation 1 | 12
Genu recurvatum 1 | 12
Gestational diabetes 1 | 26
Glioma 1 | 74
Glomangiomatosis 1 | 4
Hallux Valgus 1 | 26
High-grade hypermetropia 1 | 24
Hoarseness 1 | 31
Hooked clavicle 1 | 5
Hyperostosis 1 | 18
Hypotrophic midface 1 | 105
Joint laxity 1 | 54
Malocclusion 1 | 57
Memory Disorders 1 | 40
Metatarsus Varus 1 | 24
Midface retrusion 1 | 105
Mild Mental Retardation 1 | 70
Minimal subcutaneous fat 1 | 2
Mitral Valve Prolapse Syndrome 1 | 39
Multiple vertebral anomalies 1 | 16
Musculoskeletal Abnormalities 1 | 6
Narrow palate 1 | 20
Opisthorchiasis 1 | 15
Osteosclerosis 1 | 31
Papule 1 | 43
Poor speech 1 | 37
Problems speaking 1 | 37
Pseudoxanthoma elasticum 1 | 18
Self-Injurious Behavior 1 | 12
Shallow orbits 1 | 13
Sideroblastic anemia with spinocerebellar ataxia 1 | 6
Simple ear 1 | 41
Sleep Apnea, Obstructive 1 | 10
Small midface 1 | 105
Toeing-in 1 | 24
Widely spaced teeth 1 | 31

Tissue

Digestive Tract 7 | 17,369
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Endocrine System 6 | 18,159
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 5 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

negative regulation of activin... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
Inner nuclear membrane protein Man1 LEMD3 Tbio Non-IDG -2.30311 196.6 73
Follistatin-related protein 3 FSTL3 Tbio Non-IDG -1.80964 76.6 138
Follistatin FST Tbio Non-IDG -3.07812 1179.4 356
Cerberus CER1 Tbio Non-IDG -2.32331 194.4 188
Ski oncogene SKI Tbio Non-IDG -1.78249 59.9 124
Activin receptor type-1 ACVR1 Tchem Kinase -2.47071 290.9 428