Development Level

Tbio 35 | 10,625
Tchem 7 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

abnormal embryo size 3 | 112
embryonic lethality prior to t... 3 | 187
enlarged heart 3 | 111
preweaning lethality, complete... 3 | 633
abnormal bone mineralization 2 | 55
cleft palate 2 | 6
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased lean body mass 2 | 195
increased startle reflex 2 | 38
abnormal behavior 1 | 226
abnormal body wall morphology 1 | 7
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal eyelid morphology 1 | 6
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal head size 1 | 1
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal limb bud morphology 1 | 15
abnormal motor learning 1 | 4
abnormal pericardium morpholog... 1 | 11
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
craniofacial phenotype 1 | 9
decreased alpha-beta T cell nu... 1 | 12
decreased bone mineral content 1 | 157
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
facial cleft 1 | 3
immune system phenotype 1 | 17
improved glucose tolerance 1 | 56
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased rib number 1 | 41
kinked tail 1 | 3
mydriasis 1 | 9
pallor 1 | 13
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small adrenal glands 1 | 15
thrombocytosis 1 | 23

Disease

psoriasis 25 | 6,685
ovarian cancer 21 | 8,491
osteosarcoma 18 | 7,933
Cancer 16 | 2,346
atypical teratoid / rhabdoid tumor 15 | 4,369
glioblastoma 15 | 5,572
lung cancer 14 | 4,473
medulloblastoma, large-cell 13 | 6,234
oligodendroglioma 13 | 2,849
pilocytic astrocytoma 13 | 3,086
Breast cancer 12 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
invasive ductal carcinoma 11 | 2,950
astrocytoma 10 | 1,493
interstitial cystitis 10 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
pancreatic cancer 10 | 2,300
sonic hedgehog group medulloblastoma 10 | 1,482
cystic fibrosis 9 | 1,670
lung carcinoma 9 | 2,844
pediatric high grade glioma 9 | 2,712
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,271
primitive neuroectodermal tumor 9 | 3,031
subependymal giant cell astrocytoma 9 | 2,287
Colorectal Neoplasms 8 | 217
Mammary Neoplasms 8 | 410
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
Carcinoma 7 | 2,147
astrocytic glioma 7 | 2,241
ductal carcinoma in situ 7 | 1,745
ependymoma 7 | 2,514
posterior fossa group B ependymoma 7 | 1,530
ulcerative colitis 7 | 2,087
breast carcinoma 6 | 1,614
colon cancer 6 | 1,475
diabetes mellitus 6 | 1,663
lung adenocarcinoma 6 | 2,714
malignant mesothelioma 6 | 3,163
non-small cell lung cancer 6 | 2,798
cutaneous lupus erythematosus 5 | 1,056
medulloblastoma 5 | 1,524
posterior fossa group A ependymoma 5 | 1,511
Intellectual disability 4 | 573
Osteoporosis 4 | 259
Squamous cell carcinoma 4 | 96
Stomach Neoplasms 4 | 282
adult high grade glioma 4 | 2,148
group 4 medulloblastoma 4 | 1,875
Acquired metabolic disease 3 | 267
Adenoma 3 | 165
Chronic obstructive pulmonary disease 3 | 147
Duchenne muscular dystrophy 3 | 602
Epilepsy 3 | 346
Esophageal Neoplasms 3 | 67
Multiple myeloma 3 | 1,327
Obesity 3 | 616
Pick disease 3 | 1,893
Schizophrenia 3 | 503
active Crohn's disease 3 | 918
adrenocortical carcinoma 3 | 1,427
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic lymphocytic leukemia 3 | 244
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 557
gastric carcinoma 3 | 832
hepatocellular carcinoma 3 | 550
non diabetic and post-ischemic heart failure 3 | 200
spina bifida 3 | 1,064
tuberculosis 3 | 1,563
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 432
Arthritis 2 | 248
Atopic dermatitis 2 | 944
Autistic Disorder 2 | 320
Blood pressure finding 2 | 56
Down syndrome 2 | 548
Endometriosis 2 | 535
Inflammatory Bowel Diseases 2 | 87
Liver carcinoma 2 | 217
Lung Neoplasms 2 | 171
Migraine 2 | 79
Parkinson's disease 2 | 364
Prostatic Neoplasms 2 | 471
Waldenstrons macroglobulinemia 2 | 764
active ulcerative colitis 2 | 477
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic rhinosinusitis 2 | 512
facioscapulohumeral dystrophy 2 | 286
head and neck cancer 2 | 270
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
limb girdle muscular dystrophy 2A 2 | 156
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
periodontitis 2 | 269
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686
type II diabetes mellitus and post-ischemic heart failure 2 | 89
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 44 | 17,994
Cardiovascular System 44 | 17,957
Digestive Tract 44 | 18,472
Endocrine System 44 | 18,511
Female tissues 44 | 18,646
Liver and Pancreas 44 | 18,135
Male tissues 44 | 17,968
Nervous System 44 | 18,560
Respiratory system 44 | 17,483
Skin and soft tissues 44 | 18,114
Urinary Tract 44 | 18,443

Target Family

Non-IDG 28 | 11,969
Transcription Factor 7 | 1,400
Enzyme 6 | 4,146
Kinase 2 | 634
Epigenetic 1 | 242

GO Process

negative regulation of Wnt sig... 44 | 44
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.56179 2916.0 232
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.74198 552.4 624
Dapper homolog 1 DACT1 Tbio Non-IDG -1.84982 75.1 93
Protein shisa-2 homolog SHISA2 Tdark Non-IDG -0.56820 3.53 41
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.83160 648.7 196
Homeobox protein goosecoid GSC Tbio Transcription Factor -0.74905 6.29 290
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.48331 327.1 537
Dapper homolog 3 DACT3 Tbio Non-IDG -1.71906 50.6 126
CXXC-type zinc finger protein 4 CXXC4 Tbio Non-IDG -0.91005 8.05 0
Palmitoleoyl-protein carboxylesterase NOTUM NOTUM Tchem Enzyme -2.20949 149.5 98