Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
osteosarcoma 7 | 7,950
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
medulloblastoma, large-cell 5 | 6,241
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Epilepsy 3 | 792
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
tuberculosis 3 | 2,010
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Squamous Cell 2 | 110
Cognitive delay 2 | 608
Downward slant of palpebral fissure 2 | 158
Endometrial cancer 2 | 311
Global developmental delay 2 | 608
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Squamous cell carcinoma 2 | 129
acute quadriplegic myopathy 2 | 1,158
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
Absence Epilepsy 1 | 22
Adenocarcinoma 1 | 122
Adenocarcinoma of lung (disorder) 1 | 60
Anorexia 1 | 43
Ataxia telangiectasia 1 | 34
B-Cell Lymphomas 1 | 12
BILIARY TRACT ABNORMALITY 1 | 16
Biliary Tract Diseases 1 | 16
Birthmark 1 | 35
Bowed and upward slanting eyebrows 1 | 41
Bronchiectasis 1 | 64
CMM1 1 | 5
Cafe-au-Lait Spots 1 | 37
Carcinoma of pancreas 1 | 5
Carcinoma, Pancreatic Ductal 1 | 20
Cervix carcinoma 1 | 10
Chromosome Breakage 1 | 36
DOID:9917 1 | 31
Delayed Puberty 1 | 97
EPILEPSY, LATERAL TEMPORAL LOBE, AUTOSOMAL DOMINANT 1 | 3
Epilepsy, Familial Temporal Lobe, 1 1 | 3
Epileptic encephalopathy 1 | 26
Female hypogonadism syndrome 1 | 25
Fibrosis 1 | 44
Gonadal Dysgenesis 1 | 28
Gonadal Dysgenesis, Mixed 1 | 19
Gynecomastia 1 | 64
Hair shaft abnormalities 1 | 30
Hamman-Rich syndrome 1 | 34
Hyperpigmented macules 1 | 42
Immunoglobulin A deficiency (disorder) 1 | 19
Impaired glucose tolerance 1 | 28
Increased chromosomal breakage 1 | 27
Increased risk of pancreatic cancer 1 | 9
Lymphoma, T-Cell, Cutaneous 1 | 22
Lymphoma, T-Cell, Peripheral 1 | 9
Malignant neoplasm of pancreas 1 | 9
Myoclonus 1 | 74
Neoplasms 1 | 63
Nijmegen breakage syndrome 1 | 24
Ovarian Cysts 1 | 41
Peutz-Jeghers syndrome 1 | 21
Premature canities 1 | 24
Pure gonadal dysgenesis 1 | 19
Rectal prolapse 1 | 19
Recurrent bronchitis 1 | 23
Sclerocystic Ovaries 1 | 17
Sinusitis 1 | 65
Testicular Germ Cell Tumor 1 | 14
Thick, flared eyebrows 1 | 41
Ventricular Dysfunction, Left 1 | 22
Werner syndrome 1 | 29
Xeroderma pigmentosum 1 | 43
hair abnormalities (non-specific) 1 | 30

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 11 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

GO Process

negative regulation of TORC1 s... 14 | 14
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sestrin-1 SESN1 Tbio Non-IDG -1.95681 82.0 172
KICSTOR complex protein SZT2 SZT2 Tbio Non-IDG -0.87849 6.65 52
Small regulatory polypeptide of amino acid response SPAAR Tbio Non-IDG 0.00000 0
Sestrin-2 SESN2 Tbio Non-IDG -1.88129 92.6 176
Cytosolic arginine sensor for mTORC1 subunit 2 CASTOR2 Tbio Non-IDG 0.00000 18
E3 ubiquitin-protein ligase RNF152 RNF152 Tbio Enzyme -0.34321 1.96 2
KICSTOR complex protein C12orf66 C12orf66 Tbio Non-IDG 0.65 0.20 7
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
Cytosolic arginine sensor for mTORC1 subunit 1 CASTOR1 Tbio Non-IDG 0.00000 14
GATOR complex protein DEPDC5 DEPDC5 Tbio Non-IDG -1.59072 33.7 50