Development Level

Tbio 7 | 10,625
Tchem 2 | 1,890

IMPC Phenotype

impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased mean corpuscular vol... 1 | 91
preweaning lethality, complete... 1 | 633

Disease

Breast cancer 4 | 3,098
medulloblastoma, large-cell 4 | 6,234
osteosarcoma 4 | 7,933
ovarian cancer 4 | 8,491
Carcinoma 3 | 2,147
non primary Sjogren syndrome sicca 3 | 840
non-small cell lung cancer 3 | 2,798
Cancer 2 | 2,346
Liver carcinoma 2 | 217
Neoplastic Syndromes, Hereditary 2 | 48
Pancreatic Neoplasm 2 | 79
Pick disease 2 | 1,893
Prostatic Neoplasms 2 | 471
acute quadriplegic myopathy 2 | 1,157
astrocytic glioma 2 | 2,241
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
glioblastoma 2 | 5,572
lung cancer 2 | 4,473
malignant mesothelioma 2 | 3,163
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
psoriasis 2 | 6,685
Adenocarcinoma 1 | 115
Adenocarcinoma of lung (disorder) 1 | 48
Adenoid Cystic Carcinoma 1 | 99
Amyotrophic Lateral Sclerosis 1 | 432
Ataxia telangiectasia 1 | 32
Attention deficit hyperactivity disorder 1 | 156
Bannayan-Riley-Ruvalcaba syndrome 1 | 8
Bladder Neoplasm 1 | 109
Bloom syndrome 1 | 30
Breast Cancer, Familial 1 | 12
CMM1 1 | 5
Carcinoma of pancreas 1 | 5
Cardiomyopathy, Dilated 1 | 47
Cataract 1 | 104
Cerebellar Ataxia 1 | 72
Cowden disease 1 | 20
Duchenne muscular dystrophy 1 | 602
Epilepsy 1 | 346
Epilepsy, familial temporal lobe, 1 1 | 3
Fanconi's anemia 1 | 50
Fibrosis 1 | 40
Hamman-Rich syndrome 1 | 35
Hepatitis C 1 | 90
Hypertensive disease 1 | 193
Immune system cancer 1 | 38
Intussusception 1 | 5
Juvenile polyposis syndrome 1 | 7
Kidney cancer 1 | 121
Left Ventricular Hypertrophy 1 | 24
Lung Neoplasms 1 | 171
Lymphoid leukemia 1 | 69
Lymphoma, T-Cell, Cutaneous 1 | 21
MELANOMA, CUTANEOUS MALIGNANT, 1 1 | 4
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 1 | 12
Malignant neoplasm of testis 1 | 5
Mammary Neoplasms 1 | 410
Mantle cell lymphoma 1 | 20
Melanoma 1 | 261
Microcephaly 1 | 149
Multiple Sclerosis 1 | 498
Myocardial Infarction 1 | 126
Neurodegenerative disease 1 | 383
Nijmegen breakage syndrome 1 | 23
Peripheral Neuropathy 1 | 303
Peripheral T-cell lymphoma 1 | 24
Peutz-Jeghers syndrome 1 | 23
Prenatal Exposure Delayed Effects 1 | 9
Primary cutaneous T-cell lymphoma 1 | 29
Pulmonary emphysema 1 | 34
Seckel syndrome 1 | 35
Squamous cell carcinoma 1 | 96
Stomach Neoplasms 1 | 282
Telangiectasis 1 | 20
Testicular germ cell tumor 1 | 23
Ventricular Dysfunction, Left 1 | 15
Waldenstrons macroglobulinemia 1 | 764
Werner syndrome 1 | 29
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
chronic lymphocytic leukemia 1 | 244
colon cancer 1 | 1,475
hepatocellular carcinoma 1 | 550
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,289
juvenile dermatomyositis 1 | 1,189
limb girdle muscular dystrophy 2A 1 | 156
lung adenocarcinoma 1 | 2,714
medulloblastoma 1 | 1,524
pancreatic carcinoma 1 | 567
primary pancreatic ductal adenocarcinoma 1 | 1,271
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327
type II diabetes mellitus and post-ischemic heart failure 1 | 89

Tissue

Blood and immune system 9 | 17,994
Cardiovascular System 9 | 17,957
Digestive Tract 9 | 18,472
Female tissues 9 | 18,646
Liver and Pancreas 9 | 18,135
Male tissues 9 | 17,968
Nervous System 9 | 18,560
Endocrine System 8 | 18,511
Respiratory system 8 | 17,483
Skin and soft tissues 8 | 18,114
Urinary Tract 8 | 18,443

Target Family

Non-IDG 6 | 11,969
Kinase 2 | 634
Enzyme 1 | 4,146

GO Process

negative regulation of TORC1 s... 9 | 9
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sestrin-2 SESN2 Tbio Non-IDG -1.78334 73.0 151
Sestrin-3 SESN3 Tbio Non-IDG -1.06544 10.1 137
DEP domain-containing protein 5 DEPDC5 Tbio Non-IDG -1.45055 27.8 40
GATS-like protein 3 GATSL3 Tbio Non-IDG 0.00000 11
Sestrin-1 SESN1 Tbio Non-IDG -1.92579 76.1 153
Serine/threonine-protein kinase STK11 STK11 Tchem Kinase -2.91576 899.7 869
Serine-protein kinase ATM ATM Tchem Kinase -3.54059 3417.4 954
GATS-like protein 2 GATSL2 Tbio Non-IDG 0.00000 11
E3 ubiquitin-protein ligase RNF152 RNF152 Tbio Enzyme -0.29092 1.91 2