Development Level

Tbio 21 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
osteosarcoma 14 | 7,950
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
Kidney cancer 11 | 2,613
medulloblastoma, large-cell 10 | 6,241
psoriasis 9 | 6,694
Cancer 8 | 2,499
ependymoma 8 | 4,679
lung cancer 8 | 4,740
Breast cancer 7 | 3,578
Epilepsy 7 | 792
group 4 medulloblastoma 6 | 1,855
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Liver cancer 5 | 604
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Intellectual disability 4 | 1,016
Pneumothorax 4 | 23
Renal Cell Carcinoma 4 | 214
Schizophrenia 4 | 1,160
Seizures 4 | 596
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Attention deficit hyperactivity disorder 3 | 278
Epilepsy, Partial, with Variable Foci 3 | 3
Glucose Intolerance 3 | 19
Impaired glucose tolerance 3 | 28
Insulin Resistance 3 | 72
Kidney angiomyolipoma 3 | 8
Mood Disorders 3 | 184
Nerve Degeneration 3 | 121
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Tuberous sclerosis 3 | 19
Vascular disease 3 | 319
colon cancer 3 | 1,478
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abdominal Pain 2 | 98
Abnormal behavior 2 | 52
Abnormality of female internal genitalia 2 | 13
Autistic Disorder 2 | 364
Brain Diseases 2 | 24
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Renal Cell 2 | 124
Carcinoma, Squamous Cell 2 | 110
Cardiomegaly 2 | 116
Chest Pain 2 | 38
Cystic kidney 2 | 30
Dyspnea 2 | 76
Electroencephalogram abnormal 2 | 101
Fibromatosis, Gingival 2 | 8
Heart failure 2 | 162
Hereditary gingival fibromatosis 2 | 8
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Idiopathic gingival hyperplasia 2 | 8
Liver carcinoma 2 | 240
Lymphadenopathy 2 | 62
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Mouth Neoplasms 2 | 55
Myoclonic Epilepsies, Progressive 2 | 44
Phenotypic variability 2 | 150
Precocious Puberty 2 | 28
Prominent back of the head 2 | 21
Prominent occiput 2 | 21
Pulmonary emphysema 2 | 48
Renal cyst 2 | 30
Sebaceous adenoma 2 | 26
Specific learning disability 2 | 47
Squamous cell carcinoma 2 | 129
Unipolar Depression 2 | 250
West Syndrome 2 | 28
Wolff-Parkinson-White syndrome 2 | 19
hypopigmented skin patch 2 | 59

Tissue

Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 5 | 4,145
Kinase 4 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

GO Process

negative regulation of TOR sig... 29 | 29
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA damage-inducible transcript 4 protein DDIT4 Tbio Non-IDG -2.11497 150.3 231
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Tumor necrosis factor alpha-induced protein 8-like protein 1 TNFAIP8L1 Tdark Non-IDG -0.73715 7.59 32
E3 ubiquitin-protein ligase UBR1 UBR1 Tbio Enzyme -1.95732 91.8 136
Folliculin-interacting protein 1 FNIP1 Tbio Non-IDG -0.92010 6.73 74
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.31365 19.5 26
DEP domain-containing mTOR-interacting protein DEPTOR Tbio Non-IDG -1.61386 50.2 180
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein PREX2 Tbio Non-IDG -1.14909 15.8 39
Laforin, isoform 9 EPM2A Tbio Non-IDG -2.18932 282.5 0
Programmed cell death protein 6 PDCD6 Tbio Non-IDG -1.74455 59.1 235