Development Level

Tbio 19 | 10,625
Tchem 6 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Phenotype

decreased lumbar vertebrae num... 2 | 62
increased sacral vertebrae num... 2 | 62
preweaning lethality, incomple... 2 | 260
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal snout morphology 1 | 18
abnormal tooth morphology 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased KLRG1-positive T-hel... 1 | 2
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased NK cell number 1 | 16
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
enlarged spleen 1 | 26
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased CD8-positive, alpha-... 1 | 11
increased Ly6C low monocyte nu... 1 | 8
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased circulating alkaline... 1 | 119
increased or absent threshold ... 1 | 128
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
polydactyly 1 | 22
preweaning lethality, complete... 1 | 633

Disease

ovarian cancer 16 | 8,491
osteosarcoma 12 | 7,933
atypical teratoid / rhabdoid tumor 11 | 4,369
glioblastoma 11 | 5,572
Cancer 8 | 2,346
lung cancer 8 | 4,473
medulloblastoma, large-cell 8 | 6,234
psoriasis 8 | 6,685
Carcinoma 7 | 2,147
ependymoma 7 | 2,514
Epilepsy 6 | 346
oligodendroglioma 6 | 2,849
astrocytic glioma 5 | 2,241
medulloblastoma 5 | 1,524
primitive neuroectodermal tumor 5 | 3,031
Breast cancer 4 | 3,098
Intellectual disability 4 | 573
Neoplastic Syndromes, Hereditary 4 | 48
adrenocortical carcinoma 4 | 1,427
diabetes mellitus 4 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
juvenile dermatomyositis 4 | 1,189
Alzheimer's disease 3 | 644
Impaired glucose tolerance 3 | 12
Insulin Resistance 3 | 50
Kidney angiomyolipoma 3 | 8
Pick disease 3 | 1,893
Pneumothorax 3 | 17
Renal Cell Carcinoma 3 | 199
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
colon cancer 3 | 1,475
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
non primary Sjogren syndrome sicca 3 | 840
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,271
subependymal giant cell astrocytoma 3 | 2,287
Anemia 2 | 252
Angiomyolipoma 2 | 17
Autistic Disorder 2 | 320
Bipolar Disorder 2 | 266
Birt-Hogg-Dube syndrome 2 | 10
Brain Diseases 2 | 22
Cardiomegaly 2 | 66
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Johanson-Blizzard syndrome 2 | 4
Kidney cancer 2 | 121
Liver carcinoma 2 | 217
Lymphangioleiomyomatosis 2 | 17
Mammary Neoplasms 2 | 410
Metabolic syndrome X 2 | 155
Mouth Neoplasms 2 | 44
Myocardial Reperfusion Injury 2 | 34
Myoclonic Epilepsies, Progressive 2 | 12
Nerve Degeneration 2 | 73
Obesity 2 | 616
Oxyphilic adenoma 2 | 21
Pancreatic Neoplasm 2 | 79
Prostatic Neoplasms 2 | 471
RAPADILINO syndrome 2 | 7
Rheumatoid Arthritis 2 | 1,170
Schizophrenia 2 | 503
Squamous cell carcinoma 2 | 96
TUBEROUS SCLEROSIS 1 (disorder) 2 | 3
Tuberous Sclerosis 1 2 | 3
Tuberous sclerosis 2 | 18
Vascular disease 2 | 281
West Syndrome 2 | 24
acute quadriplegic myopathy 2 | 1,157
chronic lymphosyte leukemia 2 | 232
cystic fibrosis 2 | 1,670
gastric carcinoma 2 | 832
infantile epileptic encephalopathy 2 | 3
lung adenocarcinoma 2 | 2,714
lung carcinoma 2 | 2,844
malignant mesothelioma 2 | 3,163
non-small cell lung cancer 2 | 2,798
pilocytic astrocytoma 2 | 3,086
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis 2 | 1,563
tuberculosis and treatment for 3 months 2 | 327
ulcerative colitis 2 | 2,087
Conventional (Clear Cell) Renal Cell Carcinoma 1 | 7
Demyelinating Diseases 1 | 7
Hemangioma 1 | 35
Hyperglycemia 1 | 120
Neurofibromatosis 1 | 37
Paraganglioma 1 | 12
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 22
Renal Cell Carcinoma, Nonpapillary 1 | 7
Skin Neoplasms 1 | 49
Small cell carcinoma of lung 1 | 45
Stomach cancer 1 | 18
von Hippel-Lindau disease 1 | 11

Tissue

Blood and immune system 27 | 17,994
Cardiovascular System 27 | 17,957
Digestive Tract 27 | 18,472
Endocrine System 27 | 18,511
Female tissues 27 | 18,646
Liver and Pancreas 27 | 18,135
Male tissues 27 | 17,968
Nervous System 27 | 18,560
Urinary Tract 27 | 18,443
Respiratory system 26 | 17,483
Skin and soft tissues 26 | 18,114

Target Family

Non-IDG 15 | 11,969
Enzyme 5 | 4,146
Kinase 4 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

GO Process

negative regulation of TOR sig... 27 | 27
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 Tchem Kinase -1.87050 66.3 830
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.43962 2958.6 656
Programmed cell death protein 6 PDCD6 Tbio Non-IDG -1.71771 56.5 214
Hamartin TSC1 Tbio Non-IDG -2.23602 165.3 1376
Laforin, isoform 9 EPM2A Tbio Non-IDG -2.15393 254.1 0
Transmembrane protein 127 TMEM127 Tbio Non-IDG -1.22936 16.9 25
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.81704 52.3 722
Folliculin FLCN Tbio Non-IDG -2.57823 388.8 215
DEP domain-containing protein 5 DEPDC5 Tbio Non-IDG -1.45055 27.8 40
Tuberin TSC2 Tbio Non-IDG -2.96129 933.5 1483