Development Level

Tbio 26 | 10,625
Tchem 8 | 1,890
Tclin 3 | 602

IMPC Phenotype

preweaning lethality, incomple... 3 | 260
decreased lean body mass 2 | 195
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged spleen 1 | 26
hydroencephaly 1 | 6
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased circulating alanine ... 1 | 11
increased circulating potassiu... 1 | 31
increased mean corpuscular hem... 1 | 93
increased vertical activity 1 | 18
limb grasping 1 | 35
preweaning lethality, complete... 1 | 633
shortened PQ interval 1 | 6
small testis 1 | 37

Disease

ovarian cancer 19 | 8,491
psoriasis 18 | 6,685
Cancer 15 | 2,346
glioblastoma 15 | 5,572
lung cancer 14 | 4,473
osteosarcoma 14 | 7,933
Rheumatoid Arthritis 13 | 1,170
non-small cell lung cancer 13 | 2,798
lung carcinoma 12 | 2,844
interstitial cystitis 11 | 2,299
Asthma 10 | 349
Hypersensitivity reaction type II disease 10 | 235
Multiple Sclerosis 10 | 498
diabetes mellitus 10 | 1,663
medulloblastoma, large-cell 10 | 6,234
atypical teratoid / rhabdoid tumor 9 | 4,369
lung adenocarcinoma 9 | 2,714
sarcoidosis 9 | 368
ulcerative colitis 9 | 2,087
cutaneous lupus erythematosus 8 | 1,056
Berylliosis 7 | 28
Breast cancer 7 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
invasive ductal carcinoma 7 | 2,950
pancreatic cancer 7 | 2,300
pilocytic astrocytoma 7 | 3,086
systemic lupus erythematosus 7 | 172
tuberculosis 7 | 1,563
Human immunodeficiency virus infectious disease 6 | 129
IGA Glomerulonephritis 6 | 454
Liver disease 6 | 219
Type 1 diabetes mellitus 6 | 104
group 4 medulloblastoma 6 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
malignant mesothelioma 6 | 3,163
pediatric high grade glioma 6 | 2,712
spina bifida 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
Allergic rhinitis 5 | 92
Diabetes Mellitus, Insulin-Dependent 5 | 77
Diffuse cutaneous systemic sclerosis 5 | 17
Hepatitis B 5 | 103
Multiple Sclerosis, Susceptibility to 5 | 15
Narcolepsy 5 | 69
Narcolepsy-cataplexy 5 | 21
Prostatic Neoplasms 5 | 471
Rheumatoid Arthritis, Systemic Juvenile 5 | 16
Sarcoidosis 1 5 | 14
breast carcinoma 5 | 1,614
follicular lymphoma 5 | 17
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
limited scleroderma 5 | 19
Allergic hypersensitivity disease 4 | 123
Dermatitis 4 | 141
Graves' disease 4 | 25
Inflammation 4 | 109
Juvenile rheumatoid arthritis 4 | 105
Pick disease 4 | 1,893
Schizophrenia 4 | 503
Vasculitis 4 | 64
astrocytoma 4 | 1,493
cystic fibrosis 4 | 1,670
inflammatory breast cancer 4 | 404
mucosa-associated lymphoid tissue lymphoma 4 | 480
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 788
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
Adult T-Cell Lymphoma/Leukemia 3 | 30
Alzheimer's disease 3 | 644
Arthritis 3 | 248
Chronic obstructive pulmonary disease 3 | 147
Cleft palate 3 | 125
Crohn Disease 3 | 97
Crohn's disease 3 | 304
Eosinophilia 3 | 65
Heart disease 3 | 279
Hepatitis C 3 | 90
Inflammatory Bowel Diseases 3 | 87
Inflammatory bowel disease 3 | 142
Kidney disease 3 | 397
Leishmaniasis 3 | 49
Liver carcinoma 3 | 217
Lung Neoplasms 3 | 171
Lung disease 3 | 136
Malaria 3 | 140
Multiple myeloma 3 | 1,327
Neuropathy 3 | 210
Pancreatitis 3 | 97
Pneumonia 3 | 133
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,475
dermatomyositis 3 | 966
interstitial lung disease 3 | 292
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
non-small cell lung carcinoma 3 | 413
posterior fossa group A ependymoma 3 | 1,511

Tissue

Blood and immune system 33 | 17,994
Cardiovascular System 33 | 17,957
Digestive Tract 33 | 18,472
Endocrine System 33 | 18,511
Female tissues 33 | 18,646
Male tissues 33 | 17,968
Nervous System 33 | 18,560
Urinary Tract 33 | 18,443
Liver and Pancreas 32 | 18,135
Respiratory system 32 | 17,483
Skin and soft tissues 32 | 18,114

Target Family

Non-IDG 27 | 11,969
Enzyme 7 | 4,146
Transcription Factor 3 | 1,400

GO Process

negative regulation of T cell ... 37 | 37
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Group IID secretory phospholipase A2 PLA2G2D Tchem Enzyme -2.11153 121.4 103
Interleukin-20 receptor subunit beta IL20RB Tbio Non-IDG -1.50769 35.5 133
C-type lectin domain family 4 member G CLEC4G Tbio Non-IDG -1.14231 17.1 32
Interleukin-10 IL10 Tchem Non-IDG -4.07619 11514.6 1151
HLA class II histocompatibility antigen, DRB1-4 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
Tumor necrosis factor receptor superfamily member 21 TNFRSF21 Tbio Non-IDG -2.22642 176.1 352
Uteroglobin SCGB1A1 Tbio Non-IDG -2.89224 785.2 213
Forkhead box protein P3 FOXP3 Tbio Transcription Factor -3.77327 5680.3 1162
Leukocyte immunoglobulin-like receptor subfamily B member 1 LILRB1 Tbio Non-IDG -2.19367 168.2 0
Pulmonary surfactant-associated protein D SFTPD Tbio Non-IDG -2.78399 653.0 266