Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598

Disease

non-small cell lung cancer 5 | 2,890
Carcinoma 4 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Absent peripheral blood T cells 2 | 4
Autosomal recessive predisposition 2 | 1,442
Diarrhea 2 | 253
Eczema 2 | 45
Failure to thrive secondary to recurrent infections 2 | 4
Frequent opportunistic infections 2 | 5
Hepatomegaly 2 | 285
Hypersensitivity reaction type II disease 2 | 253
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Lymphadenopathy 2 | 62
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Otitis Media 2 | 52
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell Negative, B Cell Positive, NK Cell Positive 2 | 5
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Positive 2 | 2
Severe T lymphocytopenia 2 | 4
Severe combined immunodeficiency 2 | 51
Splenomegaly 2 | 190
Waldenstrons macroglobulinemia 2 | 765
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
non primary Sjogren syndrome sicca 2 | 891
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
Abortion, Spontaneous 1 | 109
Absence of eyebrows 1 | 31
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma 1 | 122
Alopecia 1 | 115
Anemia 1 | 365
Aplasia/Hypoplasia of the eyebrow 1 | 31
Arthritis 1 | 290
Atopic dermatitis 1 | 952
Dry skin 1 | 75
Endometriosis 1 | 540
Eosinophilia 1 | 28
Failure to gain weight 1 | 365
Fever 1 | 138
Heart disease 1 | 306
Hepatitis B 1 | 108
Hepatitis C 1 | 94
Hyperinsulinism 1 | 133
Inflammatory bowel disease 1 | 151
Kidney disease 1 | 430
Leber congenital amaurosis 1 | 69
Liver cancer 1 | 604
Lung Neoplasms 1 | 232
Lung disease 1 | 142
Lymphopenia 1 | 67
Pediatric failure to thrive 1 | 365
Peripheral vascular disease 1 | 87
Pick disease 1 | 1,894
Pneumonia 1 | 174
Pruritus 1 | 58
Psychotic Disorders 1 | 151
Retinal Diseases 1 | 55
Skin cancer 1 | 469
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Spontaneous abortion 1 | 113
Vascular disease 1 | 319
Xerosis 1 | 75
active Crohn's disease 1 | 922
aldosterone-producing adenoma 1 | 665
chronic kidney disease 1 | 90
chronic lymphosyte leukemia 1 | 204
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 966
medulloblastoma 1 | 720
nephrosclerosis 1 | 333
sarcoidosis 1 | 370
spina bifida 1 | 1,074
tuberculosis 1 | 2,010

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145

GO Process

negative regulation of T cell ... 5 | 5
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

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