Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal bone structure 2 | 187
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal midbrain morphology 1 | 10
absent pinna reflex 1 | 23
anophthalmia 1 | 33
aorta dilation 1 | 3
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased lactate dehydrogenas... 1 | 16
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hypoactivity 1 | 132
increased cardiac stroke volum... 1 | 1
increased lean body mass 1 | 172
prolonged QT interval 1 | 38
shortened QT interval 1 | 4

Disease

Carcinoma 16 | 11,493
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
adult high grade glioma 10 | 3,801
atypical teratoid / rhabdoid tumor 10 | 5,112
Breast cancer 9 | 3,578
Cancer 8 | 2,499
ependymoma 8 | 4,679
lung cancer 8 | 4,740
psoriasis 8 | 6,694
group 3 medulloblastoma 7 | 4,104
lung adenocarcinoma 7 | 2,716
Kidney cancer 6 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
Astrocytoma, Pilocytic 5 | 3,081
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Acquired scoliosis 4 | 281
Autosomal recessive predisposition 4 | 1,442
Curvature of spine 4 | 282
Muscle hypotonia 4 | 571
astrocytoma 4 | 1,146
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
primitive neuroectodermal tumor 4 | 3,035
Blepharoptosis 3 | 231
Cleft Palate 3 | 271
Dull intelligence 3 | 645
Epilepsy 3 | 792
Gaucher disease type 1 3 | 180
Hepatomegaly 3 | 285
Intellectual disability 3 | 1,016
LEOPARD syndrome 3 | 20
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurofibromatosis 3 | 40
Noonan syndrome 3 | 34
Optic Atrophy 3 | 242
Orbital separation excessive 3 | 244
Pick disease 3 | 1,894
Poor school performance 3 | 645
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Bleeding tendency 2 | 37
Byzanthine arch palate 2 | 194
Connective tissue disease 2 | 62
Craniofacial Abnormalities 2 | 151
Developmental regression 2 | 95
Downward slant of palpebral fissure 2 | 158
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Exophthalmos 2 | 112
Failure to gain weight 2 | 365
Glaucoma 2 | 239
Joint hyperflexibility 2 | 78
Kidney disease 2 | 430
Loss of developmental milestones 2 | 95
Lung Neoplasms 2 | 232
Mental deterioration in childhood 2 | 95
Muscle Weakness 2 | 170
Myocardial Infarction 2 | 151
Neurodevelopmental regression 2 | 95
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Skin cancer 2 | 469
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Nervous System 25 | 16,725
Skin and soft tissues 25 | 17,230
Blood and immune system 24 | 16,909
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Respiratory system 24 | 16,393
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 10 | 4,145
Kinase 2 | 634

GO Process

negative regulation of Ras pro... 25 | 25
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Ras GTPase-activating protein nGAP RASAL2 Tbio Enzyme -1.51440 33.0 99
Non-receptor tyrosine-protein kinase TNK1 TNK1 Tchem Kinase -0.79047 7.71 293
Ras GTPase-activating protein 4B RASA4B Tdark Enzyme 0.00000 0
Tripartite motif-containing protein 67 TRIM67 Tdark Non-IDG -2.01239 100.0 27
RAS protein activator like-3 RASAL3 Tbio Non-IDG -0.25123 2.81 57
Ras GTPase-activating protein 4 RASA4 Tbio Enzyme -2.47836 299.2 58
Rap guanine nucleotide exchange factor 1 RAPGEF1 Tbio Non-IDG -2.41980 281.2 167
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447