Development Level

Tbio 1 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
preweaning lethality, incomple... 1 | 499

Disease

Cancer 2 | 2,499
lung adenocarcinoma 2 | 2,716
ovarian cancer 2 | 8,520
Abdomen distended 1 | 43
Adverse reaction to drug 1 | 61
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Anemia 1 | 365
Arthritis 1 | 290
Brain disease 1 | 96
Breast cancer 1 | 3,578
Carcinoma 1 | 11,493
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis, Extrahepatic 1 | 25
Coarse facial features 1 | 108
Congenital hypothyroidism 1 | 26
Congenital omphalocele 1 | 20
Constipation 1 | 181
Delayed bone age 1 | 136
Diagnostic Test for Thyroid Dysfunction 1 | 3
Diaphragmatic Hernia 1 | 40
Drowsiness 1 | 7
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dry skin 1 | 75
Dyschezia 1 | 135
Endometriosis 1 | 540
Esophageal Squamous Cell Carcinoma 1 | 77
Feeding difficulties 1 | 127
Fever 1 | 138
Goiter 1 | 38
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
HYPOTHYROIDISM, CONGENITAL, NONGOITROUS, 6 1 | 1
Hemoglobin low 1 | 124
Hernia, Diaphragmatic 1 | 40
Hip Dislocation, Congenital 1 | 48
Hyperalgesia 1 | 83
Hyperlipidemia 1 | 43
Hypersensitivity reaction type II disease 1 | 253
Hyperthyroidism 1 | 53
Hyperthyroxinemia 1 | 9
Hypothyroidism 1 | 122
Icterus 1 | 82
Increased T3/T4 ratio 1 | 2
Inflammation 1 | 120
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Late tooth eruption 1 | 61
Lung disease 1 | 142
Macroglossia 1 | 65
Malignant tumor of thyroid gland 1 | 3
Mild Hypothyroidism 1 | 2
Multiple Organ Failure 1 | 8
Muscle hypotonia 1 | 571
Myocardial Infarction 1 | 151
Myocardial Ischemia 1 | 169
Myocardial Reperfusion Injury 1 | 37
Myxedema 1 | 11
Myxedema coma 1 | 2
Necrosis 1 | 53
Neuralgia 1 | 20
Neuropathy, Painful 1 | 2
Orbital separation excessive 1 | 244
Pancreatitis 1 | 123
Peripheral resistance to thyroid hormones 1 | 2
Peritonitis 1 | 43
Poor growth 1 | 114
Pulmonary Fibrosis 1 | 106
Relative macrocephaly 1 | 12
Sepsis 1 | 24
Simple goiter 1 | 2
Sleep disturbances 1 | 37
Squamous cell carcinoma of esophagus 1 | 77
Systemic Vasculitis 1 | 1
T3 Suppression for Thyroid Function Test 1 | 2
Thickened facial skin with coarse facial features 1 | 108
Thyroid Hormone Resistance Syndrome 1 | 5
Umbilical hernia 1 | 93
Vascular disease 1 | 319
Very poor growth 1 | 114
Wide bregma sutures 1 | 46
Xerosis 1 | 75
adult high grade glioma 1 | 3,801
atypical teratoid / rhabdoid tumor 1 | 5,112
breast carcinoma 1 | 1,638
diabetes mellitus 1 | 1,728
glioblastoma 1 | 5,792
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
osteosarcoma 1 | 7,950
primary pancreatic ductal adenocarcinoma 1 | 1,109
psoriasis 1 | 6,694
sonic hedgehog group medulloblastoma 1 | 467
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

negative regulation of RNA pol... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High mobility group protein B1 HMGB1 Tbio Transcription Factor -3.05199 2190.4 1145
Thyroid hormone receptor alpha THRA Tclin Nuclear Receptor -2.72292 527.4 453