Development Level

Tbio 60 | 11,445
Tchem 14 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
enlarged spleen 2 | 41
female infertility 2 | 60
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating phosphat... 2 | 26
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal esophagus morphology 1 | 5
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
thin ventricular wall 1 | 24
tremors 1 | 39

Disease

Carcinoma 50 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 38 | 7,950
psoriasis 34 | 6,694
lung cancer 30 | 4,740
Cancer 29 | 2,499
glioblastoma 26 | 5,792
non-small cell lung cancer 20 | 2,890
tuberculosis 19 | 2,010
ependymoma 18 | 4,679
Breast cancer 17 | 3,578
malignant mesothelioma 16 | 3,232
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
medulloblastoma, large-cell 15 | 6,241
Rheumatoid arthritis 14 | 1,191
adrenocortical carcinoma 14 | 1,428
atypical teratoid / rhabdoid tumor 14 | 5,112
invasive ductal carcinoma 14 | 2,951
group 3 medulloblastoma 13 | 4,104
lung adenocarcinoma 13 | 2,716
pancreatic cancer 13 | 2,398
subependymal giant cell astrocytoma 13 | 2,287
cystic fibrosis 12 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Astrocytoma, Pilocytic 11 | 3,081
Kidney cancer 11 | 2,613
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
ulcerative colitis 11 | 1,819
juvenile dermatomyositis 10 | 1,187
oligodendroglioma 10 | 2,850
pituitary cancer 10 | 1,972
cutaneous lupus erythematosus 9 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Bipolar Disorder 8 | 666
Liver Cirrhosis, Experimental 8 | 769
acute quadriplegic myopathy 8 | 1,158
Multiple myeloma 7 | 1,332
Obesity 7 | 678
Prostatic Neoplasms 7 | 495
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
primary Sjogren syndrome 7 | 735
primary pancreatic ductal adenocarcinoma 7 | 1,109
primitive neuroectodermal tumor 7 | 3,035
Arthritis 6 | 290
Asthma 6 | 385
Autosomal recessive predisposition 6 | 1,442
Melanoma 6 | 711
Multiple Sclerosis 6 | 540
Pick disease 6 | 1,894
Skin cancer 6 | 469
Vascular disease 6 | 319
astrocytic glioma 6 | 2,597
spina bifida 6 | 1,074
Arthritis, Rheumatoid 5 | 174
Atherosclerosis 5 | 291
Atopic dermatitis 5 | 952
Breast Neoplasms 5 | 445
Carcinoma, Hepatocellular 5 | 228
Crohn's disease 5 | 321
Inflammatory bowel disease 5 | 151
Kidney disease 5 | 430
Liver carcinoma 5 | 240
Liver disease 5 | 237
Mammary Neoplasms 5 | 425
Schizophrenia 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
dermatomyositis 5 | 966
esophageal adenocarcinoma 5 | 737
gastric carcinoma 5 | 807
group 4 medulloblastoma 5 | 1,855
hepatocellular carcinoma 5 | 547
Alzheimer's disease 4 | 658
Depressive disorder 4 | 409
Hypersensitivity reaction type II disease 4 | 253
Lung Neoplasms 4 | 232
Myocardial Infarction 4 | 151
Neoplasm Metastasis 4 | 168
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
colon cancer 4 | 1,478
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
Down syndrome 3 | 499
Glaucoma 3 | 239
Hepatomegaly 3 | 285
Lung disease 3 | 142
Malaria 3 | 160
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512

Tissue

Blood and immune system 72 | 16,909
Digestive Tract 72 | 17,369
Endocrine System 72 | 18,159
Female tissues 72 | 17,400
Skin and soft tissues 72 | 17,230
Respiratory system 71 | 16,393
Urinary Tract 71 | 16,678
Male tissues 70 | 17,142
Liver and Pancreas 69 | 16,750
Nervous System 68 | 16,725
Cardiovascular System 65 | 15,192

Target Family

Non-IDG 43 | 12,091
Enzyme 16 | 4,145
Transcription Factor 6 | 1,400
Kinase 5 | 634
Epigenetic 3 | 242
GPCR 2 | 408
Nuclear Receptor 1 | 48

GO Process

negative regulation of NF-kapp... 76 | 76
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
COMM domain-containing protein 7 COMMD7 Tbio Non-IDG -0.95317 9.82 82
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Transcription elongation factor A protein-like 7 TCEAL7 Tbio Non-IDG -0.70919 5.68 38
Tax1-binding protein 1 TAX1BP1 Tbio Non-IDG -1.44609 30.4 133
RWD domain-containing protein 3 RWDD3 Tbio Non-IDG -1.02793 10.9 98
Cactin CACTIN Tbio Non-IDG -1.26544 19.0 50
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686