Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

decreased body weight 2 | 161
decreased circulating alanine ... 2 | 47
decreased circulating creatini... 2 | 39
preweaning lethality, complete... 2 | 979
abnormal coat appearance 1 | 31
abnormal humerus morphology 1 | 11
abnormal vocalization 1 | 21
cataract 1 | 92
decreased circulating aspartat... 1 | 34
decreased circulating glycerol... 1 | 16
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
impaired pupillary reflex 1 | 26
increased heart weight 1 | 62

Disease

ovarian cancer 13 | 8,520
Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Cancer 8 | 2,499
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
glioblastoma 7 | 5,792
lung carcinoma 7 | 2,843
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
malignant mesothelioma 5 | 3,232
ependymoma 4 | 4,679
pancreatic cancer 4 | 2,398
Arthritis 3 | 290
Autosomal recessive predisposition 3 | 1,442
Big calvaria 3 | 147
Breast Neoplasms 3 | 445
Cataract 3 | 297
Cognitive delay 3 | 608
Down syndrome 3 | 499
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Highly variable severity 3 | 157
Hydrocephalus 3 | 152
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Neurofibromatosis 3 | 40
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Variable expressivity 3 | 157
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
group 3 medulloblastoma 3 | 4,104
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
urothelial carcinoma 3 | 318
Adenoma 2 | 167
Amyotrophic lateral sclerosis 2 | 451
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Concave bridge of nose 2 | 195
Contact Dermatitis 2 | 81
Creatine phosphokinase serum increased 2 | 110
Delayed speech and language development 2 | 112
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Dermatitis, Contact 2 | 71
Elevated creatine kinase 2 | 110
Epilepsy 2 | 792
Globe of eye large 2 | 20
Heart disease 2 | 306
Hypertension 2 | 396
Hypoplasia of corpus callosum 2 | 90
Language Delay 2 | 112
Liver cancer 2 | 604
Mental Depression 2 | 333
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Myocardial Ischemia 2 | 169
Myopathy 2 | 185
Pick disease 2 | 1,894
Polymicrogyria 2 | 48
Skin cancer 2 | 469
Speech Delay 2 | 112
Speech impairment 2 | 112
Stomach Neoplasms 2 | 300
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
dermatomyositis 2 | 966
fibroadenoma 2 | 559
limb-girdle muscular dystrophy 2 | 37
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 17 | 18,159
Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Nervous System 15 | 16,725

Target Family

Enzyme 8 | 4,145
Non-IDG 7 | 12,091
Epigenetic 1 | 242
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

negative regulation of MAPK ca... 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
E3 ubiquitin-protein ligase RNF149 RNF149 Tdark Enzyme -0.10751 1.33 123
LEM domain-containing protein 2 LEMD2 Tdark Non-IDG -0.53782 3.95 95
Protein CASC2, isoform 3 CASC2 Tbio Non-IDG 0.00000 0
Neurofibromin NF1 Tbio Non-IDG -3.60161 4054.2 355
Serine/threonine-protein phosphatase with EF-hands 2 PPEF2 Tbio Enzyme -0.26680 1.77 58
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.93963 79.1 299
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Histone-lysine N-methyltransferase ASH1L ASH1L Tbio Epigenetic -1.28102 19.8 111
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272