Development Level

Tbio 27 | 11,445
Tchem 10 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 2 | 187
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
limb grasping 1 | 41

Disease

Carcinoma 36 | 11,493
ovarian cancer 28 | 8,520
osteosarcoma 24 | 7,950
psoriasis 22 | 6,694
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
lung cancer 17 | 4,740
Breast cancer 16 | 3,578
medulloblastoma, large-cell 16 | 6,241
adult high grade glioma 15 | 3,801
ependymoma 15 | 4,679
Kidney cancer 11 | 2,613
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 11 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
malignant mesothelioma 11 | 3,232
Cancer 10 | 2,499
breast carcinoma 10 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
Astrocytoma, Pilocytic 9 | 3,081
adrenocortical carcinoma 9 | 1,428
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
subependymal giant cell astrocytoma 9 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
spina bifida 8 | 1,074
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Rheumatoid arthritis 7 | 1,191
cystic fibrosis 7 | 1,696
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
ulcerative colitis 7 | 1,819
Asthma 6 | 385
Carcinoma, Hepatocellular 6 | 228
Liver carcinoma 6 | 240
Vascular disease 6 | 319
colon cancer 6 | 1,478
group 3 medulloblastoma 6 | 4,104
pituitary cancer 6 | 1,972
Acquired metabolic disease 5 | 336
Alzheimer's disease 5 | 658
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Lung Neoplasms 5 | 232
active Crohn's disease 5 | 922
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
pancreatic cancer 5 | 2,398
primary Sjogren syndrome 5 | 735
primitive neuroectodermal tumor 5 | 3,035
Adenocarcinoma 4 | 122
Arthritis 4 | 290
Autistic Disorder 4 | 364
Depressive disorder 4 | 409
Heart disease 4 | 306
Liver Cirrhosis, Experimental 4 | 769
Liver neoplasms 4 | 130
Obesity 4 | 678
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Stomach Neoplasms 4 | 300
Systemic lupus erythematosus 4 | 194
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
esophageal adenocarcinoma 4 | 737
juvenile dermatomyositis 4 | 1,187
oligodendroglioma 4 | 2,850
sarcoidosis 4 | 370
Amyotrophic lateral sclerosis 3 | 451
Arthritis, Rheumatoid 3 | 174
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Chemical and Drug Induced Liver Injury 3 | 195
Cognitive delay 3 | 608
Coronary artery disease 3 | 268
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Disease Progression 3 | 136
Fatty liver disease 3 | 103
Gaucher disease type 1 3 | 180
Liver disease 3 | 237
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Myocardial Ischemia 3 | 169
Neoplasm Metastasis 3 | 168
Osteoporosis 3 | 363
Pick disease 3 | 1,894
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
fibroadenoma 3 | 559
non-small cell lung carcinoma 3 | 317
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Nervous System 39 | 16,725
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 10 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634
Nuclear Receptor 3 | 48
Transcription Factor 1 | 1,400

GO Process

negative regulation of I-kappa... 41 | 41
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tripartite motif-containing protein 59 TRIM59 Tbio Non-IDG -0.95825 14.1 122
Endoribonuclease ZC3H12A ZC3H12A Tbio Enzyme -1.81028 77.8 134
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
NLR family CARD domain-containing protein 3 NLRC3 Tbio Non-IDG 0.00000 29
NACHT, LRR and PYD domains-containing protein 6 NLRP6 Tbio Non-IDG -2.91735 806.9 177
NACHT, LRR and PYD domains-containing protein 12 NLRP12 Tbio Non-IDG -2.42691 247.9 268
OTU domain-containing protein 7A OTUD7A Tbio Non-IDG -0.54041 3.76 78
Serine/threonine-protein kinase RIO3 RIOK3 Tchem Kinase -1.08927 12.4 142
TRAF family member-associated NF-kappa-B activator TANK Tbio Non-IDG -1.81992 67.5 373
Histone-lysine N-methyltransferase ASH1L ASH1L Tbio Epigenetic -1.28102 19.8 111