Development Level

Tbio 31 | 11,445
Tchem 2 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
decreased total body fat amoun... 2 | 207
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
cardiovascular system phenotyp... 1 | 36
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
female infertility 1 | 60
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112

Disease

Carcinoma 24 | 11,493
ovarian cancer 17 | 8,520
medulloblastoma, large-cell 15 | 6,241
osteosarcoma 15 | 7,950
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
lung cancer 11 | 4,740
non-small cell lung cancer 11 | 2,890
Breast cancer 10 | 3,578
Cancer 10 | 2,499
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
psoriasis 10 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
Astrocytoma, Pilocytic 6 | 3,081
adult high grade glioma 6 | 3,801
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
Cognitive delay 4 | 608
Dull intelligence 4 | 645
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Melanoma 4 | 711
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
diabetes mellitus 4 | 1,728
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Asthma 3 | 385
Autosomal recessive predisposition 3 | 1,442
Cryptorchidism 3 | 296
Cystic kidney 3 | 30
Lung Neoplasms 3 | 232
Mental Depression 3 | 333
Multiple myeloma 3 | 1,332
Neurofibromatosis 3 | 40
Obesity 3 | 678
Pick disease 3 | 1,894
Renal cyst 3 | 30
Retinal Degeneration 3 | 106
Short stature 3 | 531
Specific learning disability 3 | 47
Strabismus 3 | 270
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis and treatment for 6 months 3 | 409
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Carcinoma, Hepatocellular 2 | 228
Delayed speech and language development 2 | 112
Depressive disorder 2 | 409
Down syndrome 2 | 499
Electroencephalogram abnormal 2 | 101
Epilepsy 2 | 792
Infantile onset 2 | 238
Kidney disease 2 | 430
Language Delay 2 | 112
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Major Depressive Disorder 2 | 301
Mouth Neoplasms 2 | 55
Orofacial cleft 2 | 54
Parkinson's disease 2 | 392
Seizures 2 | 596
Speech Delay 2 | 112
Speech impairment 2 | 112
Unipolar Depression 2 | 250
Vascular disease 2 | 319
esophageal adenocarcinoma 2 | 737
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Digestive Tract 32 | 17,369
Endocrine System 32 | 18,159
Female tissues 32 | 17,400
Liver and Pancreas 32 | 16,750
Male tissues 32 | 17,142
Nervous System 32 | 16,725
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Urinary Tract 32 | 16,678

Target Family

Non-IDG 24 | 12,091
Enzyme 7 | 4,145
GPCR 1 | 408
Kinase 1 | 634

GO Process

negative regulation of GTPase ... 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
NKG2-D type II integral membrane protein KLRK1 Tbio Non-IDG -1.53824 32.8 425
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Ras GTPase-activating protein 4 RASA4 Tbio Enzyme -2.47836 299.2 58
Adenosine monophosphate-protein transferase FICD FICD Tbio Enzyme -3.09864 1214.1 174
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 ARFGEF1 Tbio Non-IDG -0.85174 8.71 57
Radixin RDX Tbio Non-IDG -2.47844 221.4 333
Angiomotin AMOT Tbio Non-IDG -1.75932 64.8 318
Cytoplasmic polyadenylation element-binding protein 2 CPEB2 Tbio Non-IDG -0.98921 8.38 85