Development Level

Tbio 47 | 11,445
Tchem 5 | 1,598
Tclin 5 | 613
Tdark 3 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal kidney morphology 1 | 65
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2

Disease

ovarian cancer 43 | 8,520
Multiple myeloma 28 | 1,332
lung cancer 28 | 4,740
Carcinoma 23 | 11,493
psoriasis 23 | 6,694
osteosarcoma 21 | 7,950
glioblastoma 19 | 5,792
HIV Infections 15 | 102
Cancer 14 | 2,499
Breast cancer 13 | 3,578
dermatomyositis 11 | 966
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
ependymoma 10 | 4,679
invasive ductal carcinoma 10 | 2,951
malignant mesothelioma 10 | 3,232
medulloblastoma, large-cell 10 | 6,241
Waldenstrons macroglobulinemia 9 | 765
atypical teratoid / rhabdoid tumor 9 | 5,112
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
adult high grade glioma 7 | 3,801
astrocytoma 7 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
non primary Sjogren syndrome sicca 7 | 891
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
group 3 medulloblastoma 6 | 4,104
tuberculosis 6 | 2,010
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
lung carcinoma 5 | 2,843
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
Anemia 3 | 365
Mammary Neoplasms, Experimental 3 | 154
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
Stevens-Johnson syndrome 3 | 92
active Crohn's disease 3 | 922
breast carcinoma 3 | 1,638
chronic kidney disease 3 | 90
cutaneous lupus erythematosus 3 | 1,057
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
primitive neuroectodermal tumor 3 | 3,035
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Atopic dermatitis 2 | 952
Attention deficit hyperactivity disorder 2 | 278
COPD 2 | 118
Cockayne syndrome 2 | 60
Congestive heart failure 2 | 113
Esophageal Squamous Cell Carcinoma 2 | 77
Failure to gain weight 2 | 365
Hypoplastic mandible condyle 2 | 275
Intellectual disability 2 | 1,016
Joint stiffness 2 | 84
Mammary Neoplasms, Animal 2 | 136
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Peripheral Nervous System Diseases 2 | 52
Peripheral Neuropathy 2 | 134
Pick's disease 2 | 15
Radioulnar synostosis 2 | 35
Short neck 2 | 140
Skeletal muscle atrophy 2 | 139
Squamous cell carcinoma of esophagus 2 | 77
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
hepatocellular carcinoma 2 | 547
inflammatory breast cancer 2 | 286
muscle degeneration 2 | 139
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Frequent falls 1 | 12
Gait, Drop Foot 1 | 24
Reducing-body myopathy 1 | 1
Scapuloperoneal weakness 1 | 3
X-Linked Emery-Dreifuss Muscular Dystrophy 1 | 3

Tissue

Endocrine System 60 | 18,159
Blood and immune system 59 | 16,909
Digestive Tract 59 | 17,369
Female tissues 59 | 17,400
Male tissues 59 | 17,142
Nervous System 59 | 16,725
Respiratory system 59 | 16,393
Urinary Tract 59 | 16,678
Cardiovascular System 58 | 15,192
Liver and Pancreas 58 | 16,750
Skin and soft tissues 58 | 17,230

Target Family

Enzyme 42 | 4,145
Non-IDG 15 | 12,091
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

negative regulation of G2-M tr... 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Probable G-protein coupled receptor 132 GPR132 Tchem GPCR -2.72228 494.8 185
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
26S proteasome regulatory subunit 10B PSMC6 Tbio Enzyme -2.65165 339.0 214