Development Level

Tbio 29 | 11,445
Tchem 8 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
decreased blood urea nitrogen ... 2 | 51
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
vertebral transformation 2 | 12
abnormal bone mineralization 1 | 38
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal iris morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
male infertility 1 | 123
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 27 | 11,493
ovarian cancer 27 | 8,520
osteosarcoma 22 | 7,950
group 3 medulloblastoma 20 | 4,104
Cancer 17 | 2,499
medulloblastoma, large-cell 15 | 6,241
glioblastoma 14 | 5,792
atypical teratoid / rhabdoid tumor 13 | 5,112
lung cancer 13 | 4,740
psoriasis 13 | 6,694
Breast cancer 12 | 3,578
ependymoma 12 | 4,679
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 11 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
adult high grade glioma 9 | 3,801
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
Pick disease 7 | 1,894
breast carcinoma 7 | 1,638
nasopharyngeal carcinoma 7 | 1,058
non-small cell lung cancer 7 | 2,890
Kidney cancer 6 | 2,613
Rheumatoid arthritis 6 | 1,191
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
dermatomyositis 6 | 966
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
Breast Neoplasms 5 | 445
Mammary Neoplasms 5 | 425
acute quadriplegic myopathy 5 | 1,158
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
Intellectual disability 4 | 1,016
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
astrocytoma 4 | 1,146
juvenile dermatomyositis 4 | 1,187
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Endometriosis 3 | 540
Global developmental delay 3 | 608
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Nijmegen breakage syndrome 3 | 24
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
Waldenstrons macroglobulinemia 3 | 765
cystic fibrosis and chronic rhinosinusitis 3 | 214
esophageal adenocarcinoma 3 | 737
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Anemia 2 | 365
Aortic aneurysm 2 | 38
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Hepatocellular 2 | 228
Colorectal Neoplasms 2 | 243
Craniosynostosis 2 | 74
Curvature of spine 2 | 282
Downward slant of palpebral fissure 2 | 158
Endometrial Neoplasms 2 | 55
Facioscapulohumeral muscular dystrophy 2 | 26
Glaucoma 2 | 239
Glioma 2 | 74
Hypoplastic mandible condyle 2 | 275
Kleefstra syndrome 2 | 12
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
MYELODYSPLASTIC SYNDROME 2 | 53
Melanoma 2 | 711
Myelodysplastic Syndromes 2 | 26
Prostate cancer 2 | 175
Retinoblastoma 2 | 19
Retrognathia 2 | 54
Schizophrenia 2 | 1,160
Seckel syndrome 2 | 34
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
diabetes mellitus 2 | 1,728
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
tuberculosis and treatment for 6 months 2 | 409

Tissue

Blood and immune system 38 | 16,909
Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Cardiovascular System 37 | 15,192
Liver and Pancreas 37 | 16,750
Urinary Tract 37 | 16,678

Target Family

Non-IDG 17 | 12,091
Transcription Factor 7 | 1,400
Enzyme 6 | 4,145
Epigenetic 6 | 242
Kinase 2 | 634

GO Process

negative regulation of G0 to G... 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
MAX gene-associated protein MGA Tbio Transcription Factor -0.85532 6.90 42
Forkhead box protein O4 FOXO4 Tbio Transcription Factor -2.43923 278.0 720
Double homeobox protein 4 DUX4 Tbio Non-IDG 0.00000 153
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Enhancer of polycomb homolog 1 EPC1 Tbio Non-IDG -1.32335 19.2 62
Cell division cycle 7-related protein kinase CDC7 Tchem Kinase -2.24065 184.7 222
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -3.04423 1089.6 1375
Histone-lysine N-methyltransferase EHMT2 EHMT2 Tchem Epigenetic -2.49970 327.4 277
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform PPP2R5B Tbio Enzyme -0.59131 2.64 81