Development Level

Tbio 42 | 11,445
Tchem 15 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal gait 2 | 69
decreased T cell number 2 | 15
decreased circulating glucose ... 2 | 126
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
thrombocytopenia 2 | 56
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal heart shape 1 | 5
abnormal humerus morphology 1 | 11
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgG1 level 1 | 8
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased spleen weight 1 | 10
increased startle reflex 1 | 112
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 40 | 11,493
ovarian cancer 37 | 8,520
Cancer 33 | 2,499
osteosarcoma 33 | 7,950
glioblastoma 32 | 5,792
psoriasis 32 | 6,694
medulloblastoma, large-cell 28 | 6,241
lung cancer 27 | 4,740
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 23 | 4,679
Breast cancer 22 | 3,578
invasive ductal carcinoma 21 | 2,951
malignant mesothelioma 20 | 3,232
non-small cell lung cancer 19 | 2,890
pancreatic cancer 19 | 2,398
Astrocytoma, Pilocytic 18 | 3,081
adult high grade glioma 18 | 3,801
group 4 medulloblastoma 18 | 1,855
lung carcinoma 18 | 2,843
lung adenocarcinoma 17 | 2,716
pituitary cancer 17 | 1,972
breast carcinoma 16 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
tuberculosis 16 | 2,010
adrenocortical carcinoma 15 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
group 3 medulloblastoma 13 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
oligodendroglioma 13 | 2,850
ulcerative colitis 13 | 1,819
astrocytic glioma 12 | 2,597
cystic fibrosis 12 | 1,696
diabetes mellitus 12 | 1,728
ductal carcinoma in situ 12 | 1,745
interstitial cystitis 12 | 2,312
juvenile dermatomyositis 12 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
primitive neuroectodermal tumor 12 | 3,035
colon cancer 11 | 1,478
subependymal giant cell astrocytoma 11 | 2,287
Pick disease 10 | 1,894
Prostatic Neoplasms 9 | 495
Rheumatoid arthritis 9 | 1,191
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
pediatric high grade glioma 9 | 1,064
Kidney cancer 8 | 2,613
Liver Cirrhosis, Experimental 8 | 769
Schizophrenia 8 | 1,160
dermatomyositis 8 | 966
fibroadenoma 8 | 559
primary pancreatic ductal adenocarcinoma 8 | 1,109
Breast Neoplasms 7 | 445
Down syndrome 7 | 499
Mammary Neoplasms 7 | 425
Obesity 7 | 678
active Crohn's disease 7 | 922
aldosterone-producing adenoma 7 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
cutaneous lupus erythematosus 7 | 1,057
esophageal adenocarcinoma 7 | 737
gastric carcinoma 7 | 807
Asthma 6 | 385
Atopic dermatitis 6 | 952
Duchenne muscular dystrophy 6 | 601
Mental Depression 6 | 333
Multiple myeloma 6 | 1,332
Vascular disease 6 | 319
active ulcerative colitis 6 | 764
gastric cancer 6 | 459
nasopharyngeal carcinoma 6 | 1,058
pancreatic carcinoma 6 | 562
spina bifida 6 | 1,074
Amyotrophic lateral sclerosis 5 | 451
Arthritis 5 | 290
Bipolar Disorder 5 | 666
Depressive disorder 5 | 409
Endometriosis 5 | 540
Hypertension 5 | 396
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Myocardial Ischemia 5 | 169
Stomach Neoplasms 5 | 300
chronic rhinosinusitis 5 | 512
hepatocellular carcinoma 5 | 547
Autistic Disorder 4 | 364
Barrett's esophagus 4 | 182
Carcinoma, Hepatocellular 4 | 228
Carcinoma, Renal Cell 4 | 124
Craniofacial Abnormalities 4 | 151
Fatty liver disease 4 | 103
Hypertensive disease 4 | 292
Inflammation 4 | 120
Insulin Resistance 4 | 72
Liver carcinoma 4 | 240
Melanoma 4 | 711
Polycystic ovary syndrome 4 | 360
Renal Cell Carcinoma 4 | 214
Skin cancer 4 | 469
limb girdle muscular dystrophy 2I 4 | 32

Tissue

Endocrine System 60 | 18,159
Digestive Tract 59 | 17,369
Skin and soft tissues 59 | 17,230
Urinary Tract 59 | 16,678
Blood and immune system 58 | 16,909
Female tissues 58 | 17,400
Liver and Pancreas 58 | 16,750
Male tissues 58 | 17,142
Nervous System 58 | 16,725
Respiratory system 58 | 16,393
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 31 | 12,091
Enzyme 15 | 4,145
Kinase 7 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Transporter 1 | 473

GO Process

negative regulation of ERK1 an... 60 | 60
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Beta-crystallin A3 CRYBA1 Tbio Non-IDG -1.45158 27.2 133
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Ribosomal protein S6 kinase alpha-6 RPS6KA6 Tchem Kinase -1.26563 21.6 158
Serine/threonine-protein kinase WNK2 WNK2 Tchem Kinase -0.94627 9.07 108
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
Protein C3orf33 C3orf33 Tbio Non-IDG -0.33579 3.12 45
Rap guanine nucleotide exchange factor 1 RAPGEF1 Tbio Non-IDG -2.41980 281.2 167