Development Level

Tchem 7 | 1,598
Tbio 6 | 11,445

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
small spleen 2 | 19
abnormal behavior 1 | 298
abnormal heart left ventricle ... 1 | 16
decreased grip strength 1 | 116
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
preweaning lethality, complete... 1 | 979
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5

Disease

Cancer 10 | 2,499
Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
juvenile dermatomyositis 6 | 1,187
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
Down syndrome 5 | 499
Neoplasm Metastasis 5 | 168
glioblastoma 5 | 5,792
malignant mesothelioma 5 | 3,232
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Duchenne muscular dystrophy 4 | 601
Kidney disease 4 | 430
Neoplasm Invasiveness 4 | 161
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
invasive ductal carcinoma 4 | 2,951
Carcinoma, Non-Small-Cell Lung 3 | 107
Heart disease 3 | 306
Multiple myeloma 3 | 1,332
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Stomach Neoplasms 3 | 300
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Acute kidney injury 2 | 70
Alzheimer's disease 2 | 658
Arthritis 2 | 290
Atherosclerosis 2 | 291
Autistic Disorder 2 | 364
Autoimmune Diseases 2 | 67
Becker muscular dystrophy 2 | 191
Brain infarction 2 | 22
Bunion 2 | 26
Cell Transformation, Neoplastic 2 | 97
Colitis 2 | 54
Colonic Neoplasms 2 | 142
HIV Infections 2 | 102
Hallux Valgus 2 | 26
Hypersensitivity reaction type II disease 2 | 253
Inflammatory bowel disease 2 | 151
Liver Cirrhosis, Experimental 2 | 769
Mammary Neoplasms, Experimental 2 | 154
Metabolic syndrome X 2 | 52
Neoplastic Cell Transformation 2 | 89
Nerve Degeneration 2 | 121
Pancreatic Neoplasm 2 | 85
Schizophrenia 2 | 1,160
Small head 2 | 374
Thyroid cancer, papillary 2 | 14
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
limb girdle muscular dystrophy 2A 2 | 213
nephrosclerosis 2 | 333
oligodendroglioma 2 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Brain Neoplasms 1 | 33
Demyelinating Diseases 1 | 7
Diabetic retinopathy 1 | 56
Encephalopathy, progressive 1 | 6
Fascioliasis 1 | 17
Heart Diseases 1 | 43
Li-Fraumeni syndrome 1 | 13
Lung Injury 1 | 20
Malignant neoplasm of skin 1 | 15
Memory Disorders 1 | 40
Myocardial Reperfusion Injury 1 | 37
Nervous System Neoplasms 1 | 8
Neurodegenerative Diseases 1 | 38
Premature canities 1 | 24
Progressive brain disease 1 | 6
Schistosomiasis 1 | 35
Skin Neoplasms 1 | 69
Tumors of Adrenal Cortex 1 | 3

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 4 | 12,091
Transcription Factor 3 | 1,400
Enzyme 2 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634

GO Process

negative regulation of DNA dam... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.68760 506.6 336
Pituitary tumor-transforming gene 1 protein-interacting protein PTTG1IP Tbio Non-IDG -0.92138 9.13 94
Dual specificity tyrosine-phosphorylation-regulated kinase 3 DYRK3 Tchem Kinase -1.46121 29.1 191
Zinc finger protein SNAI2 SNAI2 Tbio Transcription Factor -3.25853 1689.4 685
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.28636 1782.9 566
Macrophage migration inhibitory factor MIF Tchem Non-IDG -3.21333 1538.5 527
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.41690 2313.9 1252
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.91883 8025.6 425
HLA class II histocompatibility antigen gamma chain CD74 Tchem Non-IDG -2.44232 286.2 1032
CD44 antigen CD44 Tbio Non-IDG -3.85987 6832.7 3401