Development Level

Tbio 36 | 11,445
Tchem 6 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal bone structure 2 | 187
abnormal iris morphology 2 | 13
decreased body weight 2 | 161
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal eyelid morphology 1 | 7
abnormal head size 1 | 6
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal placement of pupils 1 | 6
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
corneal opacity 1 | 32
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged testis 1 | 6
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
kinked tail 1 | 2
limb grasping 1 | 41
mammalian phenotype 1 | 17
narrow eye opening 1 | 12
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 29 | 11,493
medulloblastoma, large-cell 22 | 6,241
ovarian cancer 22 | 8,520
osteosarcoma 21 | 7,950
Cancer 19 | 2,499
ependymoma 18 | 4,679
glioblastoma 18 | 5,792
psoriasis 18 | 6,694
Breast cancer 17 | 3,578
atypical teratoid / rhabdoid tumor 17 | 5,112
group 3 medulloblastoma 15 | 4,104
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung carcinoma 13 | 2,843
Pick disease 12 | 1,894
lung cancer 12 | 4,740
pancreatic cancer 12 | 2,398
Astrocytoma, Pilocytic 11 | 3,081
adult high grade glioma 11 | 3,801
ductal carcinoma in situ 11 | 1,745
ulcerative colitis 11 | 1,819
astrocytic glioma 10 | 2,597
cystic fibrosis 10 | 1,696
subependymal giant cell astrocytoma 10 | 2,287
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
primary pancreatic ductal adenocarcinoma 8 | 1,109
primitive neuroectodermal tumor 8 | 3,035
tuberculosis 8 | 2,010
Myopia 7 | 176
colon cancer 7 | 1,478
oligodendroglioma 7 | 2,850
pituitary cancer 7 | 1,972
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Cognitive delay 6 | 608
Down syndrome 6 | 499
Global developmental delay 6 | 608
Mammary Neoplasms 6 | 425
Mental and motor retardation 6 | 608
Orbital separation excessive 6 | 244
Short stature 6 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric carcinoma 6 | 807
group 4 medulloblastoma 6 | 1,855
malignant mesothelioma 6 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
Astigmatism 5 | 54
Brachydactyly 5 | 156
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
Atopic dermatitis 4 | 952
Colorectal Neoplasms 4 | 243
Craniofacial Abnormalities 4 | 151
Decreased projection of midface 4 | 105
Duchenne muscular dystrophy 4 | 601
Gait abnormality 4 | 135
Holoprosencephaly 4 | 56
Hypotrophic midface 4 | 105
Kidney cancer 4 | 2,613
Midface retrusion 4 | 105
Osteoporosis 4 | 363
Pulmonary Fibrosis 4 | 106
Small midface 4 | 105
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
atypical teratoid/rhabdoid tumor 4 | 357
chronic rhinosinusitis 4 | 512
fibroadenoma 4 | 559
progressive supranuclear palsy 4 | 676
Acquired scoliosis 3 | 281
Arthritis 3 | 290
Broad flat nasal bridge 3 | 236
Curvature of spine 3 | 282
Depressed nasal bridge 3 | 195
Failure to gain weight 3 | 365
Nasal bridge wide 3 | 236
Pectus excavatum 3 | 100
Pediatric failure to thrive 3 | 365
Schizophrenia 3 | 1,160
Strabismus 3 | 270
Umbilical hernia 3 | 93
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
limb girdle muscular dystrophy 2A 3 | 213
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
spina bifida 3 | 1,074

Tissue

Digestive Tract 45 | 17,369
Endocrine System 45 | 18,159
Liver and Pancreas 45 | 16,750
Urinary Tract 45 | 16,678
Female tissues 44 | 17,400
Nervous System 44 | 16,725
Skin and soft tissues 44 | 17,230
Male tissues 43 | 17,142
Blood and immune system 42 | 16,909
Respiratory system 42 | 16,393
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242
GPCR 1 | 408

GO Process

negative regulation of BMP sig... 47 | 47
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTD small phosphatase-like protein 2 CTDSPL2 Tdark Enzyme -0.57403 3.70 102
SKI family transcriptional corepressor 2 SKOR2 Tbio Non-IDG -0.52843 4.42 59
BMP-binding endothelial regulator protein BMPER Tbio Non-IDG -2.51174 317.7 120
Neuroblastoma suppressor of tumorigenicity 1 NBL1 Tbio Non-IDG -2.58132 362.9 217
Inner nuclear membrane protein Man1 LEMD3 Tbio Non-IDG -2.30311 196.6 73
Mothers against decapentaplegic homolog 6 SMAD6 Tbio Transcription Factor -2.07569 106.7 450
E3 ubiquitin-protein ligase TRIM33 TRIM33 Tbio Epigenetic -3.10754 1197.2 297
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -2.03522 125.4 122
LEM domain-containing protein 2 LEMD2 Tdark Non-IDG -0.53782 3.95 95
RNA-binding protein with multiple splicing 2 RBPMS2 Tbio Non-IDG -0.50060 3.69 81