Development Level

Tbio 2 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal heart morphology 1 | 162
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased hemoglobin content 1 | 68
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased lean body mass 1 | 172
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 3 | 11,493
breast carcinoma 3 | 1,638
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
Acquired metabolic disease 2 | 336
Breast cancer 2 | 3,578
Kidney cancer 2 | 2,613
atypical teratoid / rhabdoid tumor 2 | 5,112
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
Abnormality of the fingernails 1 | 51
Abnormality of the ulna 1 | 10
Adenocarcinoma 1 | 122
Amyotrophic lateral sclerosis 1 | 451
Arthritis, Juvenile 1 | 126
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Big calvaria 1 | 147
Bilateral fifth finger clinodactyly 1 | 110
Bipolar Disorder 1 | 666
Brachydactyly 1 | 156
COPD 1 | 118
Cancer 1 | 2,499
Carcinoma, Renal Cell 1 | 124
Cardiovascular system disease 1 | 246
Carpal bone anomalies 1 | 5
Cell Transformation, Neoplastic 1 | 97
Chromosome Aberrations 1 | 16
Clubfoot 1 | 39
Colonic Neoplasms 1 | 142
Colorectal Neoplasms 1 | 243
Congenital clubfoot 1 | 109
Constipation 1 | 181
Coronary Disease 1 | 25
Curvature of little finger 1 | 110
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Diabetes Mellitus, Type 2 1 | 142
Diarrhea 1 | 253
Duchenne muscular dystrophy 1 | 601
Erythrocytosis, Familial, 4 1 | 1
Facioscapulohumeral muscular dystrophy 1 | 26
Fifth finger camptodactyly 1 | 3
Flexion contracture - elbow 1 | 32
Gestational diabetes 1 | 26
Hematocrit increased 1 | 5
Hemoglobin increased 1 | 6
Hyperglycemia 1 | 137
Hyperplasia 1 | 27
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Joint stiffness 1 | 84
Juvenile arthritis 1 | 126
Metabolic syndrome X 1 | 52
Neoplastic Cell Transformation 1 | 89
Neurodevelopmental Disorders 1 | 70
Persistent generalized lymphadenopathy 1 | 15
Pick disease 1 | 1,894
Pituitary hypoplasia 1 | 23
Polycythemia 1 | 25
Primary polycythemia 1 | 8
Radial aplasia/hypoplasia 1 | 29
Renal Cell Carcinoma 1 | 214
Schizoaffective Disorder 1 | 55
Schizophrenia 1 | 1,160
Septooptic dysplasia 1 | 19
Testicular Germ Cell Tumor 1 | 14
Type 2 diabetes mellitus 1 | 272
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
dermatomyositis 1 | 966
diabetes mellitus 1 | 1,728
fascioscapulohumeral muscular dystrophy 1 | 100
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
mucosa-associated lymphoid tissue lymphoma 1 | 484
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
sonic hedgehog group medulloblastoma 1 | 467
spina bifida 1 | 1,074
tuberculosis 1 | 2,010

Tissue

Blood and immune system 3 | 16,909
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678
Cardiovascular System 2 | 15,192

Target Family

Transcription Factor 2 | 1,400
Non-IDG 1 | 12,091

GO Process

myoblast fate commitment 3 | 3
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pituitary homeobox 1 PITX1 Tbio Transcription Factor -2.49247 314.9 173
Endothelial PAS domain-containing protein 1 EPAS1 Tchem Non-IDG -2.29071 180.5 477
Transcription factor 7-like 2 TCF7L2 Tbio Transcription Factor -2.63620 474.2 327