Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
corneal opacity 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased total body fat amoun... 1 | 207
edema 1 | 59
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

ovarian cancer 14 | 8,520
Cancer 13 | 2,499
Carcinoma 13 | 11,493
osteosarcoma 13 | 7,950
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
atypical teratoid / rhabdoid tumor 9 | 5,112
medulloblastoma, large-cell 9 | 6,241
lung adenocarcinoma 8 | 2,716
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
Waldenstrons macroglobulinemia 6 | 765
adult high grade glioma 6 | 3,801
cutaneous lupus erythematosus 6 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Astrocytoma, Pilocytic 5 | 3,081
Prostatic Neoplasms 5 | 495
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
primitive neuroectodermal tumor 5 | 3,035
Acute Promyelocytic Leukemia 4 | 40
Down syndrome 4 | 499
Leukemia, Promyelocytic, Acute 4 | 36
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Immune system cancer 3 | 140
Kidney cancer 3 | 2,613
Leukemia, Myelocytic, Acute 3 | 120
Leukemia, Myeloid, Acute 3 | 105
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Splenomegaly 3 | 190
Thrombocytopenia 3 | 197
Thrombocytosis 3 | 38
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Arthritis, Rheumatoid 2 | 174
Atopic dermatitis 2 | 952
Cardiomyopathies 2 | 110
Chest Pain 2 | 38
Delayed bone age 2 | 136
Ecchymosis 2 | 66
Epistaxis 2 | 43
Essential thrombocythemia 2 | 10
Fatigue 2 | 182
Fever 2 | 138
Globe disease 2 | 67
Headache 2 | 37
Hematologic cancer 2 | 12
Hepatomegaly 2 | 285
Hydronephrosis 2 | 89
Melanoma 2 | 711
Myeloproliferative disease 2 | 16
Neutropenia 2 | 72
Paresthesia 2 | 32
Pick disease 2 | 1,894
Polycythemia vera 2 | 27
Strabismus 2 | 270
Systemic lupus erythematosus 2 | 194
Venous Thrombosis 2 | 47
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
head and neck cancer 2 | 271
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 6 | 1,400
Enzyme 3 | 4,145
Epigenetic 2 | 242
Kinase 2 | 634

GO Process

myeloid cell differentiation 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Cyclin-dependent kinase inhibitor 1C CDKN1C Tbio Enzyme -2.81199 631.0 665
CCAAT/enhancer-binding protein alpha CEBPA Tbio Transcription Factor -2.94393 846.3 518
Zinc finger and BTB domain-containing protein 16 ZBTB16 Tbio Transcription Factor -2.31797 210.0 275
Gamma-interferon-inducible protein 16 IFI16 Tbio Non-IDG -1.96972 112.7 246
Interferon regulatory factor 8 IRF8 Tbio Transcription Factor -2.37977 273.3 336
Nuclear receptor coactivator 6 NCOA6 Tbio Non-IDG -1.83369 72.1 54
Core-binding factor subunit beta CBFB Tchem Transcription Factor -0.78193 5.82 291
Protein PML PML Tbio Non-IDG -2.63785 373.8 470