Development Level

Tbio 36 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 4 | 298
hyperactivity 3 | 148
preweaning lethality, complete... 3 | 979
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal skin morphology 2 | 50
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
increased vertical activity 2 | 24
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent testes 1 | 6
brachydactyly 1 | 19
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased granulocyte number 1 | 6
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
male infertility 1 | 123
short tibia 1 | 97
syndactyly 1 | 23
tremors 1 | 39

Disease

Carcinoma 29 | 11,493
ovarian cancer 29 | 8,520
atypical teratoid / rhabdoid tumor 27 | 5,112
glioblastoma 25 | 5,792
medulloblastoma, large-cell 25 | 6,241
ependymoma 24 | 4,679
osteosarcoma 22 | 7,950
Astrocytoma, Pilocytic 21 | 3,081
psoriasis 21 | 6,694
group 3 medulloblastoma 20 | 4,104
oligodendroglioma 20 | 2,850
Breast cancer 18 | 3,578
lung cancer 17 | 4,740
subependymal giant cell astrocytoma 17 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
primitive neuroectodermal tumor 15 | 3,035
adult high grade glioma 14 | 3,801
pancreatic cancer 14 | 2,398
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
Kidney cancer 12 | 2,613
cystic fibrosis 12 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Pick disease 11 | 1,894
invasive ductal carcinoma 11 | 2,951
Autosomal recessive predisposition 10 | 1,442
interstitial cystitis 10 | 2,312
non-small cell lung cancer 10 | 2,890
Muscle hypotonia 9 | 571
colon cancer 9 | 1,478
lung adenocarcinoma 9 | 2,716
Down syndrome 8 | 499
Neurodegenerative disease 8 | 414
Schizophrenia 8 | 1,160
Seizures 8 | 596
breast carcinoma 8 | 1,638
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 1,819
Epilepsy 7 | 792
Infantile onset 7 | 238
Neuropathy 7 | 261
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
Cancer 6 | 2,499
Cerebellar Ataxia 6 | 304
Peripheral Neuropathy 6 | 134
Bipolar Disorder 5 | 666
Charcot-Marie-Tooth disease 5 | 62
Duchenne muscular dystrophy 5 | 601
Dysarthria 5 | 192
Highly variable severity 5 | 157
Muscle Weakness 5 | 170
Polyneuropathy 5 | 64
Variable expressivity 5 | 157
cutaneous lupus erythematosus 5 | 1,057
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 807
medulloblastoma 5 | 720
nasopharyngeal carcinoma 5 | 1,058
Autistic Disorder 4 | 364
Cognitive delay 4 | 608
Decreased number of large and small myelinated fibers 4 | 20
Developmental regression 4 | 95
Distal limb muscle weakness due to peripheral neuropathy 4 | 62
Distal muscle weakness 4 | 62
Global developmental delay 4 | 608
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Intellectual disability 4 | 1,016
Loss of developmental milestones 4 | 95
Mental and motor retardation 4 | 608
Mental deterioration in childhood 4 | 95
Multiple Sclerosis 4 | 540
Muscle Spasticity 4 | 195
Neurodevelopmental regression 4 | 95
Neurogenic Muscular Atrophy 4 | 139
Neurogenic muscle atrophy, especially in the lower limbs 4 | 139
Optic Atrophy 4 | 242
Prostatic Neoplasms 4 | 495
Psychomotor regression 4 | 95
Psychomotor regression beginning in infancy 4 | 95
Psychomotor regression in infants 4 | 95
Psychomotor regression, progressive 4 | 95
Rheumatoid arthritis 4 | 1,191
Skeletal muscle atrophy 4 | 139
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
muscle degeneration 4 | 139
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676

Tissue

Digestive Tract 45 | 17,369
Nervous System 45 | 16,725
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Liver and Pancreas 44 | 16,750
Male tissues 44 | 17,142
Skin and soft tissues 44 | 17,230
Respiratory system 43 | 16,393
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 6 | 4,145
Ion Channel 3 | 344
Transcription Factor 3 | 1,400
GPCR 2 | 408
Kinase 1 | 634
Transporter 1 | 473

GO Process

myelination 45 | 45
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
NGFI-A-binding protein 1 NAB1 Tbio Non-IDG -1.09565 8.20 223
Myotubularin-related protein 13 SBF2 Tbio Non-IDG -1.38747 24.7 15
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
MARVEL domain-containing protein 1 MARVELD1 Tbio Non-IDG -1.58692 39.1 60
Oligodendrocyte transcription factor 2 OLIG2 Tbio Transcription Factor -2.64017 420.5 368
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301
Neurofascin NFASC Tbio Non-IDG -2.09540 119.2 154