Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 6 | 8,520
Carcinoma 4 | 11,493
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Charcot-Marie-Tooth disease 2 | 62
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Kidney cancer 2 | 2,613
Neurodegenerative disease 2 | 414
Neuropathy 2 | 261
Yunis-Varon syndrome 2 | 6
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
Abnormal auditory evoked potential 1 | 7
Abnormality of the scapula 1 | 3
Absent bone maturation in sternum 1 | 4
Absent sternal ossification 1 | 4
Amyotrophic lateral sclerosis type 11 1 | 3
Amyotrophic lateral sclerosis type 5 1 | 13
Ankle contracture 1 | 9
Anxiety 1 | 136
Anxiety disease 1 | 113
Aplastic clavicles 1 | 6
Arhinencephaly 1 | 5
Axonal loss 1 | 7
Biliary atresia 1 | 12
Body dysmorphic disorder 1 | 11
Cellulitis 1 | 20
Centronuclear myopathy 1 | 27
Charcot-Marie-Tooth disease type 4B1 1 | 1
Charcot-Marie-Tooth disease, Type 4B1 1 | 1
Colonic Polyps 1 | 3
Complex partial seizure with impairment of consciousness 1 | 9
Complex partial seizures 1 | 9
Congenital anomaly of neck 1 | 19
Congenital hypoplasia of clavicle 1 | 18
Decreased calcification of skull 1 | 10
Decreased motor NCV 1 | 22
Decreased nerve conduction velocity 1 | 35
Defect of skull ossification 1 | 10
Deformity of neck 1 | 19
Distal amyotrophy 1 | 51
Distal arthrogryposis syndrome 1 | 8
Dyspnea 1 | 76
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Fatigue 1 | 182
Fleck corneal dystrophy 1 | 9
Frequent falls 1 | 12
Hallucinations, Visual 1 | 6
Hemolytic anemia 1 | 77
Hydrops Fetalis 1 | 21
Hypoplastic facial bones 1 | 4
Hypoplastic finger 1 | 17
Hypoplastic lobules 1 | 11
Hypoplastic toes 1 | 29
Hypoplastic/aplastic distal phalanges 1 | 3
Idiopathic pulmonary arterial hypertension 1 | 40
Irregular myelin loops 1 | 1
Ischemic Attack, Transient 1 | 10
Kabuki syndrome 1 | 27
Leber congenital amaurosis 1 | 69
Malformation of the neck 1 | 19
Mood swings 1 | 77
Muscle Cramp 1 | 55
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Obstructive sleep apnea 1 | 26
Onion bulb formation 1 | 19
Pain 1 | 103
Paralysed 1 | 42
Peripheral hypomyelination 1 | 7
Precocious exfoliation of primary tooth 1 | 11
Pulmonary hypertension 1 | 85
Pyramidal tract syndrome 1 | 2
Short finger 1 | 17
Short to absent middle phalanges 1 | 5
Simpson-Golabi-Behmel syndrome 1 | 19
Single transverse palmar crease 1 | 29
Small facial bones 1 | 4
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sparse scalp hair 1 | 42
Tapering fingers (finding) 1 | 25
Tetralogy of Fallot 1 | 63
Thoracic Diseases 1 | 3
Thumb aplasia 1 | 16
Transient Ischemic Attack 1 | 10
Underdevelopment of facial bones 1 | 4
Upper motor neuron dysfunction 1 | 2
Xerostomia 1 | 42

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 2 | 4,145
Kinase 2 | 634
Non-IDG 2 | 12,091

GO Process

myelin assembly 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin-linked protein kinase ILK Tchem Kinase -2.75450 679.1 608
Myotubularin-related protein 2 MTMR2 Tbio Enzyme -1.64906 46.5 124
Glypican-1 GPC1 Tbio Non-IDG -2.38207 232.3 202
Polyphosphoinositide phosphatase FIG4 Tbio Enzyme -2.40083 231.8 177
1-phosphatidylinositol 3-phosphate 5-kinase PIKFYVE Tchem Kinase -2.20708 165.7 228
MAGUK p55 subfamily member 5 MPP5 Tbio Non-IDG -2.14012 137.2 221