Development Level

Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal placenta size 1 | 20
decreased mean corpuscular hem... 1 | 31
increased hematocrit 1 | 46
pallor 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
Bipolar Disorder 3 | 666
Cleft Palate 3 | 271
Myopathy 3 | 185
Psychotic Disorders 3 | 151
Rhabdomyosarcoma 3 | 39
Schizophrenia 3 | 1,160
atypical teratoid / rhabdoid tumor 3 | 5,112
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Autosomal recessive predisposition 2 | 1,442
Ectomesenchymoma 2 | 5
Nonorganic psychosis 2 | 84
Polycystic ovary syndrome 2 | 360
Skeletal muscle neoplasm 2 | 8
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
cystic fibrosis 2 | 1,696
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
22q11 Deletion Syndrome 1 | 10
22q11 partial monosomy syndrome 1 | 9
22q11.2 deletion syndrome 1 | 8
Abnormality of aortic arch 1 | 9
Abnormality of the endocrine system 1 | 9
Abnormality of the pharynx 1 | 19
Abnormality of the tonsils 1 | 10
Acne 1 | 52
Alveolar rhabdomyosarcoma 1 | 7
Ankylosis 1 | 28
Atrioventricular Septal Defect 1 | 22
Broad hallux 1 | 29
CONOTRUNCAL ANOMALY FACE SYNDROME 1 | 9
CONOTRUNCAL HEART MALFORMATIONS (disorder) 1 | 6
Cholelithiasis 1 | 33
Chromosome 22q11.2 microduplication syndrome 1 | 8
Cleft uvula 1 | 27
Congenital hypoplasia of kidney 1 | 32
Conotruncal Heart Malformations 1 | 10
Convex nasal bridge 1 | 57
Corneal Neovascularization 1 | 13
Decreased projection of midface 1 | 105
DiGeorge syndrome 1 | 47
Discordant ventriculoarterial connection 1 | 17
Double Outlet Right Ventricle 1 | 11
Dysphasia 1 | 23
Endocrine System Diseases 1 | 11
Exotropia 1 | 35
Familial hemophagocytic lymphohistiocytosis 1 1 | 11
Hand deformities 1 | 32
Hard palate cancer 1 | 10
Hernia, Femoral 1 | 7
Holt-Oram syndrome 1 | 12
Hypernasal voice 1 | 39
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Hypoplastic lobules 1 | 11
Hypotrophic midface 1 | 105
Impaired T cell function 1 | 14
Leri-Weill dyschondrosteosis 1 | 7
Midface retrusion 1 | 105
Mild Mental Retardation 1 | 70
Muscle Cramp 1 | 55
Myalgia 1 | 54
Myopathies, Structural, Congenital 1 | 15
Narrow face 1 | 54
Nasal voice 1 | 39
Occipital myelomeningocele 1 | 8
Open mouth 1 | 45
Overfolded helix 1 | 24
POLYDACTYLY, POSTAXIAL 1 | 13
Paranoia 1 | 20
Persistant truncus arteriosus 1 | 17
Platybasia 1 | 13
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Prominent nasal bridge 1 | 57
Retinitis pigmentosa 58 1 | 13
Rotting teeth 1 | 73
Sarcoma 1 | 62
Shprintzen syndrome 1 | 9
Sick sinus syndrome 1 | 15
Small midface 1 | 105
Small thymus 1 | 13
Spindle cell hemangioma 1 | 16
Tetany 1 | 18
Thin face 1 | 54
Thin hypoplastic alae nasi 1 | 51
Unilateral agenesis of kidney 1 | 20
Velocardiofacial syndrome 1 | 46
Waardenburg's syndrome 1 | 17
esophageal atresia/tracheoesophageal fistula 1 | 22
ulnar-mammary syndrome 1 | 8

Tissue

Digestive Tract 6 | 17,369
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Nervous System 5 | 16,725
Endocrine System 4 | 18,159
Urinary Tract 4 | 16,678
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Respiratory system 3 | 16,393

Target Family

Transcription Factor 5 | 1,400
Enzyme 1 | 4,145

GO Process

muscle tissue morphogenesis 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Paired box protein Pax-7 PAX7 Tbio Transcription Factor -2.70703 468.7 418
Short stature homeobox protein 2 SHOX2 Tbio Transcription Factor -1.65194 48.1 104
Myogenic factor 5 MYF5 Tbio Transcription Factor -2.51865 298.8 320
Myogenic factor 6 MYF6 Tbio Transcription Factor -2.08811 111.3 176